Rchr
J-GLOBAL ID：201801004449082439   Update date: Sep. 17, 2024

OIKAWA Tsunekazu

オイカワ ツネカズ | OIKAWA Tsunekazu
Affiliation and department：
The Jikei University School of Medicine Department of Internal Medicine, Division of Gastroenterology and Hepatology

About The Jikei University School of Medicine Department of Internal Medicine, Division of Gastroenterology and Hepatology


Research field  (2)： Gastroenterology ,  Cell biology
Research keywords  (5)： バイオマーカー ,  肝癌 ,  幹細胞 ,  肝再生 ,  肝疾患
Research theme for competitive and other funds  (8)：
  • 2023 - 2025 新規タンパク質分泌機構CUPSを標的としたがん治療薬の研究開発
  • 2022 - 2025 肝癌特異的な細胞外分泌蛋白を用いた新規早期診断法確立とその実用化に向けた検証研究
  • 2021 - 2024 早期肝がんに対するPKCδ を用いた新規高感度診断法の開発
  • 2019 - 2022 Gene therapy development in liver cancer
  • 2016 - 2019 The role of DYRK2 in primary liver cancers
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Papers (60)：
  • Norio Itokawa, Masanori Atsukawa, Akihito Tsubota, Toru Ishikawa, Hidenori Toyoda, Koichi Takaguchi, Tsunamasa Watanabe, Chikara Ogawa, Atsushi Hiraoka, Hironao Okubo, et al. Kinetics of the hepatitis B core-related antigen and treatment responses in chronic hepatitis B patients treated with tenofovir alafenamide. Hepatology research : the official journal of the Japan Society of Hepatology. 2024
  • Chika Nakagawa, Tsunekazu Oikawa, Kohji Yamada, Akihito Tsubota, Chisato Saeki, Kuniko Katagiri, Naoko Tago, Hiroshi Kamioka, Kaoru Ueda, Koichiro Haruki, et al. Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2024. 1-13
  • Takashi Aida, Koichiro Haruki, Munetoshi Akaoka, Kenei Furukawa, Shinji Onda, Yoshihiro Shirai, Hironori Shiozaki, Keita Takahashi, Tsunekazu Oikawa, Toru Ikegami. A novel combined C-reactive protein-albumin ratio and modified albumin-bilirubin score can predict long-term outcomes in patients with hepatocellular carcinoma after hepatic resection. Annals of gastroenterological surgery. 2024. 8. 1. 143-150
  • Chisato Saeki, Tomoya Kanai, Kaoru Ueda, Masanori Nakano, Tsunekazu Oikawa, Yuichi Torisu, Masayuki Saruta, Akihito Tsubota. Insulin-like growth factor 1 predicts decompensation and long-term prognosis in patients with compensated cirrhosis. Frontiers in Medicine. 2023. 10
  • Hiroshi Kamioka, Satomi Yogosawa, Tsunekazu Oikawa, Daisuke Aizawa, Kaoru Ueda, Chisato Saeki, Koichiro Haruki, Masayuki Shimoda, Toru Ikegami, Yuji Nishikawa, et al. Dyrk2 gene transfer suppresses hepatocarcinogenesis by promoting the degradation of Myc and Hras. JHEP reports : innovation in hepatology. 2023. 5. 7. 100759-100759
ｍore...
MISC (8)：
  • 及川恒一, 山田幸司, 坪田昭人, 佐伯千里, 上田薫, 神岡洋, 春木孝一郎, 池上徹, 吉田清嗣, 猿田雅之. 早期診断に有用な肝細胞癌特異的バイオマーカー血清PKCδ. 肝細胞研究会プログラム・抄録集. 2023. 30th
  • 横山 寛, 政木 隆博, 井上 育代, 中村 まり子, 目崎 喜弘, 佐伯 千里, 及川 恒一, 猿田 雅之, 鷹橋 浩幸, 池上 雅博, et al. 慢性肝疾患患者におけるTGF-β活性化の組織学的・血液生化学的評価と臨床的意義. 東京慈恵会医科大学雑誌. 2019. 134. 6. 110-110
  • Shinya Fukunishi, Keisuke Yokohama, Akira Asai, Kazuhide Higuchi, Toshihide Shima, Takeshi Okanoue, Takuya Genda, Yoshio Aizawa, Tsunekazu Oikawa, Yoshihiro Matsumoto, et al. EFFICACY AND SAFETY OF GLECAPREVIR/PIBRENTASVIR IN PATIENTS WITH SEVERE RENAL IMPAIRMENT IN JAPAN: A PROSPECTIVE, MULTICENTER STUDY (KTK 49 LIVER STUDY GROUP). HEPATOLOGY. 2019. 70. 960A-961A
  • Tsunekazu Oikawa, Akihide Kamiya, Mikio Zeniya, Hirokazu Nishino, Hiromitsu Nakauchi, Hisao Tajiri. SALL4, A STEM CELL FACTOR, CONTRIBUTES TO THE TUMOR GROWTH IN HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2011. 54. 448A-448A
  • Tsunekazu Oikawa, Akihide Kamiya, Mikio Zeniya, Hirokazu Nishino, Hiromitsu Nakauchi, Hisao Tajiri. DOWN-REGULATION OF SALL4 INHIBITS TUMOR GROWTH IN HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2010. 52. 4. 976A-977A
ｍore...
Patents (1)：
  • Human Fibrolamellar Hepatocellular Carcinomas (hFL-HCCs)
Books (2)：
  • 幹細胞マーカーSALL4における肝癌治療法の可能性
    肝胆膵 2014
  • Stem Cell Populations Giving Rise to Liver, Biliary Tree and Pancreas.
    A book chapter in Stem cells Handbook, 2nd Edition. Stewart Sell editor, Springer Science+Business Media, New York, NY. 2013
Professional career (1)：
  • M.D., Ph.D. (Jikei University School of Medicine)
Work history (5)：
  • 2023/11 - 現在 The Jikei University School of Medicine Department of Internal Medicine, Division of Gastroenterology and Hepatology Associate professor
  • 2017/04 - 2023/10 The Jikei University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant professor
  • 2015/04 - 2017/03 The Jikei University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine, Assistant professor
  • 2011/09 - 2015/03 University of North Carolina School of Medicine at Chapel Hill Department of Cell Biology and Physiology, Postdoctral Research Associate
  • 2007/06 - 2008/03 The Institute of Medical Science, University of Tokyo Division of Stem Cell Therapy, Center for Stem Cell and Regenerative Medicine, Research Fellow
Awards (6)：
  • 2014 - 公益財団法人上原記念生命科学財団 上原海外留学助成金リサーチフェローシップ
  • 2013/11 - 64th Annual Meeting of the American Association for the Study of Liver Diseases. Professor Margit Hamosh Memorial Travel Award.
  • 2013/11 - 64th Annual Meeting of the American Association for the Study of Liver Diseases. Presidential Poster of Distinction.
  • 2013/10 - 日本肝臓学会 冠アワード 第4回Bristol Myers Award
  • 2013/05 - University of North Carolina Lineberger Annual Scientific Retreat. Award Second Prize for Best Posters.
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