2017 - 2020 Comprehensive identification and functional elucidation of regulators of histone modifications that regulate germ cell fate
2016 - 2020 Development of efficient and versatile method for inducing neuronal differentiation with temperature-controlled repeated thermal stimulation (TRTS)
Kentaro Mochizuki, Jafar Sharif, Kenjiro Shirane, Kousuke Uranishi, Aaron B Bogutz, Sanne M Janssen, Ayumu Suzuki, Akihiko Okuda, Haruhiko Koseki, Matthew C Lorincz. Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing. Nature communications. 2021. 12. 1. 7020-7020
Kaichi Yoshizaki, Ryuichi Kimura, Hisato Kobayashi, Shinya Oki, Takako Kikkawa, Lingling Mai, Kohei Koike, Kentaro Mochizuki, Hitoshi Inada, Yasuhisa Matsui, et al. Paternal age affects offspring via an epigenetic mechanism involving REST/NRSF. EMBO reports. 2021. 22. 2. e51524
Misako Tatehana, Ryuichi Kimura, Kentaro Mochizuki, Hitoshi Inada, Noriko Osumi. Comprehensive histochemical profiles of histone modification in male germline cells during meiosis and spermiogenesis: Comparison of young and aged testes in mice. PloS one. 2020. 15. 4. e0230930
Characterization of the molecular basis of DNA hypomethylation in Rahman syndrome: Do gain-of-function histone H1 mutations globally disrupt deposition of H3K36me2?
(8th Canadian Conference on Epigenetics 2022)
Dissecting the roles of H3K27me3 and H2AK119ub1 in transcriptional silencing following NSD1 depletion.
(8th Canadian Conference on Epigenetics 2022)
Role of UHRF1 binding to H3K9me3 in DNAme maintenance at heterochromatic regions in naïve embryonic stem cells.
(8th Canadian Conference on Epigenetics 2022)
ChIP-seq Spike-In Normalization: The Good, the Bad, and the Ugly.
(8th Canadian Conference on Epigenetics 2022)
Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing.
(8th Canadian Conference on Epigenetics 2022)