Research keywords (3)：
Longevity
, Aging
, Adipose tissue metabolism
Research theme for competitive and other funds (5)：
2024 - 2027 健康寿命延伸の鍵を握る脂質代謝の性差から見たマクロファージ由来NPYの役割
2024 - 2025 次世代老化制御ターゲットと作用物質の探索」に関する共同研究契約
2015 - 2019 Regulation of cancer and aging by FoxO and investigation of compounds for regulation of FoxO
2015 - 2018 Establishment of anti-aging mechanisms by NPY in the fat metabolism
2017 - 2018 Financial Support for Overseas Travel Expenses of Medical Scholars from Japan
Papers (37)：
Seongjoon Park, Isao Shimokawa. Influence of Adipokines on Metabolic Dysfunction and Aging. Biomedicines. 2024. 12. 873
Seongjoon Park, Toshimitsu Komatsu, Hiroko Hayashi, Ryoichi Mori, Isao Shimokawa. The Role of Neuropeptide Y in Adipocyte-Macrophage Crosstalk during High Fat Diet-Induced Adipose Inflammation and Liver Steatosis. Biomedicines. 2021. 9. 11. 1739-1739
Park S, Nayantai E, Komatsu T, Hayashi H, Mori R, Shimokawa I. NPY deficiency prevents postmenopausal adiposity by augmenting estradiol-mediated browning. The journals of gerontology. Series A, Biological sciences and medical sciences. 2020. 75. 6. 1042-1049
Zi Wang, Toshimitsu Komatsu, Yoshihisa Ohata, Yukari Watanabe, Yiwen Yuan, Yuki Yoshii, Seongjoon Park, Ryoichi Mori, Motoyasu Satou, Yoshitaka Kondo, et al. Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. Geriatrics Gerontology International. 2019. 1-10
Komatsu T, Park S, Hayashi H, Mori R, Yamaza H, Shimokawa I. Mechanisms of Calorie Restriction: A Review of Genes Required for the life-Extending and Tumor-Inhibiting Effects of calorie Restriction. Nutrients. 2019
Roy G. Smith, Andras Kern, Nicole H. Rogers, Heidi Walsh, Rosie Albarran-Zeckler, Bryan Wharram, Seongjoon Park. Ghrelin and its receptor (GHS-R): Recent progress. ENDOCRINE JOURNAL. 2010. 57. S229-S229
Books (2)：
Aging and Nutrition
2018
Aging Mechanisms; Longevity, Metabolism, and Brain Aging; Role of the Forkhead Box O Family and Neuropeptide Y in Calorie Restriction.
Springer 2015
Lectures and oral presentations (14)：
The emerging role of ZFP90-mediated immunometabolism in the obesity related non-alcoholic fatty liver disease.
(The Pusan-Nagasaki Joint Symposium on Aging Research, 2023)
Critical role of NPY in the lipid metabolic homeostasis under negative energy balance
(Würzburg-Nagasaki Digital Seasonal Symposium 2021, ‘Healthy aging’ 2021)
ZFP90 as a multitasking player in the protection of obesity related non-alcoholic fatty liver disease.
(The 44th Annual Congress of the Japan Society for Biomedical Gerontology 2021)
Deletion of ZFP90 accelerates high fat diet-induced fatty liver.
(The 110th Annual Congress of the Japanese Society of Pathology 2021)
Regulation of fat utilization and adiposity by NPY deficiency in female mice.
(The 42th Annual Congress of the Japan Society for Biomedical Gerontology 2019)
