Makoto Yamasaki

2016 - 2019 A comprehensive study related to the mechanism and usefulness of pre-operative intervention on physical frailty as a poor prognostic factor after surgery for gastrointestinal cancer in older adults

2016 - 2019 Development of the selective ghrelin replacement therapy according to the ghrelin dependency in each patient

2015 - 2018 The mechanisms for acquired imatinib resistance beyond secondary KIT mutations in gastrointestinal stromal tumor

2015 - 2018 Breakthrough in clinical application and optimization of ghrelin administration by clarifying the mechanism of alleviating surgical stress

2015 - 2018 Development of a ghrelin supportive therapy for patients with high invasive surgery and highly morbidity risks

2013 - 2016 The previous clinical study about feasibility and utility of Steady Pressure Automatically Controlled Endoscopy at the time of gastrointestinal perforation

2012 - 2015 The role of cancer-related exosome on chemoresistance in esophageal cancer

2011 - 2013 The exploration of novel therapeutic target in gastric cancer by comprehensive tyrosine-kinase analysis

2011 - 2013 Effect of synthesis ghrelin administration for the management of inflammation after esophagectomy

2009 - 2011 The role of bone marrow-derived cells in chemoresistance of esophageal cancer

2009 - 2010 Common経路とspecific経路による食道癌化学療法感受性の解析

2008 - 2010 Application of novel gastrointestinal hormone ghrelin for improvement of QOL after upper digestive tract surgery

2007 - 2008 construction of prediction system for theresponse to chemotherapyfor esophageal cancer using custom DNA chip

2007 - 2008 DNAマイクロアレイによる幹細胞融合による消化器発癌の可能性の検討

2007 - 2008 A novel therapeutic strategy based on tumor-specific energy metabolism