Yoshida Takashi

Affiliation and department：
Job title：准教授

Research field (1)： Cell biology

Research theme for competitive and other funds (9)：

2023 - 2026 近赤外光活性化人工チャネルの創生による抗がん治療法の開発
2020 - 2025 細胞種ごとに異なる発現パターンを示す小胞体内イオン輸送体の生理学的意義の解明
2018 - 2023 The development of regulatory methods for osteocyte function using optogenetics
2015 - 2018 The development of light-activatable proteins for inducing mechanical stimulation in the cells
2015 - 2018 Pathophysiological analysis of oral diseases caused by dysregulation of cation channels

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Papers (19)：

Shinichiro Yamamoto, Naoto Kiyatake, Akihiro Kaneko, Masanao Shimamura, Takashi Yoshida, Shunichi Shimizu. Mouse transient receptor potential melastatin 2 (TRPM2) isoform 7 attenuates full-length mouse TRPM2 activity through reductions in its expression by targeting it to ER-associated degradation. Genes to cells : devoted to molecular & cellular mechanisms. 2024
Kaori Takahashi, Takashi Yoshida, Minoru Wakamori. Periodontal Ligaments Enhance Neurite Outgrowth in Trigeminal Ganglion Neurons through Wnt5a Production Induced by Mechanical Stimulation. American Journal of Physiology-Cell Physiology. 2022
Chenyao Wang, Shin-ichiro Horigane, Minoru Wakamori, Shuhei Ueda, Takeshi Kawabata, Hajime Fujii, Itaru Kushima, Hiroki Kimura, Kanako Ishizuka, Yukako Nakamura, et al. Identification of ultra-rare disruptive variants in voltage-gated calcium channel-encoding genes in Japanese samples of schizophrenia and autism spectrum disorder. Translational Psychiatry. 2022. 12. 1
Masayuki Izumi, Takashi Yoshida, Takashi Nakamura, And Minoru Wakamori. Paeonol, an Ingredient of Kamishoyosan, Reduces Intracellular Lipid Accumulation by Inhibiting Glucocorticoid Receptor Activity in 3T3-L1 Cells. Nutrients. 2020. 12. 2
Ryo Shinotsuka, Toru Oba, Takahiro Mitome, Takuto Masuya, Satoshi Ito, Yukie Murakami, Tomoko Kagenishi, Yutaka Kodama, Masaru Matsuda, Takashi Yoshida, et al. Synthesis of quinolyl-pyrrole derivatives as novel environment-sensitive fluorescent probes. Journal of Photochemistry and Photobiology A: Chemistry. 2019. 382. 111900-111900

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MISC (17)：

Takashi Yoshida, Kaori Takahashi, Minoru Wakamori. The inhibitory mechanism of eugenol on TRPV1 channel. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 175P-175P
Takashi Yoshida, Kaori Takahashi, Takashi Kikuchi, Minoru Wakamori. The inhibitory mechanism of eugenol on TRPV1 channel. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 171P-171P
Nobuaki Takahashi, Takashi Yoshida, Shinichiro Yamamoto, Yoshifumi Ueda, Yasuo Mori. Spatio-temporal regulation of intracellular Ca2+ and NO signaling by the TRPC5 channel complex. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S196-S196
Takashi Yoshida, Takashi Kikuchi, Kaori Takahashi, Minoru Wakamori. The conflicting effects of eugenol on TRPV1 channel. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 249P-249P
Takashi Yoshida, Minoru Wakamori. TRP channels play a role in the mouse osteoblast cell line MC3T3-E1 under shear stress. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 220P-220P

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Lectures and oral presentations (15)：

一酸化窒素のシステイン残基直接酸化修飾によるTRPチャネル活性化機構
(第49回歯科基礎医学会学術大会 2007)
一酸化窒素によるニトロシル化を介したTRP チャンネル活性化
(第84回日本生理学会大会 2007)
NOによるニトロシル化を介したTRPチャネル活性化とそのシグナル統合における意義
(細胞シグナリングの時空間統御機構解明への方略探索 2006)
Nitric-oxide directly activates TRP channels via oxidative cysteine modification
(20th IUBMB International Congress of Biochemistry and Molecular biology 2006)
TRPチャネル拮抗剤による新規修飾方法の開発
(第2回TRPチャネル研究会 2006)

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