Research field (1)：
General surgery, pediatric surgery
Research theme for competitive and other funds (13)：
2020 - 2025 エピジェネティクス制御による胆道閉鎖症術後黄疸消失機構の解明
2017 - 2021 Research on the etiology and disease progression of biliary atresia focusing on various obstructive types and gene expression
2014 - 2018 Role of omega-3 fatty acids in intestinal immunomodulating
2013 - 2017 A study of microRNA expression in biliary atresia
2011 - 2015 New immunosuppressive therapy targeted to the intestinal macrophage for intestinal transplantation
2009 - 2014 Development of the treatment strategy for childhood refractory sarcoma trying to use iPS technology for possible reprogramming of cancer stem cell.
2001 - 2002 Roles of cell-cell adhesion molecules and apoptpsis effectors in the pathogenesis and disease processes of biliary atresia. Gene profiling assay using cDNA microarray
1999 - 2000 Attempt of producing an experimental animal model of biliary atresia using bcl-2 knock-out mice : the analysis of bcl-2 as the apoptosis inhibitor in biliary atresia
1998 - 1999 腸管筋層における転写因子MITF isoformによるC-KIT発現調節
1997 - 1998 Apoptosis and Cell Proliferation in Biliary Atresia
1995 - 1996 Biliary atresia and Cytokine
1994 - 1996 The absorption study with BMIPP in a swine model of partial small intestinal transplantation
1991 - 1992 Molecular Biological Studies on Pathogenesis of Biliary Atresia Using PCR method
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Papers (526)：
Akihiro Asai, Jia-Feng Wu, Kasper S Wang, Atsuyuki Yamataka, Masaki Nio, Da-Jyun Su, Celia Short, Koichi Tsuboi, Takanori Ochi, Hideyuki Sasaki, et al. The Outcome of Patients With Cystic Biliary Atresia With Intact Proximal Hepatic Ducts Following Hepatic-Cyst-Jejunostomy. Journal of pediatric gastroenterology and nutrition. 2022. 75. 2. 131-137
Yudai Nakajima, Yuto Yamazaki, Xin Gao, Masatoshi Hashimoto, Masaki Nio, Motoshi Wada, Fumiyoshi Fujishima, Hironobu Sasano. Association between mitochondrial and nuclear DNA damages and cellular senescence in the patients with biliary atresia undergoing Kasai portoenterostomy and liver transplantation. Medical molecular morphology. 2022. 55. 2. 131-145
