Research theme for competitive and other funds (10):
2023 - 2027 Mechanisms of impaired olfactory epithelial regeneration in eosinophilic chronic rhinosinusitis: focusing on the involvement of type 2 cytokines.
2023 - 2026 アレルゲン特異的免疫療法の効果発現における細胞外小胞の役割解明
2023 - 2025 アレルゲン特異的免疫療法による2型自然リンパ球の制御機構の解明
2023 - 2024 デザイナー細胞外小胞を用いた食物アレルギーの予防・治療法の創出
2021 - 2023 アレルギー疾患の根治を指向したTr1細胞誘導性エクソソームの創出
2020 - 2023 Analyses of induction mechanisms underlying steroid-resistant asthma by focusing on "Epimmunome"
2020 - 2022 Asthma-COPD overlapに対するtype 1 regulatory T 細胞由来エキソソームの消炎作用の解明
2019 - 2021 Elucidation of mechanisms for induction of regulatory T cells by IgG1 that increase in allergen immunotherapy
2020 - 2021 脂溶性ビタミン製剤はアレルゲン免疫療法のアジュバントになり得るか
2017 - 2020 Elucidation of pathogenesis of intractable asthma by analyzing immunological mechanisms of IL-33 production
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Papers (23):
Hayato Shimora, Masaya Matsuda, Yukiko Nakayama, Hiroto Maeyama, Ryunosuke Tanioka, Yoshiyuki Tanaka, Kazuyuki Kitatani, Takeshi Nabe. Involvement of Janus kinase-dependent Bcl-xL overexpression in steroid resistance of group 2 innate lymphoid cells in asthma. Immunology. 2024. 1-16
Masaya Matsuda, Hayato Shimora, Yukino Nagatani, Keitaro Nishikawa, Itomi Takamori, Tenta Haguchi, Kazuyuki Kitatani, Osamu Kaminuma, Takeshi Nabe. Involvement of CCR5 on interstitial macrophages in the development of lung fibrosis in severe asthma. International Immunopharmacology. 2024. 135. 30. 112331
Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro, Nishida, Yasuhiro Miki, Todd E. Fox, Mark Kester, Wataru Sakamoto, et al. Pronecroptotic therapy using ceramide nanoliposomes is effective for triple-negative breast cancer cells. Cells. 2024. 13. 405
Hayato ShimoraMasaya, MatsudaNaoki TakemotoMiku NomuraJunpei, HamaguchiRyogo TerakawaKazuyuki KitataniTakeshi Nabe. Steroid-insensitive gene expression of extracellular matrix components and pro-fibrotic factors in the lung associated with airway hyperresponsiveness in murine asthma. Biological and Pharmaceutical Bulltein. 2024. 47. 1. 227-231
Takeshi Nabe, Masaya Matsuda. Anti-inflammatory Strategies by Focusing on the Particularity of Ocular Immunity. YAKUGAKU ZASSHI. 2021. 141. 12. 1327-1332
JAPANESE SOCIETY OF ALLERGOLOGY
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE PHARMACOLOGICAL SOCIETY
, アレルギー・好酸球研究会
, 日本眼薬理学会