Ken Suzuki

スズキケン | Ken Suzuki

Affiliation and department：
Job title： Research Fellow

Research field (2)： Medical biochemistry , Systems genomics

Research keywords (5)：計算生物学 , システムバイオロジー , バイオインフォマティクス , 機械学習 , 遺伝統計学

Research theme for competitive and other funds (3)：

2021 - 2024 健診・ゲノムデータを統合したテーラーメイド型ヘルスプロモーションシステムの開発
2019 - 2021 Risk stratification and subtype classification of type 2 diabetes from disease genome by machine learning
2019 - 2021 層別化polygenic risk scoreによる形質・疾患構造の解明

Papers (35)：

Takayoshi Sasako, Ken Suzuki, Sara Odawara, Hirotsugu Suwanai, Naoko Akuta, Naoto Kubota, Kohjiro Ueki, Takashi Kadowaki, Toshimasa Yamauchi. Corticosteroid-triggered acute skeletal muscle loss in lipodystrophy: A case report. Journal of diabetes investigation. 2024
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Kim M Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Giorgio E M Melloni, Stavroula Kanoni, et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. 2024
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Kim M Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Nigel W Rayner, Ozvan Bocher, et al. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. medRxiv : the preprint server for health sciences. 2023
Yoshihiko Tomofuji, Ken Suzuki, Toshihiro Kishikawa, Nobuhiro Shojima, Jun Hosoe, Kyoko Inagaki, Sunao Matsubayashi, Hisamitsu Ishihara, Hirotaka Watada, Yasushi Ishigaki, et al. Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes. Communications Medicine. 2023. 3. 1. 5-5
Kyuto Sonehara, Yui Kimura, Yoshiko Nakano, Tatsuya Ozawa, Meiko Takahashi, Ken Suzuki, Takashi Fujii, Yuko Matsushita, Arata Tomiyama, Toshihiro Kishikawa, et al. A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors. Nature Communications. 2022. 13. 1. 4478-4478

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MISC (5)：

鈴木顕, 秋山雅人, 石垣和慶, 金井仁弘, 細江隼, 庄嶋伸浩, 池川志郎, 寳澤篤, 山本雅之, 門田文, et al. 大規模ゲノム解析による28の新規2型糖尿病感受性領域の同定. 日本肥満学会・日本肥満症治療学会合同学術集会プログラム・抄録集. 2019. 40th-37th
Jun Hosoe, Hiroko Kadowaki, Fuyuki Miya, Katsuya Aizu, Ichiro Miyata, Tomoyuki Kawamura, Kenichi Satomura, Takeru Ito, Ken Suzuki, Tat-Suhiko Tsunoda, et al. Severe Insulin Resistance Caused by Mutations in INSR: Genotype-Phenotype Correlations and Structural Characterization of the Mutations. DIABETES. 2017. 66. A370-A370
Yuta Hiraike, Hironori Waki, Jing Yu, Masahiro Nakamura, Kana Miyake, Ken Suzuki, Ryo Nakaki, Gaku Nagano, Haruya Ohno, Kenji Oki, et al. NFIA Controls the Brown Fat Gene Program by Colocalizing with PPARgamma at Cell-Type-Specific Enhancers. DIABETES. 2017. 66. A67-A67
細江隼, 門脇弘子, 宮冬樹, 会津克哉, 宮田市郎, 川村智行, 里村憲一, 鈴木顕, 高倉美菜香, 角田達彦, et al. インスリン受容体遺伝子変異に関するタンパク質立体構造への影響と表現型の相関(structure-phenotype correlation). 糖尿病(Web). 2017. 60. Suppl
Yuta Hiraike, Hironori Waki, Jing Yu, Masahiro Nakamura, Kana Miyake, Ken Suzuki, Ryo Nakaki, Wei Sun, Tomohisa Aoyama, Yusuke Hirota, et al. NFIA Controls the Brown Fat Gene Program by Co-Localizing with PPARgamma at Cell Type-Specific Enhancers. DIABETES. 2016. 65. A441-A441

Books (6)：

Medical Practice
2020
内分泌・糖尿病・代謝内科特集/糖尿病・肥満症に対するPrecision Medicine実現に向けて
科学評論社 2019
DIABETES UPDATE
メディカルレビュー社 2019
糖尿病学2019
診断と治療社 2019
日本体質医学会雑誌
2019

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Lectures and oral presentations (16)：

糖尿病発症予測への感受性遺伝子の応用
(第56回糖尿病学の進歩 2022)
2型糖尿病の遺伝因子を探求する
(第6回日本糖尿病・生活習慣病ヒューマンデータ学会 2021)
日本のバイオバンク・コホートを活用した2型糖尿病ゲノム研究と国際共同研究の展開
(日本人類遺伝学会第66回大会 2021)
Progress in genetic research of type 2 diabetes and polygenic risk scores in Japan
(International Congress of Diabetes and Metabolism 2021 2021)
糖尿病ゲノム研究の最近の動向
(第64回日本糖尿病学会年次学術集会 2021)

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Education (3)：

2012 - 2018 The University of Tokyo
2006 - 2010 The University of Tokyo Faculty of Medicine School of Medicine
2004 - 2006 The University of Tokyo College of Arts and Sciences

Professional career (1)：

博士(医学) (東京大学大学院)

Work history (8)：

2021/10 - 現在 The University of Manchester Research Fellow
2021/10 - 現在日本学術振興会海外特別研究員
2018/10 - 2021/09 Osaka University Graduate School of Medicine
2018/04 - 2018/09 Osaka University Graduate School of Medicine
2013/04 - 2018/03 東京大学医学部附属病院糖尿病・代謝内科診療医

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Awards (14)：

2023/04 - 日本医学会総会最優秀奨励賞(内科系)
2022/02 - 井上科学振興財団井上研究奨励賞
2021/10 - Asian Association for the Study of Diabetes AASD Presentation Grant
2020/11 - 日本医師会医学研究奨励賞
2020/05 - 大阪大学未来基金【住野勇財団】学部学生による自主研究奨励事業優秀賞

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Association Membership(s) (4)：

The American Society of Human Genetics , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , THE JAPAN SOCIETY OF HUMAN GENETICS , THE JAPAN DIABETES SOCIETY

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