Research theme for competitive and other funds (44)：
2022 - 2025 脳発達期の脂肪酸栄養が発達障害の発症増悪に与える影響
2022 - 2025 Molecular mechanism underlying immune cell responses regulated by lipid intake during development
2020 - 2025 Significance of lipid nutrition in the pathological mechanisms of neurodegenerative and psychiatric diseases
2020 - 2023 胎児期からの脂肪酸摂取バランスが炎症性腸疾患の寛解と再燃に与える影響
2020 - 2022 Exploration of cancer cell microenvironment network focusing on the adipocytes
2019 - 2022 Molecular basis of neural cell response to the nutritional intake of fatty acids during development
2019 - 2022 Elucidation of epigenome regulation mechanism by fatty acid binding protein
2018 - 2020 ω6長鎖脂肪酸を介した神経炎症制御に対して脂肪酸結合蛋白質が果たす役割
2018 - 2020 Exploring the new regulatory mechanism underlying hypothalamic capillary dynamics
2017 - 2020 Control of obesity and inflammatory bowel disease by polyunsaturated fatty acid adjusted diet
2016 - 2019 Significance of lipid metabolism in glial cell function: association with psychiatiric diseases
2016 - 2019 Fatty acid binding protein in the anterior cingulate cortex modulates GABAergic system
2016 - 2018 Role of glia in hypothalamic nutrient sensing
2016 - 2018 Novel mechanism how hypothalamus senses the lipid of the blood.
2014 - 2018 Genome epidemiological study on sleep and mental health
2014 - 2017 Effects of fatty acids on the obese patients suffered from inflammatory bowel disease and development of examination of feces
2014 - 2016 Fatty acid binding protein regulates higher brain function via lipid metabolism regulation
2012 - 2016 Molecular basis and physiological function of cellular lipid homeostasis in the brain and immune stromal cells
2013 - 2015 Possiblity of fatty acid binding protein as a diagnostic and therapeutic target in glioma
2012 - 2015 Effects of lipids on the function of thymic epithelial cells
2012 - 2014 Role of fatty acid binding proteins for regulation of neural plasticity
2011 - 2013 Influence of maternal intake of n-3 fatty acid on fatty acid transport of fetal blood brain barrier
2010 - 2012 Application of focal brain cooling for intractable epilepsy
2010 - 2012 Epidermal fatty acid binding protein (EFAP/FABP5) expression is associated with differential transcytosis of M cells in C57BL/6 mice Peyer's patch
2009 - 2011 Mechanism by which fatty acid binding proteins regulate the cellular signal transduction
2008 - 2011 Identification of Epileptogenic Focus by Employing Softcomputing and Establishment of Minimally Invasive and Definitive Surgery
2008 - 2010 Analysis of functional significance of lipids in receptors for vision, hearing and olfaction by way of functional analysis of fatty acid binding proteins
2008 - 2010 Analysis of B-FABP as an immunoregulatory factor by modulating omega-3 polyunsaturated fatty acid metabolism
2007 - 2008 A role of fatty acid binding protein as a regulator of cellular functions
2006 - 2007 Analysis of Novel Cellular Functions of Fatty Acid Binding Proteins
2005 - 2006 Function analysis of fatty acid binding protein in the immune cells
2005 - 2006 Differentiation disturbance in keratinocytes lacking the epidermal fatty acid binding protein gene (E-FABP) which is overexpressed in psoriatic lesions.
2002 - 2003 Functional analysis of fatty acid binding proteins in immune and neural tissues.
2002 - 2003 Functional analysis of fatty acid binding proteins in the brain
2002 - 2003 神経疾患バイオセンサーとしての脂肪酸結合タンパクの可能性追及
2000 - 2001 海馬シナプス可塑性調節および神経細胞死における脂肪酸結合蛋白の機能追及
1999 - 2000 Molecular and Cell Biological Analysis of lipid kinases and phosphatases involved in phosphoinosilide signaling
1999 - 2000 Molecular and Celluler Biological Analysis of the functional Significance of Phosphoinositide Metabolism
1997 - 1998 The regulation mechanism of lipid kinase in the signal transduction
1997 - 1998 Molecular and Cell Biological Analysis of Lipid Kinases in Relation to Signaling and Vesicle Traffic.
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Papers (194)：
Suda A, Umaru BA, Yamamoto Y, Shima H, Saiki Y, Pan Y, Jin L, Sun J, Low YLC, Suzuki C, et al. Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth. Scientific reports. 2024
Jun Suzuki, Tomotaka Hemmi, Masamitsu Maekawa, Masahiro Watanabe, Hitoshi Inada, Hiroyuki Ikushima, Tetsuya Oishi, Ryoukichi Ikeda, Yohei Honkura, Yoshiteru Kagawa, et al. Fatty acid binding protein type 7 deficiency preserves auditory function in noise-exposed mice. Scientific reports. 2023. 13. 1. 21494-21494
Takashi MaruYama, Hirofumi Miyazaki, Taishi Komori, Shion Osana, Hiroyuki Shibata, Yuji Owada, Shuhei Kobayashi. Curcumin analog GO-Y030 inhibits tumor metastasis and glycolysis. The Journal of Biochemistry. 2023
Tomotaka Hemmi, Jun Suzuki, Yoshiteru Kagawa, Yohei Honkura, Ryoukichi Ikeda, Ken Hashimoto, Chitose Suzuki, Tetsuaki Kawase, Takaaki Abe, Yuji Owada, et al. Effects of Ndufs4 Deletion on Hearing after Various Acoustic Exposures. The Tohoku journal of experimental medicine. 2023
MaruYama T, Miyazaki H, Lim YJ, Gu J, Ishikawa M, Yoshida T, Chen W, Owada Y, Shibata H. Pyrolyzed Deketene Curcumin Controls Regulatory T Cell Generation and Gastric Cancer Metabolism Cooperate With 2-Deoxy-D-Glucose. Frontiers in Immunology (T Cell Biology). 2023. In press
FABP7 protects astrocyte against ROS toxicity under ROS stress
(第123回日本解剖学会総会 2018)
FABP3 in the anterior cingulate cortex mediates methylation status of gluatamic acid decarboxylase 67 promoter region.
(18th World Congress of Basic and Clinical Pharmacology 2018)
Role of FABP7 in astrocytes and its possibe association with psychiatric diseases.
(59th International Symposium on "Biological Regulation and Enzyme Activity in Normal and Neoplastic Tissues" Symposium "Signaling and Disease" 2018)
- 1997 Tohoku University Graduate School of Medicine
- 1989 Tohoku University Faculty of Medicine School of Medicine
Professional career (1)：
博士(医学) (東北大学)
Work history (5)：
2015 - 現在 Tohoku University
2006 - 2014 Yamaguchi University
2002 - 2006 Tohoku University
2000 - 2002 Tohoku University
1997 - 1999 Tohoku University
Awards (3)：
2007 - 宇部興産学術振興財団 学術奨励賞 FABP分子の神経系における機能調節機構の解析
1999 - 東北医学会 奨励賞 脳における脂肪酸結合タンパク質の発現と機能
1999 - 日本解剖学会 奨励賞 脂肪酸結合蛋白質の組織発現・機能解析
Association Membership(s) (6)：
JAPAN BRAIN SCIENCE SOCIETY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY
, 米国神経科学会
, THE JAPANESE ASSOCIATION OF ANATOMISTS
, 日本神経科学会
