Rchr
J-GLOBAL ID:201801003924032895   Update date: Apr. 01, 2024

NISHIMURA TAKI

ニシムラ タキ | NISHIMURA TAKI
Research field  (2): Morphology, anatomy ,  Pharmaceuticals - health and biochemistry
Research keywords  (3): オルガネラコンタクトサイト ,  autophagy ,  lipid transfer protein
Research theme for competitive and other funds  (10):
  • 2024 - 2027 革新的なオンデマンド脂質プローブ作成技術の確立
  • 2021 - 2024 ポストリソソームシグナルを駆動する脂質因子の解析
  • 2021 - 2024 動的なオルガネラコンタクトネットワーク制御機構の解明
  • 2022 - 2023 脂質プローブ作成に向けたペプチドスクリーニング系の構築
  • 2014 - 2020 オートファゴソーム形成とグリセロリン脂質生合成系の密接な関係
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Papers (27):
  • Takahiro Shimizu, Norito Tamura, Taki Nishimura, Chieko Saito, Hayashi Yamamoto, Noboru Mizushima. Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration. Human Molecular Genetics. 2023
  • Taki Nishimura, Gianmarco Lazzeri, Noboru Mizushima, Roberto Covino, Sharon A Tooze. Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3. Science advances. 2023. 9. 25. eadh1281
  • Wenxin Zhang, Taki Nishimura, Deepanshi Gahlot, Chieko Saito, Colin Davis, Harold B J Jefferies, Anne Schreiber, Lipi Thukral, Sharon A Tooze. Autophagosome membrane expansion is mediated by the N-terminus and cis-membrane association of human ATG8s. eLife. 2023. 12
  • Sharon A Tooze, Wenxin Zhang, Gianmarco Lazzeri, Deepanshi Gahlot, Lipi Thukral, Roberto Covino, Taki Nishimura. Membrane association of the ATG8 conjugation machinery emerges as a key regulatory feature for autophagosome biogenesis. FEBS letters. 2023
  • Taki Nishimura. A Real-Time Phosphatidylinositol 4-Phosphate 5-Kinase Assay Using Fluorescence Spectroscopy. Methods in Molecular Biology. 2021. 121-132
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MISC (22):
  • 西村多喜. リソソーム膜脂質を可視化する脂質プローブの作製. 第23回日本蛋白質科学会年会. 2023
  • 西村多喜. オンデマンド脂質プローブ作製技術. 第96回日本生化学会大会. 2023
  • 西村多喜. 両親媒性αヘリックスが操るオートファジー関連分子ATG3の機能. 第60回日本生物物理学会年会. 2022
  • 西村多喜. 脂質交換反応によるホスファチジルイノシトールリン脂質代謝制御機構. 第62回脂質生化学会. 2020
  • Nishimura, T, Gecht, M, Covino, R, Hummer, G, Arai, H, Kono, N, Stefan C.J. An Essential Role for the Conserved ORP Lipid Transfer Proteins in PM Organization. 60th International Conference on the Bioscience of Lipids. 2019
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Patents (1):
  • 目的タンパク質の単離方法,及び目的タンパク質の単離キット
Education (2):
  • 2002 - 2004 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 2000 - 2002 The University of Tokyo College of Arts and Sciences
Work history (10):
  • 2024/04 - 現在 Osaka University Institute for Protein Research Professor
  • 2021/04 - 2024/03 東京大学大学院医学系研究科 (水島昇教授) さきがけ専任研究員
  • 2019/04 - 2021/03 The Francis Crick Institute Molecular Cell Biology of Autophagy Laboratory Post-Doc
  • 2016/01 - 2019/03 University College London, MRC-LMCB Chris Stefan Lab Research fellow
  • 2013/01 - 2015/12 The University of Tokyo Graduate School of Medicine
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Association Membership(s) (3):
THE JAPANESE BIOCHEMICAL SOCIETY ,  日本生物物理学会 ,  日本細胞生物学会
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