2020 - 2023 Molecualr imaging for development of chimeric antigen receptors (CARs) resistant to T cell exhaustion
2018 - 2021 細胞膜構造ダイナミクスによるT細胞抗原受容シグナルの時空間的制御機構
2017 - 2020 Basic research for the development of a novel CAR-adaptor T cells by an advanced imaging system
2015 - 2018 CD4陽性T細胞の確率的な活性化によって制御される抗原特異的な細胞増殖
Well of the well法を用いた免疫細胞の新規培養法の確立
免疫T細胞の分化を光制御するシステムの開発
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Papers (39):
Ei Wakamatsu, Hiroaki Machiyama, Hiroko Toyota, Arata Takeuchi, Ryuji Hashimoto, Haruo Kozono, Tadashi Yokosuka. Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II. Cell reports. 2024. 114655-114655