Goto Akiteru

Affiliation and department：

Research field (1)： Human pathology

Research keywords (4)：腫瘍関連マクロファージ , マイクロRNA , 診断病理学 , 肺癌

Research theme for competitive and other funds (28)：

2023 - 2027 Gene-environment interactions inducing spatial expansion of mutant clones in human normal tissues
2024 - 2027 肺腺癌の発生進展に対する全ゲノム重複(WGD: Whole Genome Doubling)の関与
2022 - 2025 正常卵管上皮の変異細胞集塊に着目した婦人科癌のゲノム病理学的研究
2023 - 2024 手術検体迅速検査による腫瘍特性把握法の開発とその応用
2020 - 2023 Analysis of aberrant Akt/mTOR signature for the precision medicine in lung carcinoma

2019 - 2022 Pathological and genomic analyses of uterine sarcoma by next generation sequencing

2019 - 2022 Analyses of Tumor-Associated Macrophage in Lung Cancer with Next Generation Sequence and Tissue Clearing

2017 - 2020 Dysregulation of AKT network and its application for precision medicine in lung cancer

2017 - 2019 Study of novel CAF led-type cancer invasion triggered by cancer death vesicles

2014 - 2018 Involvement of Akt/mTOR in lung cancer and design of novel therapy targeting them

2013 - 2016 Analysis of cell-context dependent features of adhesion molecules for cancer diagnosis

2013 - 2016 Chemoresistance of non-small cell lung cancer-Its prediction by combination of tumor characteristics and personal predisposition

2012 - 2014 秋田県における成人T細胞性白血病の分子疫学・分子病理学的調査.

2012 - 2013 被災地等遠隔医療にも応用可能な癌の位相幾何的アルゴリズム診断技術の開発

2011 - 2013 細胞接着・運動性経路を標的としたATL細胞の浸潤、増殖抑制医薬品開発のための基礎研究

2010 - 2013 Invasion-associated microRNA of small lung adenocarcinoma-A detailed study using laser microdissection

2010 - 2012 Physiological and pathological analyses of cell adhesion molecules towards the development of diagnostic markers of human cancer

2007 - 2010 SV40 as a human oncogenic virus. Molecular epidemiology in Japan and Asia.

2006 - 2008 特発性肺線維症における発癌-炎症と喫煙の複合作用に着目した高癌化状態の解明

2003 - 2007 肺癌,食道癌におけるヒトパピローマウイルスの役割.日本,アジアにおける分子疫学

2006 - 2007 Clinicopathological analysis of lung adenocarcinomas by EGFR gene mutation and gene expression analysis

2006 - 2007 特発性肺線維症における発癌-炎症と喫煙の複合作用に着目した高癌化状態の解明

2003 - 2006 Human papilloma virus in lung and esophageal carcinoma. Molecular pathology of Japan and Asia

2001 - 2005 肺腺癌の診断,悪性度診断の客観化を目指した遺伝子診断システムの確立

2004 - 2005 非小細胞肺癌におけるP27発現低下の研究

2003 - 2004 肺腺癌におけるCdkインヒビターp27分解の研究

2001 - 2004 肺腺癌の診断,悪性度診断の客観化を目指した遺伝子診断システムの確立

2002 - 2003 肺腺癌におけるskp2異常の研究.

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Papers (133)：

Hikaru Tsukita, Kei Koyama, Takahiro Ishinari, Ayana Takahashi, Ken Miyabe, Michinobu Umakoshi, Makoto Yoshida, Yukitsugu Kudo-Asabe, Akiko Nishida, Naohiko Otsuka, et al. A case of pancreatic PEComa with prominent inflammatory cell infiltration: the inflammatory subtype is a distinct histologic group of PEComa. Diagnostic pathology. 2024. 19. 1. 59-59
Tatjana Geukens, Marion Maetens, Jody E Hooper, Steffi Oesterreich, Adrian V Lee, Lori Miller, Jenny M Atkinson, Margaret Rosenzweig, Shannon Puhalla, Heather Thorne, et al. Research autopsy programmes in oncology: shared experience from 14 centres across the world. The Journal of pathology. 2024
Kaori Yoshimura, Yukinobu Ito, Mina Suzuki, Masafumi Horie, Takumi Nishiuchi, Yukako Shintani-Domoto, Kazuyoshi Shigehara, Hiroko Oshima, Masanobu Oshima, Akiteru Goto, et al. Identification of uromodulin deposition in the stroma of perinephric fibromyxoid nephrogenic adenoma by mass spectrometry. Pathology international. 2024
Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, Yataro Daigo, Syuzo Kaneko, Takahisa Kawaguchi, Hideo Kunitoh, Shingo Matsumoto, Hidehito Horinouchi, Akiteru Goto, et al. Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses. Cancer communications (London, England). 2023
Misato Horie, Kurara Takagane, Go Itoh, Sei Kuriyama, Kazuyoshi Yanagihara, Masakazu Yashiro, Michinobu Umakoshi, Akiteru Goto, Junichi Arita, Masamitsu Tanaka. Exosomes secreted by ST3GAL5high cancer cells promote peritoneal dissemination by establishing a pre-metastatic microenvironment. Molecular oncology. 2023

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MISC (293)：

後藤明輝, 小山慧. 【病理形態学キーワード2024】(第2章)肺非腫瘍蜂巣肺. 病理と臨床. 2024. 42. 臨増. 28-29
後藤明輝, 小山慧. 【病理形態学キーワード2024】(第2章)肺非腫瘍硝子膜. 病理と臨床. 2024. 42. 臨増. 32-33
後藤明輝, 小山慧. 【病理形態学キーワード2024】(第2章)肺非腫瘍胸膜肺実質線維弾性化. 病理と臨床. 2024. 42. 臨増. 34-35
後藤明輝, 小山慧. 【病理形態学キーワード2024】(第2章)肺非腫瘍蔓状病変. 病理と臨床. 2024. 42. 臨増. 40-41
後藤明輝, 小山慧. 【病理形態学キーワード2024】(第2章)肺非腫瘍含鉄・石綿小体. 病理と臨床. 2024. 42. 臨増. 46-47

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Books (5)：

腫瘍病理鑑別診断アトラス肺癌第2版前浸潤性病変 (1)扁平上皮異形成、上皮内(扁平上皮)癌
文光堂 2022 ISBN:9784830622618
腫瘍病理鑑別診断アトラス肺癌第2版扁平上皮癌 (2)リンパ上皮腫様癌
文光堂 2022 ISBN:9784830622618
腫瘍病理鑑別診断アトラス肺癌第2版扁平上皮癌(1)扁平上皮癌(角化型、非角化型、類基底細胞型)
文光堂 2022 ISBN:9784830622618
Suzuki T., Poignard C., Chaplain M., Quaranta V. (eds) Methods of Mathematical Oncology. MMDS 2020. Springer Proceedings in Mathematics & Statistics, vol 370.
Springer, Singapore. 2021
はじめの一歩の病理学
羊土社 2017 ISBN:9784758120845

Education (2)：

1995 - 1999 東京大学大学院医学系研究科
1989 - 1995 The University of Tokyo Faculty of Medicine School of Medicine

Professional career (2)：

博士(医学) (東京大学)
学士(医学) (東京大学)

Work history (5)：

2011/10 - 現在 Akita University Graduate School of Medicine
2010/10 - 2011/09 The University of Tokyo The Institute of Medical Science, Division of Molecular Pathology
2001/04 - 2010/09 The University of Tokyo Graduate School of Medicine
2007/04 - 2009/03 米国立がん研究所 (National Cancer Institute) Laboratry of Human Carcinogenesis 博士研究員
1999/04 - 2001/03 Kyorin University Faculty of Medicine

Committee career (16)：

2024/04 - 現在日本病理学会・国立がん研究センター病理診断コンサルテーションシステム病理コンサルタント
2023/01 - 現在 Pathology International Editorial Board
2022/11 - 現在 Japanese Journal of Clinical Oncology Reviewer Board
2021/01 - 現在 BMC Cancer Editorial Board
2019/10 - 現在労働者健康安全機構労働安全衛生研究評価部会専門委員

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Association Membership(s) (3)：

THE JAPANESE SOCIETY FOR IMMUNOLOGY , THE JAPAN LUNG CANCER SOCIETY , THE JAPANESE SOCIETY OF PATHOLOGY

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