Rchr
J-GLOBAL ID：201801004598851984
Update date: Oct. 23, 2024
Ichimura Koichi
イチムラ コウイチ | Ichimura Koichi
Affiliation and department：
Job title：
Specially Appointed Professor
Other affiliations (1)：
-
National Cancer Center
Research Institute
Homepage URL (1)：
https://www.ncc.go.jp/jp/ri/division/brain_tumor_translational_research/index.html
Research field (2)：
Pathobiochemistry
, Neurosurgery
Research keywords (7)：
germ cell tumor
, Molecular diagnostics
, Glioma
, Pediatric brain tumor
, Cancer Genomics
, Pediatric cancer
, Brain tumor
Research theme for competitive and other funds (19)：
- 2024 - 2027 転移増殖能を有する子宮筋腫の潜在的悪性特性と相関するゲノムエピゲノム変異の解明
- 2023 - 2026 Epigenetic regulation of inherited aortic disease
- 2022 - 2025 ロングリード技術を用いた統合ゲノム解析による中枢神経系胚細胞腫の病態解明
- 2022 - 2025 ロングリード技術を用いた統合ゲノム解析による中枢神経系胚細胞腫の病態解明
- 2021 - 2024 脳悪性リンパ腫における髄液中DNAの特異的遺伝子変異検出による診断の前方視的検討
- 2021 - 2024 Revealing specific local invasion mechanism in CNS using small cell lung cancer metastasis cell lines
- 2020 - 2024 中枢神経系悪性リンパ腫の腫瘍内多様性と微小環境解析による病態発生の解明と治療開発
- 2020 - 2023 網羅的メチル化解析で同定された頭蓋内高悪性度胚細胞腫治療標的候補分子群の機能解析
- 2020 - 2023 Comprehensive molecular and genetic analysis for prognostic and predictive factors in clinical trial for primary cnetral nervous system lymphoma
- 2019 - 2023 悪性脳腫瘍におけるポリグルタミル化制御による新規治療法の開発
- 2019 - 2022 A comprehensive genomic analysis of central nervous system germ cell tumors and generation of their cellular model
- 2018 - 2021 Comparative genetic analysis of central nervous system lymphomas between sites in the central nervous system or extracranial organs
- 2017 - 2021 Development of non-invasive novel diagnostic methods for primary central nervous system lymphoma using liquid biopsy for nucleic acids derived from cerebrospinal fluid
- 2016 - 2021 Detection and clinical application of pilocytic astrocytoma minimal residual disease
- 2016 - 2020 Functional analysis of specific genetic alterations in primary central nervous system lymphomas and development of novel molecular targeted therapies
- 2016 - 2019 Investigation of TERT expression and development of a novel targeted therapy in ependymomas
- 2016 - 2018 enome-wide DNA methylation profiling identifies primary central nervous system lymphomas as a distinct entity from systemic diffuse large B-cell lymphomas
- 2013 - 2016 Identification of novel prognostic markers for glioblastomas by means of next-generation sequencing-ased targeted resequencing
- 1991 - 1991 聴神経鞘腫および両側性神経線維腫症の遺伝子のクローニングに関する研究
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Papers (343)：
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Ryoji Imoto, Yoshihiro Otani, Kentaro Fujii, Joji Ishida, Shuichiro Hirano, Naoya Kemmotsu, Yasuki Suruga, Ryo Mizuta, Yasuhito Kegoya, Yohei Inoue, et al. Tectal glioma: clinical, radiological, and pathological features, and the importance of molecular analysis. Brain tumor pathology. 2024
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Yoshiko Nakano, Sumihito Nobusawa, Aiko Sato-Otsubo, Takuma Nakashima, Hiromichi Suzuki, Kai Yamasaki, Takahiro Shirakura, Takeshi Inoue, Takahiro Okuno, Motohiro Kato, et al. TCF3::BEND2 in paediatric supratentorial tumour with carcinoma-like epithelial features classifying as MN1-altered astroblastoma by DNA methylation profiling. Neuropathology and applied neurobiology. 2024. 50. 5. e13011
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Yuta Sekino, Yukihiko Sonoda, Ichiyo Shibahara, Junki Mizusawa, Keita Sasaki, Tetsuya Sekita, Mayumi Ichikawa, Hiroshi Igaki, Manabu Kinoshita, Toshihiro Kumabe, et al. Protocol digest of a phase III randomized trial of gross total resection versus possible resection of fluid-attenuated inversion recovery-hyperintense lesion on MRI for newly diagnosed supratentorial glioblastoma: JCOG2209 (FLAMINGO). Japanese journal of clinical oncology. 2024
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Yukihiko Sonoda, Yuta Sekino, Junki Mizusawa, Ichiyo Shibahara, Keita Sasaki, Tetsuya Sekita, Mayumi Ichikawa, Hiroshi Igaki, Manabu Kinoshita, Junji Shibahara, et al. AB012. A phase III randomized trial of gross total resection versus possible resection of fluid-attenuated inversion recovery (FLAIR) hyperintensity lesion on magnetic resonance image for newly diagnosed supratentorial glioblastoma (JCOG2209). Chinese clinical oncology. 2024. 13. Suppl 1. AB012
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Sina Neyazi, Erika Yamazawa, Karoline Hack, Shota Tanaka, Genta Nagae, Catena Kresbach, Takayoshi Umeda, Alicia Eckhardt, Kenji Tatsuno, Lara Pohl, et al. Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation. Acta Neuropathologica. 2024. 147. 1
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MISC (154)：
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駿河和城, 大谷理浩, 松本悠司, 石田穣治, 井上陽平, 平野秀一郎, 藤井謙太郎, 柳井広之, 山本英喜, 里見介史, et al. Analysis of the tumor microenvironment in NF1-related gliomas. 小児の脳神経(Web). 2024. 49. 2
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藤本健二, 北原麻衣, 服部奈緒子, 松下裕子, 松下裕子, 日比谷優子, 日比谷優子, 里見介史, 里見介史, 堤信二, et al. Long-term administration of mutant IDH inhibitor DS-1001b confers an anti-tumor effect on IDH1 mutant glioma cell lines. 日本脳腫瘍学会学術集会プログラム・抄録集. 2023. 41st
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田尾 佳代子, 加藤 元博, 義岡 孝子, 加藤 実穂, 久保 崇, 高阪 真路, 谷田部 恭, 瀧本 哲也, 市村 幸一, 望月 慎史, et al. 小児・AYAがんにおけるゲノム医療の現状と課題 全国小児がんゲノムプロファイリングプロジェクト JCCG-TOP2. 日本癌治療学会学術集会抄録集. 2022. 60回. OWS23-3
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高橋 雅道, 川嶋 聡, 口羽 文, 佐立 崚, 米盛 勧, 永根 基雄, 荒川 芳輝, 武笠 晃丈, 田中 將太, 西川 亮, et al. 再発膠芽腫に対するエリブリンの第2相多施設単群医師主導治験. 日本癌治療学会学術集会抄録集. 2022. 60回. EN6-3
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田尾 佳代子, 加藤 元博, 義岡 孝子, 加藤 実穂, 久保 崇, 高阪 真路, 谷田部 恭, 瀧本 哲也, 市村 幸一, 望月 慎史, et al. 全国小児がんゲノムプロファイリングプロジェクト JCCG-TOP2(The Nationwide Pediatric Cancer Genome Profiling Project: JCCG-TOP2). 日本癌学会総会記事. 2022. 81回. P-1071
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Education (3)：
- 1994 - 1996 Karolinska Institute Tumor Pathology
- 1992 - 1994 Gothenburg University Department of Pathology
- 1979 - 1985 Tokyo Medical and Dental University School of Medicine
Professional career (1)：
- M.D., Ph.D. (Karolinska Institute, Stockholm)
Work history (13)：
- 2024/04 - 現在 Kyorin University Department of Pathology, Faculty of Medicine Specially Appointed Professor
- 2021/04 - 2024/03 Juntendo University Department of Brain Disease Translational Research, Faculty of Medicine Specially Appointed Professor
- 2011/10 - 2021/03 National Cancer Center Japan Brain Tumor Translational Research Chief
- 1998/07 - 2011/06 University of Cambridge Department of Pathology Senior Research Associate
- 1996/07 - 1998/06 Ludwig Institute for Cancer Research Stockholm branch Postdoctoral fellow
- 1994/05 - 1996/06 Karolinska Institute Tumor Pathology Doctoral student
- 1989/10 - 1994/09 Tokyo Medical and Dental University Department of Neurosurgery Research Associate
- 1991/10 - 1994/04 University of Gothenburg Department of Pathology Doctoral student
- 1988/10 - 1989/09 Tokyo Medical and Dental University Department of Neurosurgery
- 1987/07 - 1988/09 富士吉田市立病院 脳神経外科 医員
- 1986/07 - 1987/06 Tokyo Medical and Dental University Department of Neurosurgery
- 1985/11 - 1986/06 土浦協同病院 脳神経外科 医員
- 1985/06 - 1985/10 Tokyo Medical and Dental University Department of Neurosurgery
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Association Membership(s) (7)：
AMERICAN ASSOCIATION FOR CANCER RESEARCH
, THE SOCIETY OF NEURO-ONCOLOGY
, THE JAPAN SOCIETY OF MOLECULAR NEUROSURGERY
, THE JAPAN NEUROSURGICAL SOCIETY
, THE JAPANESE CANCER ASSOCIATION
, THE JAPAN SOCIETY OF BRAIN TUMOR PATHOLOGY
, THE JAPAN SOCIETY FOR NEURO-ONCOLOGY
