Rchr
J-GLOBAL ID：201801004148085033
Update date: Apr. 18, 2024
Heissig Beate
Heissig Beate
Affiliation and department：
Job title：
Specially Appointed Associate Professor
Research field (1)：
Hematology and oncology
Research keywords (5)：
再生医学
, 免疫学
, 腫瘍学
, 血液学
, 幹細胞生物学
Research theme for competitive and other funds (14)：
- 2022 - 2024 Elucidation of pathological control mechanisms involving the tPA / tPA receptor pathway in multiple myeloma
- 2021 - 2024 tPA/tPA受容体シグナルによる多発性骨髄腫の病態制御機構の解明
- 2019 - 2022 Role of the angiocrine factor Egfl7 in multiple myeloma progression and drug resistance
- 2016 - 2019 Fibrinolytic factors control MSC expansion thereby enhancing hematopoiesis
- 2013 - 2016 Studies in the action mechanism of fibrinolytic system on the inflammatory bowel disease and its clinical applications
- 2012 - 2015 Multifunctional role of Membrane-type 1 matrix metalloproteinase in multiple myeloma
- 2010 - 2015 Functional analysis of the fibrinolytic system in bone marrow-derived cell mediated tumor angiogenesis and growth
- 2009 - 2011 The role of plasmin in the regulation of the multiple myeloma microenvironment
- 2008 - 2009 血管内皮細胞由来因子EGFL7のがん血管新生における機能解析
- 2006 - 2007 脂肪細胞ニッチにおけるADAMsプロテイナーゼの機能的解析
- 2006 - 2007 新しい血管内皮細胞由来因子EGFL7のがん血管新生における機能解析
- 2005 - 2006 Role of fibrinolytic factors in the regulation of hematopoiesis
- 2003 - 2004 Platelets support tumor growth by promoting angiogenesis (Searching for the angiogenic switch)
- 進行中の研究課題・終了した研究課題
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Papers (93)：
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Tetiana Yatsenko, Ricardo Rios, Tatiane Nogueira, Yousef Salama, Satoshi Takahashi, Yoko Tabe, Toshio Naito, Kazuhisa Takahashi, Koichi Hattori, Beate Heissig. Corrigendum: Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19. Frontiers in immunology. 2024. 15. 1390698-1390698
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Mizoue, Y, Ikeda, T, Ikegami, T, Riabets, O, Oishi, Y, Tobita,, M, Akutsu, H, Hattori, K, Heissig, B, Koide, H. The stem cell transcription factor ZFP296 transforms NIH3T3 cells and promotes anchorage-independent growth of cancer cells. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 2023. 67. 4. 147-153
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Tetiana Yatsenko, Maksym Skrypnyk, Olga Troyanovska, Morikuni Tobita, Taro Osada, Satoshi Takahashi, Koichi Hattori, Beate Heissig. The Role of the Plasminogen/Plasmin System in Inflammation of the Oral Cavity. Cells. 2023. 12. 3. 445-445
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Tetiana Yatsenko, Ricardo Rios, Tatiane Nogueira, Satoshi Takahashi, Yoko Tabe, Toshio Naito, Kazuhisa Takahashi, Koichi Hattori, Beate Heissig. Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19. Frontiers in immunology. 2023. 14. 1299792-1299792
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Yousef Salama, Satoshi Takahashi, Yuko Tsuda, Yoshio Okada, Koichi Hattori, Beate Heissig. YO2 Induces Melanoma Cell Apoptosis through p53-Mediated LRP1 Downregulation. Cancers. 2022. 15. 1. 288-288
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MISC (86)：
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Shinya Munakata, Kumpei Honjo, Yoshihiro Tashiro, Kazuhiro Sakamoto, Salama M. Yousef, Kouchi Hattori, Beate Heissig. PLASMINOGEN ACTIVATOR INHIBITOR-1 IS A THERAPEUTIC TARGET FOR THE PREVENTION OF POSTOPERATIVE ADHESION IN MICE. GASTROENTEROLOGY. 2018. 154. 6. S166-S167
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Hattori Koichi, Takahashi Satoshi, Heissig Beate. 造血ニッチにおけるアンジオクライン因子群による間葉系幹細胞増殖制御機構(Angiocrine factors expand mesenchymal stromal cells in bone marrow niche). 臨床血液. 2017. 58. 9. 1483-1483
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Shimazu Hiroshi, Munakata Shinya, Tashiro Yoshihiko, Takahashi Tsuyoshi, Nakauchi Hiromitsu, Heissig Beate, Hattori Koichi. 血球貪食症候群の病態における線溶系の機能解析(Functional analysis of the fibrinolytic system in the pathogenesis of Hemophagocytic syndrome). 臨床血液. 2017. 58. 9. 1538-1538
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Shimazu Hiroshi, Tashiro Yoshihiko, Heissig Beate, Hattori Koichi. マウスのHPS/MASの進行におけるplasminの役割(Roles of plasmin for the progression of HPS/MAS in mice). 臨床血液. 2016. 57. 9. 1658-1658
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宗像 慎也, 植山 孝恵, 牧野 有里香, 本庄 薫平, 青木 順, 高橋 里奈, 丹羽 浩一郎, 石山 隼, 杉本 起一, 神山 博彦, et al. 炎症性腸疾患におけるプロテアーゼの機能解明. 日本外科学会定期学術集会抄録集. 2016. 116回. PS-138
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Patents (4)：
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COVID-19の重症化を予測する血中バイオマーカー
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炎症性疾患治療剤
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組織プラスミノーゲン活性化因子を使用した末梢血幹細胞動員及び組織再生促進
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血管新生方法及び血管新生剤
Education (2)：
- 1993 - マールブルグ・フィリップス大学 医学部 大学院医学研究科
- 1990 - マールブルグ・フィリップス大学 医学部
Professional career (1)：
Work history (14)：
- 2021/10 - 現在 Juntendo University, Graduate School of Medicine Department of Research Support Utilizing Bioresource Bank Specially Appointed Associate Professor
- 2019/04 - 2021/09 Juntendo University Graduate School of Medicine
- 2012 - 2019/03 The University of Tokyo The Institute of Medical Science
- 2010 - The University of Tokyo The Institute of Medical Science
- 2007 - The University of Tokyo The Institute of Medical Science
- 2005 - The University of Tokyo The Institute of Medical Science
- 2004 - The University of Tokyo The Institute of Medical Science
- 2003 - Juntendo University Faculty of Medicine
- 2000 - 米国コーネル大学 医学部 リサーチアソシエイト
- 1998 - 米国スローン・ケタリング癌研究所 ポストドクトラールリサーチフェロー
- 1994 - Heidelberg University
- 1993 - ドイツ骨髄提供データ公益有限会社 医員
- 1992 - エバーハート・カールス大学 メディカルクリニック 臨床研修医
- 1991 - チュービンゲン大学 医学部附属病院 臨床研修医
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Awards (4)：
- 2020/11 - JSPS Alumni Club Award (JACA) JSPS Alumni Club Award (JACA) JSPS Alumni Club Award (JACA)
- 2004/11 - International Medical Society of Japan (IMSJ) Ishibashi Memorial Award IMSJ Ishibashi Memorial Award IMSJ
- 2003 - 米国白血病・リンパ腫協会 研究助成スペシャルフェロー
- 2003 - アレキサンダー・フォン・フンボルト財団 長期フェローシップ
Association Membership(s) (2)：
American Association for Cancer Research
, American Society of Hematology
