Masafumi Moriyama

2021 - 2025 インプラントガイドシステムを応用した上顎骨の高精度位置決め法の確立

2021 - 2024 Toll様受容体7シグナルに着目したIgG4関連疾患の新規治療法の開発

2021 - 2024 樹状細胞を新機軸とした骨吸収抑制薬関連顎骨壊死の病態解明と新規治療法・予防法開発

2021 - 2024 A Multicenter Study for the Introduction of Ultrasonography into the Diagnostic Criteria of IgG4-Related Dacryoadenitis and Sialadenitis

2020 - 2023 IgG4関連疾患の免疫学的特異性を基盤とした病因解明と疾患モデルマウスによる検証

2020 - 2023 唾液中の可溶性分子を用いたシェーグレン症候群の病因解析と新たな診断方法の開発

2019 - 2023 唾液中の可溶性マーカーに着目したIgG4関連疾患の新たな診断方法の開発

2019 - 2023 IgG4関連疾患とその世界初モデルマウスにおける臓器線維化メカニズム解明

2019 - 2023 シェーグレン症候群、IgG4関連涙腺唾液腺炎における腸内細菌叢と病態の関係の解明

2018 - 2023 IgG4関連疾患の病因解明と新規治療戦略 -特異なT・B細胞を標的として-

2018 - 2023 Establishment of non-invasive quantitative diagnostic method for salivary gland damage using ultrasound elastography

2022 - 2022 自然免疫を基盤とした慢性難治性唾液腺疾患の新規治療戦略

2018 - 2021 Novel therapeutic strategies for Sjogren's syndrome targeting Toll-like receptors.

2017 - 2020 Elucidation of mechanism on IgG4-related disease and establishment of disease model mouse

2017 - 2020 Japan-U.S. joint Research for establishment of international disease concept and new diagnostic criteria of IgG4-related disease

2016 - 2020 Relationship between Sjogren's syndrome and intestinal flora and intestinal immunity

2016 - 2020 Immunological study to elucidate the pathophysiology of HTLV-1-related Sjögren's syndrome

2018 - 2020 GPR56を標的とした加齢に伴う自己免疫疾患の診断及び治療薬の開発研究

2015 - 2019 Basic research for introducing sonographic diagnosis into international diagnostic criteria for Sjogren's syndrome

2015 - 2019 Saliva as a potential tool for diagnosis and severity classification of dry mouth including Sjogren's syndrome.

2014 - 2018 New strategy targeted at innate immunity for the pathologic clarification of new disease concept "IgG4-related disease"

2017 - 2018 国内初の汎用自動分析装置用IgG4測定試薬の多施設での評価

2018 - 2018 歯髄幹細胞の上清を用いたシェーグレン症候群の新たな治療戦略

2014 - 2017 Establishment of novel diagnostic method in oral candidiasis using LH-PCR and next-generation sequencing

2014 - 2017 The diagnostic utility of salivary examination in IgG4-related disease

2016 - 2017 腫瘍随伴性マクロファージを標的とした口腔扁平上皮癌の新規治療戦略

2016 - 2016 腫瘍随伴性マクロファージを標的とした口腔扁平上皮癌の新規治療戦略

2015 - 2016 IgG4関連疾患の病態形成における自然免疫担当細胞の関与

2015 - 2016 M2 マクロファージを標的としたIgG4 関連疾患の新規治療

2012 - 2015 Establishment of non-invasive image diagnosis of Sjogren's syndrome using near-infrared spectrometer, MRI and sonography

2013 - 2014 口腔扁平上皮癌の増殖・転移における腫瘍随伴性マクロファージの関与

2013 - 2014 IgG4関連疾患の新規標的分子の同定 -DNAマイクロアレイによる発現変動遺伝子の網羅的解析-

2013 - 2014 ミクリッツ病/IgG4関連疾患の病態解明および新規分子治療の開発

2011 - 2013 Saliva as a potential tool for diagnosis of dry mouth including Sjogren's syndrome

2010 - 2012 Molecular biological study on the pathogenesis of a novel clinical entity, Mikulicz's disease/ IgG4-related diseas

2008 - 2009 New treatment of Sjogren's syndrome and Mikulicz's disease/IgG4 related disease.