2014 - 2017 Precise metal array methods using a template ranged from one atom to biomacromolecules
2016 - 2017 金属配位子型人工DNA鎖を鋳型とした金属ナノ粒子合成
2016 - 2017 生体微量金属イオンに応答する機能性人工核酸の創製
2009 - 2015 Creation of Supramolecular Complex Systems based on Dynamic Chemistry
2011 - 2015 自己複製超分子を指向した金属錯体型人工DNAのPCR様増幅サイクルの構築
2012 - 2013 金属錯体形成を駆動力とした構造可変型DNA ナノモチーフの構築
2011 - 2012 金属錯体型塩基対形成を駆動力とした自己複製型人工DNAの創製
2005 - 2009 Creation of Metal-mediated Nanolink Supramolecules
2005 - 2007 金属錯体型人工DNAによる金属イオンのヘテロ集積化と新規機能発現制御
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Papers (35)：
Yusuke Takezawa, Hanci Zhang, Keita Mori, Lingyun Hu, Mitsuhiko Shionoya. Ligase-mediated synthesis of CuII-responsive allosteric DNAzyme with bifacial 5-carboxyuracil nucleobases. Chemical Science. 2024. 15. 7. 2365-2370
Yusuke Takezawa, Keita Mori, Wei-En Huang, Kotaro Nishiyama, Tong Xing, Takahiro Nakama, Mitsuhiko Shionoya. Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases. Nature Communications. 2023. 14. 1
Keita Mori, Yusuke Takezawa, Mitsuhiko Shionoya. Metal-dependent base pairing of bifacial iminodiacetic acid-modified uracil bases for switching DNA hybridization partner. Chemical Science. 2023. 14. 5. 1082-1088
Lingyun Hu, Yusuke Takezawa, Mitsuhiko Shionoya. CuII-mediated DNA base pairing of a triazole-4-carboxylate nucleoside prepared by click chemistry. Chemical Communications. 2023
Silpa Chandran Rajasree, Yusuke Takezawa, Mitsuhiko Shionoya. CuII-mediated stabilisation of DNA duplexes bearing consecutive ethenoadenine lesions and its application to a metal-responsive DNAzyme. Chemical Communications. 2023
Yusuke Takezawa, Mitsuhiko Shionoya. Metal Ion-Induced Changes in the Stability of DNA Duplexes. Handbook of Chemical Biology of Nucleic Acids. 2023. 2645-2683
Yusuke Takezawa, Mitsuhiko Shionoya. Recent Advances in the Development of Metal-Responsive Functional DNAs Based on Metal-Mediated Artificial Base Pairing. 2023. 257-289
Y. Takezawa, M. Shionoya, J. Müller. Self-Assemblies Based on Metal-Mediated Artificial Nucleobase Pairing. Comprehensive Supramolecular Chemistry II. 2017. 4. 259-293
2003 - 2008 The University of Tokyo Graduate School of Science Department of Chemistry
1999 - 2003 The University of Tokyo School of Science Department of Chemistry
Work history (5)：
2012/04 - 現在 The University of Tokyo Department of Chemistry Assistant professor
2010/06 - 2012/03 The University of Tokyo Department of Chemistry Project assistant professor
2009/11 - 2010/05 RIKEN Systems and Structural Biology Center Research fellow
2009/04 - 2009/10 Nagoya University the Research Center for Materials Science Project assistant professor
2008/04 - 2009/03 Nagoya University the Research Center for Materials Science Postdoctoral researcher
Awards (4)：
2023/06 - Association of Research for Host-Guest and Supramolecular Chemistry SHGSC Japan Award of Excellence 2023 Rational Design of Metal-Responsive Functional DNA Supramolecules
2021/03 - Chemical Society of Japan CSJ Lecture Award for Young Chemists at The 101st CSJ Annual Meeting
2012 - Division of Biofunctional Chemistry, The Chemical Society of Japan The First International Symposium on Biofunctional Chemistry (ISBC2012) Poster Award
2012 - The Japan Science Society Sasakawa research award
Association Membership(s) (4)：
JAPAN SOCIETY OF COORDINATION CHEMISTRY
, THE CHEMICAL SOCIETY OF JAPAN
, Japan Society of Nucleic Acids Chemistry
, Association of Research for Host-Guest and Supramolecular Chemistry
