Rchr
J-GLOBAL ID：201801004200866731
Update date: Mar. 19, 2024
Hasegawa Atsushi
ハセガワ アツシ | Hasegawa Atsushi
Affiliation and department：
Job title：
Researcher
Homepage URL (1)：
https://www.megabank.tohoku.ac.jp/tommo/member/member04
Research field (2)：
Hematology and oncology
, Medical biochemistry
Research keywords (4)：
バイオバンク
, 造血
, GATA2
, GATA1
Research theme for competitive and other funds (6)：
Papers (14)：
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Daishi Ishihara, Atsushi Hasegawa, Ikuo Hirano, James Douglas Engel, Masayuki Yamamoto, Ritsuko Shimizu. The abundance of the short GATA1 isoform affects megakaryocyte differentiation and leukemic predisposition in mice. Experimental Hematology & Oncology. 2024. 13. 1
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Yu-Ichi Aoki, Keiko Taguchi, Hayato Anzawa, Junko Kawashima, Noriko Ishida, Akihito Otuki, Atsushi Hasegawa, Liam Baird, Takafumi Suzuki, Ikuko N Motoike, et al. Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals. Journal of biochemistry. 2024
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Ritsuko Shimizu, Ikuo Hirano, Atsushi Hasegawa, Mikiko Suzuki, Akihito Otsuki, Keiko Taguchi, Fumiki Katsuoka, Akira Uruno, Norio Suzuki, Akane Yumoto, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Communications Biology. 2023. 6. 1. 875
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Atsushi Hasegawa, Yuki Hayasaka, Masanobu Morita, Yuta Takenaka, Yuna Hosaka, Ikuo Hirano, Masayuki Yamamoto, Ritsuko Shimizu. Heterozygous variants in GATA2 contribute to DCML deficiency in mice by disrupting tandem protein binding. Communications Biology. 2022. 5. 1. 376-376
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Shun-suke Sakai, Atsushi Hasegawa, Ryosuke Ishimura, Naoki Tamura, Shun Kageyama, Satoko Komatsu-Hirota, Manabu Abe, Yiwei Ling, Shujiro Okuda, Manabu Funayama, et al. Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size. Molecular and Cellular Biology. 2022. 42. 1. e0002421
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MISC (4)：
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長谷川 敦史, 清水 律子. 赤血球造血におけるGATA1研究の新たな展開. 血液内科. 2016. 73. 2. 221-227
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Atsushi Hasegawa, Hiroshi Kaneko, Daishi Ishihara, Masahiro Nakamura, Akira Watanabe, Cecelia D. Trainor, Yamamoto Masayuki, Ritsuko Shimizu. GATA1 Changes DNA-Binding Fashion in a Binding-Site-Specific Manner and Alters Transcriptional Activity during Erythropoiesis. BLOOD. 2015. 126. 23
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Atsushi Hasegawa, Ritsuko Shimizu, Hirofumi Kurokawa, Masayuki Yamamoto. DNA Binding Diversity Achieved Through the Interaction of GATA1 N-Finger and GATA Motif Is Important for Embryonic Erythropoiesis. BLOOD. 2012. 120. 21
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Ritsuko Shimizu, Atsushi Hasegawa, Masayuki Yamamoto. Spherocytic Hemolytic Anemia Caused by Disruption of GATA1-FOG1 Interaction. BLOOD. 2009. 114. 22. 321-321
Books (2)：
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最新醫學・別冊 診断と治療のABC 「貧血症」
最新医学社 2017
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血液内科
科学評論社 2016
Lectures and oral presentations (20)：
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変異タンパク質によるGATA2の機能障害が惹起する免疫細胞産生異常
(第26回造血器腫瘍研究会 2022)
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GATA2変異が引き起こす細胞機能の変化
(第87回日本生化学会 東北支部会・シンポジウム 2021)
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GATA2による系列特異的な免疫細胞産生制御
(第92回日本生化学会大会 2019)
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GATA2による系列特異的な免疫細胞産生制御
(第91回日本生化学会大会 2018)
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GATA2変異導入によるDCML欠損症モデルマウスの樹立と疾患発症機序解析
(第22回造血器腫瘍研究会 2018)
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Education (3)：
- 2010 - 2014 Tohoku University Graduate School of Medicine Department of Medical Sciences
- 2008 - 2010 Tohoku University Graduate School of Medicine Department of Medical Sciences
- 2004 - 2008 University of Tsukuba
Professional career (1)：
Work history (4)：
- 2022/04 - 現在 Tohoku University Tohoku Medical Megabank Organization Department of Biobank Researcher
- 2019/04 - 2022/03 Tohoku University Graduate School of Medicine
- 2017/10 - 2019/03 Tohoku University Organization for Academic Activity Support
- 2014/04 - 2017/09 Tohoku University
Awards (3)：
- 2017/05 - 日本生化学会東北支部 日本生化学会東北支部 優秀論文賞
- 2013/01 - 東北医学会 平成24年度 東北医学会奨学賞(B)
- 2010/07 - 日本血液学会 Young Investigator Award
Association Membership(s) (2)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE BIOCHEMICAL SOCIETY
