2014 - 2018 Study on the molecular mechanism of psychiatric disorders that targets PACAP signaling pathways and aimed at the development of therapeutic drug
2013 - 2016 シナプス病態に関わるPACAPによるスパイン動態制御機構の解析
2011 - 2013 PACAP plays significant roles in dendritic spine morphology using optogenetics.
2011 - 2012 Functional analyses of novel mitochondrial fusion inhibitor HPGBin the regulation of heart and metabolism
2009 - 2011 Molecular basis study on PACAP gene as a risk factor for schizophrenia
2006 - 2007 ゲノム工学を用いて作製した自閉症マウスの解析による精神機能の分子的基盤研究
2006 - 2007 概日リズムのDECODEシステムの解明
2006 - 2007 Molecular mechanism of circadian oscillation by real-time rhythm monitoring
2006 - 2007 リチウムシグナルと概日リズムからみたそううつ病病態への分子的アプローチ
2005 - 2005 ゲノム工学を用いて作製した自閉症マウスの解析による精神機能の分子的基盤研究
2002 - 2003 哺乳類の概日リズムの体内時計の分子機構:CK1εの役割
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Papers (70)：
Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
Satoshi Asano, Ami Ono, Kaede Baba, Teru Uehara, Kotaro Sakamoto, Atsuko Hayata-Takano, Takanobu Nakazawa, Souichi Yanamoto, Kotaro Tanimoto, Hitoshi Hashimoto, et al. Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells. Journal of pharmacological sciences. 2024. 154. 3. 139-147
Misaki Iwahashi, Takeshi Yoshimura, Wakana Harigai, Kazuhiro Takuma, Hitoshi Hashimoto, Taiichi Katayama, Atsuko Hayata-Takano. Pituitary Adenylate Cyclase-Activating Polypeptide deficient mice show length abnormalities of the axon initial segment. Journal of Pharmacological Sciences. 2023
Satoshi Asano, Ami Ono, Kotaro Sakamoto, Atsuko Hayata-Takano, Takanobu Nakazawa, Kotaro Tanimoto, Hitoshi Hashimoto, Yukio Ago. Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway. Peptides. 2023. 161. 170940-170940
Yusuke Shintani, Yui Yamano, Manato Kuta, Rei Takeshita, Kazuhiro Takuma, Takuya Okada, Naoki Toyooka, Ichiro Takasaki, Atsuro Miyata, Takashi Kurihara, et al. Small-molecule non-peptide antagonists of the PACAP receptor attenuate acute restraint stress-induced anxiety-like behaviors in mice. Biochem Biophys Res Commun . 2022. 631. 146-151
The effects of PACAP-PAC1 signal blockade in the medial prefrontal cortex on repeated social defeat stress mice
(第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会 2023)
Abnormality of axon initial segment in mice with attention-deficit hyperactivity disorder (ADHD)-like behavior and that recovery by the drug for ADHD.
(第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会 2023)
2009/01 - 2011/03 Osaka University Graduate School of Medicine
2004/04 - 2008/12 大阪バイオサイエンス研究所 特別研究員
2003/04 - 2004/03 日本学術振興会特別研究員PD
2002/04 - 2003/03 日本学術振興会特別研究員DC2
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Committee career (2)：
2018 - 現在 日本精神神経学会 評議員
2018/01 - 現在 日本薬理学会 学術評議員
Awards (5)：
2022/11 - BPCNPNPPP4学会合同年会 優秀演題発表賞
2018/06 - CINP CINP2018 Award for the Best Poster
2014/06 - JSNP Excellent Presentation Award for CINP2014
2014/05 - 大阪大学 平成26年度 大阪大学総長奨励賞
2012/06 - 日本神経精神薬理学会 JSNP Excellent Presentation Award for CINP2012
Association Membership(s) (5)：
The International College of Neuropsychopharmacology
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE JAPANESE SOCIETY FOR NEUROCHEMISTRY
, THE JAPANESE PHARMACOLOGICAL SOCIETY
, THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY
