Rchr
J-GLOBAL ID：201801004413235794   Update date: Jan. 31, 2024

Tomoaki Sato

Tomoaki Sato
Affiliation and department：
鹿児島大学大学院 医歯学総合研究科 歯科応用薬理学分野

About 鹿児島大学大学院 医歯学総合研究科 歯科応用薬理学分野


Job title： 教授
Research field  (3)： Oral medicine ,  Pharmacology ,  Neuroscience - general
Research theme for competitive and other funds  (16)：
  • 2022 - 2025 がん細胞における放射線抵抗性の可逆性を利用した放射線抵抗性因子の総合的探索
  • 2022 - 2025 ミトコンドリアを標的としたフェロトーシス誘導による治療抵抗性がん克服への挑戦
  • 2021 - 2025 アクアポリンを制御するミトコンドリア移植法による新しい歯髄保存・再生療法の開発
  • 2019 - 2022 Long-term live cell imaging to overcome radioresistant cancer cells.
  • 2019 - 2022 Crosstalk between lipid peroxidation of the plasma membrane and intracellular organelles that control radiation and drug resistance
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Papers (102)：
  • Kazuo Tomita, Yoshikazu Kuwahara, Kento Igarashi, Junichi Kitanaka, Nobue Kitanaka, Yuko Takashi, Koh-ichi Tanaka, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Akihiro Kurimasa, et al. Therapeutic potential for KCC2-targeted neurological diseases. Japanese Dental Science Review. 2023. 59. 431-438
  • Kazuo Tomita, Yukiko Oohara, Kento Igarashi, Junichi Kitanaka, Nobue Kitanaka, Koh-ichi Tanaka, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Mitsutaka Sugimura, Tomoaki Sato. Kamishoyosan and Kamikihito protect against decreased KCC2 expression via neuroinflammation induced by the P. gingivalis lipopolysaccharide treatment in PC-12 cells and improve behavioral abnormalities in male mice. Heliyon. 2023. 9. 12. e22784
  • Amirsadegh Nikoo, Mehryar Habibi Roudkenar, Tomoaki Sato, Yoshikazu Kuwahara, Kazuo Tomita, Zahra Pourmohammadi-Bejarpasi, Nima Najafi-Ghalehlou, Amaneh Mohammadi Roushandeh. Mitochondrial transfer in PC-3 cells fingerprinted in ferroptosis sensitivity: a brand new approach targeting cancer metabolism. Human Cell. 2023
  • Yoshikazu Kuwahara, Kazuo Tomita, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Tomoaki Sato, Akihiro Kurimasa. The reversibility of cancer radioresistance: a novel potential way to identify factors contributing to tumor radioresistance. Human Cell. 2023
  • Glycogen synthase kinase-3 inhibitors block morphine-induced locomotor activation, Straub tail, and depression of rearing in mice via a possible central action. 2023. doi: 10.1007/s11064-023-03902-2
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MISC (48)：
  • Kazuo Tomita, Yoshikazu Kuwahara, Kento Igarashi, Akihiro Kurimasa, Manabu Fukumoto, Tomoaki Sato. Intracellular Fe2+regulates oxidative stress resistance. CANCER SCIENCE. 2021. 112. 576-576
  • Kazuo Tomita, Kento Igarashi, Tomoaki Sato. Effect on mitochondria by periodontal disease-derived LPS treatment in PC-12 cell. 2021
  • Tomita K, Takashi Y, Igarashi K, Nishitani Y, Sato T. CRR Cells Show Resistance to H2O2 as a Delay in Timing of the Endogenous H2O2 Increase and of Lipid Peroxidation Increase. J. Oral Biosci. 2018. supple. 158
  • Tomita K, Kuwahara Y, Takashi Y, Yamanishi S, Nabika H, Tanaka K, Kitanaka J, Kitanaka N, Takemura M, Nishiyama N, et al. Analysis of oxidative stress response in clinically relevant radioresistant cells. 18th World Congress of Basic and Clinical Pharmacology. 2018
  • Furukawa M, Tsukahara T, Tomita k, Miyawaki S, Sato T. The influence of stress on higher brain function in early life. The Journal of Japanese Society of Stomatognathic Function. 2017. 24. 1. 28-29
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Books (6)：
  • 歯科漢方医学
    末永書店 2018
  • 現代歯科薬理学(第6版)
    医歯薬出版 2018
  • 現代歯科薬理学(第5版)
    医歯薬出版 2011
  • 歯科薬理学(第5版)
    医歯薬出版 2005
  • 先端医療シリーズ・歯科医学2 歯周病〜新しい治療を求めて〜
    先端医療技術研究所 2000
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Lectures and oral presentations  (26)：
  • KCC2, a K+-Cl- co-transporter, is a possible target to attenuate the neuronal dysfunction that is associated with radiation therapy for brain tumor
    (2019)
  • miR-7-5pは細胞内Fe2+抑制を介して放射線抵抗性を制御する
    (第21回応用薬理学シンポジウム(静岡、発表予定) 2019)
  • Analysis of hydrogen peroxide resistance mechanism on hydrogen peroxide resistant cancer cells.
    (2019)
  • Effects of purine and pyrimidine nucleosides on hydrogen peroxide-induced thymidine incorporation
    (2019)
  • Tetrabenazine attenuates morphine-induced hyperlocomotion, but not antinociception, in mice
    (日本薬理学会年会(大阪) 2019)
ｍore...
Professional career (1)：
  • 博士(歯学) (鹿児島大学)
Work history (5)：
  • 2007/09 - 現在 Kagoshima University Graduate School Department of Applied Pharmacology Professor
  • 2006 - Kagoshima University Graduate School of Medical and Dental Sciences
  • 2003 - 鹿児島大学 医歯学総合研究科 歯科応用薬理学分野 助教授
  • 2002/05 - Kagoshima University Dental School
  • 1996/04 - Kagoshima University Dental School
Committee career (3)：
  • 2018/05 - 現在 歯科基礎医学会 代議員
  • - 現在 日本薬理学会 代議員
  • 2011/04 - 2014/03 歯科基礎医学会 理事
Association Membership(s) (6)：
THE JAPANESE CANCER ASSOCIATION ,  JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY ,  JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  THE JAPAN SOCIETY FOR ORIENTAL MEDICINE
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