Higashijima Yoshiki

ヒガシジマヨシキ | Higashijima Yoshiki

Affiliation and department：
Job title： Associate professor

Research field (1)： Molecular biology

Research keywords (4)： enhancer , histone modification , transcription , epigenetics

Research theme for competitive and other funds (10)：

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Papers (23)：

Takeo Narita, Yoshiki Higashijima, Sinan Kilic, Tim Liebner, Jonas Walter, Chunaram Choudhary. Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes. Nature genetics. 2023. 55. 4. 679-692
Yuji Sasaki, Yoshiki Higashijima, Jun-Ichi Suehiro, Takehito Sugasawa, Eri Oguri-Nakamura, Shigetomo Fukuhara, Nao Nagai, Yosuke Hirakawa, Youichiro Wada, Masaomi Nangaku, et al. Lysine demethylase 2B regulates angiogenesis via Jumonji C dependent suppression of angiogenic transcription factors. Biochemical and biophysical research communications. 2022. 605. 16-23
Yasuharu Kanki, Masashi Muramatsu, Yuri Miyamura, Kenta Kikuchi, Yoshiki Higashijima, Ryo Nakaki, Jun-ichi Suehiro, Yuji Sasaki, Yoshiaki Kubota, Haruhiko Koseki, et al. Bivalent-histone-marked immediate-early gene regulation is vital for VEGF-responsive angiogenesis. Cell Reports. 2022. 38. 6. 110332-110332
Takashi Shimizu, Akashi Taguchi, Yoshiki Higashijima, Yasuharu Kanki, Ryo Nakaki, Yoshihiro Urade, Youichiro Wada. Inhibition of cardiac PERK signaling promotes peripartum cardiac dysfunction. Scientific reports. 2021. 11. 1. 18687-18687
Yoshiki Higashijima, Yasuharu Kanki. Potential roles of super enhancers in inflammatory gene transcription. The FEBS journal. 2021

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Books (1)：

Lectures and oral presentations (25)：

Elucidating the diuretic effect of corticosteroids in rats
(American Society of Nephrology 2023 2023)
遺伝子転写とヒストンアセチル化
(第13回トランスポーター研究会九州部会 2023)
新規転写エンハンサーマークとしてのヒストンH2BN末端アセチル化の同定
(第5回日本獣医薬理学・毒性学会春季研究会 2023)
A unique H2B acetylation signature marks active enhancers and predicts their target genes
(Precision Medicine Forum 2022, Epigenetics and Epigenomics in Health and Disease 2022)
Revising the function of transcriptional enhancer
(2022)

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Education (2)：

2012 - 2016 The University of Tokyo Graduate School of Medicine
2006 - 2012 University of Miyazaki Faculty of Agriculture Department of Veterinary Sciences

Professional career (1)：

Work history (7)：

2023/02 - 現在 University of Miyazaki Basic Veterinary Science, Institute for Promotion of Tenure Track Associate professor
2022/10 - 2023/02 Copenhagen University Novo Nordisk Foundation Center for Protein Research
2020/10 - 2022/09 Copenhagen University Novo Nordisk Foundation Center for Protein Research
2020/04 - 2020/09 Copenhagen University Novo Nordisk Foundation Center for Protein Research
2017/04 - 2020/03 Tokyo Medical and Dental University Medical Research Institute

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Awards (4)：

Association Membership(s) (2)：

日本生化学会 , 日本分子生物学会

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