Rchr
J-GLOBAL ID:201801004148085033   Update date: Nov. 06, 2024

Heissig Beate

Heissig Beate
Affiliation and department:
Job title: Specially Appointed Associate Professor
Research field  (1): Hematology and oncology
Research keywords  (5): 再生医学 ,  免疫学 ,  腫瘍学 ,  血液学 ,  幹細胞生物学
Research theme for competitive and other funds  (14):
  • 2022 - 2024 Elucidation of pathological control mechanisms involving the tPA / tPA receptor pathway in multiple myeloma
  • 2021 - 2024 tPA/tPA受容体シグナルによる多発性骨髄腫の病態制御機構の解明
  • 2019 - 2022 Role of the angiocrine factor Egfl7 in multiple myeloma progression and drug resistance
  • 2016 - 2019 Fibrinolytic factors control MSC expansion thereby enhancing hematopoiesis
  • 2013 - 2016 Studies in the action mechanism of fibrinolytic system on the inflammatory bowel disease and its clinical applications
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Papers (96):
  • Salama Y, Munakata S, Osada T, Takahashi S, Hattori K, Heissig B. Heparin-binding EGF-Like Growth Factor via miR-126 controls tumor formation/growth and the proteolytic niche in murine models of colorectal and colitis-associated cancers. Cell Death Dis. 2024. 15. 753
  • Maksym Skrypnyk, Tetiana Yatsenko, Oleksandra Riabets, Yousef Salama, Margarita Skikevych, Taro Osada, Morikuni Tobita, Satoshi Takahashi, Koichi Hattori, Beate Heissig. Interleukin-10 induces TNF-driven apoptosis and ROS production in salivary gland cancer cells. Heliyon. 2024. 10. 11. e31777-e31777
  • Tetiana Yatsenko, Ricardo Rios, Tatiane Nogueira, Yousef Salama, Satoshi Takahashi, Eisuke Adachi, Yoko Tabe, Nobutaka Hattori, Taro Osada, Toshio Naito, et al. The influence of 4G/5G polymorphism in the plasminogen-activator-inhibitor-1 promoter on COVID-19 severity and endothelial dysfunction. Frontiers in immunology. 2024. 15. 1445294-1445294
  • Tetiana Yatsenko, Ricardo Rios, Tatiane Nogueira, Yousef Salama, Satoshi Takahashi, Yoko Tabe, Toshio Naito, Kazuhisa Takahashi, Koichi Hattori, Beate Heissig. Corrigendum: Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19. Frontiers in immunology. 2024. 15. 1390698-1390698
  • Mizoue, Y, Ikeda, T, Ikegami, T, Riabets, O, Oishi, Y, Tobita,, M, Akutsu, H, Hattori, K, Heissig, B, Koide, H. The stem cell transcription factor ZFP296 transforms NIH3T3 cells and promotes anchorage-independent growth of cancer cells. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 2023. 67. 4. 147-153
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MISC (86):
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Patents (4):
  • COVID-19の重症化を予測する血中バイオマーカー
  • 炎症性疾患治療剤
  • 組織プラスミノーゲン活性化因子を使用した末梢血幹細胞動員及び組織再生促進
  • 血管新生方法及び血管新生剤
Education (2):
  • 1993 - マールブルグ・フィリップス大学 医学部 大学院医学研究科
  • 1990 - マールブルグ・フィリップス大学 医学部
Professional career (1):
  • 医学博士 (マールブルグ大学)
Work history (14):
  • 2021/10 - 現在 Juntendo University, Graduate School of Medicine Department of Research Support Utilizing Bioresource Bank Specially Appointed Associate Professor
  • 2019/04 - 2021/09 Juntendo University Graduate School of Medicine
  • 2012 - 2019/03 The University of Tokyo The Institute of Medical Science
  • 2010 - The University of Tokyo The Institute of Medical Science
  • 2007 - The University of Tokyo The Institute of Medical Science
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Awards (4):
  • 2020/11 - JSPS Alumni Club Award (JACA) JSPS Alumni Club Award (JACA) JSPS Alumni Club Award (JACA)
  • 2004/11 - International Medical Society of Japan (IMSJ) Ishibashi Memorial Award IMSJ Ishibashi Memorial Award IMSJ
  • 2003 - 米国白血病・リンパ腫協会 研究助成スペシャルフェロー
  • 2003 - アレキサンダー・フォン・フンボルト財団 長期フェローシップ
Association Membership(s) (2):
American Association for Cancer Research ,  American Society of Hematology
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