Maeda Tomoya

Research field (4)： Bacteriology , Evolutionary biology , Applied microbiology , Systems genomics

Research keywords (7)： Antibiotic resistance , Protoplast fusion , Metabolic engineering , RNase , Escherichia coli , Corynebacterium glutamicum , Laboratory evolution

Research theme for competitive and other funds (8)：

2024 - 2028 非病原性ウシ型結核菌BCG株を用いた進化実験による多剤耐性進化可能性の検証
2023 - 2026 Analysis of evolutionary dynamics of ecosystem using automated culture system
2022 - 2024 腸内マイクロバイオームの大規模継代培養による栄養共生関係の解明
2021 - 2024 適応的実験室進化による産業微生物のエネルギー欠乏への潜在的な適応能力の解明
2019 - 2022 Metabolic analysis of an Escherichia coli mutant defective in respiratory chain enzymes and its application to the production of 1,3-butanediol and gamma-aminobutyric acid.

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Papers (29)：

Tomoya Maeda, Chikara Furusawa. Laboratory Evolution of Antimicrobial Resistance in Bacteria to Develop Rational Treatment Strategies. Antibiotics. 2024. 13. 1. 94-94
Chikara FURUSAWA, Junichiro IWASAWA, Tomoya MAEDA. Inference of Fitness Landscape Based on Multi-Dimensional Phenotype Measurements of <i>Escherichia coli</i>. Seibutsu Butsuri. 2023. 63. 5. 263-265
Takashi Hirasawa, Tomoya Maeda. Adaptive Laboratory Evolution of Microorganisms: Methodology and Application for Bioproduction. Microorganisms. 2022. 11. 1
Junichiro Iwasawa, Tomoya Maeda, Atsushi Shibai, Hazuki Kotani, Masako Kawada, Chikara Furusawa. Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape. PLoS biology. 2022. 20. 12. e3001920
Angela Kranz, Tino Polen, Christian Kotulla, Annette Arndt, Graziella Bosco, Michael Bussmann, Ava Chattopadhyay, Annette Cramer, Cedric-Farhad Davoudi, Ursula Degner, et al. A manually curated compendium of expression profiles for the microbial cell factory Corynebacterium glutamicum. Scientific data. 2022. 9. 1. 594-594

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MISC (14)：

村上茉奈美, 川井隆太郎, 三吉健太, 芝井厚, 前田智也, 堀之内貴明, 古澤力, 古澤力, 戸谷吉博, 清水浩. Isoprenol production by co-culture with two Escherichia coli strains with consuming different carbon sources. 日本生物工学会大会講演要旨集. 2022. 74th
村上茉奈美, 川井隆太郎, 前田智也, 堀之内貴明, 古澤力, 古澤力, 戸谷吉博, 清水浩. Genomic mutation analysis of an evolved strain with enhanced mevalonate consumption. 日本生物工学会大会講演要旨集. 2021. 73rd
戸谷吉博, 川井隆太郎, 三吉健太, 村上茉奈美, 一色衣香, 堀之内貴明, 前田智也, 古澤力, 清水浩. 代謝シミュレーションと指向性進化に基づく有用物質生産微生物の開発. 化学工学会秋季大会研究発表講演要旨集(CD-ROM). 2021. 52nd
村上茉奈美, 川井隆太郎, 前田智也, 堀之内貴明, 古澤力, 戸谷吉博, 清水浩. Directed evolution for enhancing mevalonate uptake ability in Escherichia coli under a continuous culture. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
岩澤諄一郎, 前田智也, 堀之内貴明, 古澤力, 古澤力. 機械学習と大腸菌実験室進化データを用いた進化拘束の解析. 日本ゲノム微生物学会年会要旨集. 2020. 14th

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Education (3)：

2008 - 2012 Tokyo Institute of Technology, Graduate School Graduate School of Bioscience and Biotechnology Department of Bioengineering
2009 - 2010 University of Cologne Institute for Biochemistry
2004 - 2008 Tokyo Institute of Technology School of Bioscience and Biotechnology Department of Bioengineering

Professional career (1)：

Ph.D. (Tokyo Institute of Technology)

Work history (7)：

2021/02 - 現在 Hokkaido University Graduate School of Agriculture Research Faculty of Agriculture Assistant professor
2021 - 現在 RIKEN Center for Biosystems Dynamics Research Visiting Researcher
2018/04 - 2021/01 RIKEN Center for Biosystems Dynamics Research Special Postdoctoral Researcher
2016/01 - 2017/03 RIKEN Quantitative Biology Center Postdoctoral researcher
2013/09 - 2015/12 Research Institute of Innovative Technology for the Earth Molecular Microbiology and Biotechnology Group Researcher

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Awards (2)：

2021/01 - 理化学研究所 Presentation award Biology Prize
2012/03 - 生物工学研究会鎌田泉博士論文賞

Association Membership(s) (3)：

Society of Genome Microbiology, Japan , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , The Society for Biotechnology, Japan

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