Rchr
J-GLOBAL ID:201801004740649691   Update date: Nov. 18, 2024

Tomimatsu Kosuke

Tomimatsu Kosuke
Affiliation and department:
Research field  (4): Cell biology ,  Tumor biology ,  Genetics ,  Systems genomics
Research keywords  (3): Cellular Senescence ,  Chromatin ,  Epigenetics
Research theme for competitive and other funds  (22):
  • 2024 - 2029 生体イメージングと AI 解析による早期加齢変容・進展機構の解明
  • 2024 - 2027 Mechanism of sarcomagenesis by 3-d epigenome analysis of gynecological carcinosarcoma
  • 2024 - 2027 新しい細胞外マトリックス蛋白SVEP1の心不全病態形成における役割・意義の解明
  • 2023 - 2026 空間マルチオミクス解析による急性冠症候群の発症機序解明
  • 2023 - 2026 子宮体癌とその前癌病変である内膜増殖症の空間的エピゲノム解析
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Papers (31):
  • Yasuyuki Ohkawa, Akihito Harada, Takeru Fujii, Kosuke Tomimatsu, Michiko Kato, Miho Ito, Kazumitsu Maehara, Shoko Sato, Hitoshi Kurumizaka, Yuko Sato, et al. Tracking chromatin structure changes by single-cell multi-epigenomics with RNA polymerase II binding profiles. ResearchSquare. 2024
  • Precise immunofluorescence canceling for highly multiplexed imaging to capture specific cell states. Nature Communications. 2024. 15. 3657
  • Kosuke Tomimatsu, Takeru Fujii, Ryoma Bise, Kazufumi Hosoda, Yosuke Taniguchi, Hiroshi Ochiai, Hiroaki Ohishi, Kanta Ando, Ryoma Minami, Kaori Tanaka, et al. Precise immunofluorescence canceling for highly multiplexed imaging capturing specific cell state. bioRxiv. 2023
  • Sushil Bhandari, KwangHeum Hong, Atsuko Miyawaki-Kuwakado, Kosuke Tomimatsu, Yong-Il Kim, In-Koo Nam, Charles G Sagerstrom, Mako Nakamura, Seong-Kyu Choe. nudt7 gene depletion causes transcriptomic change in early development of zebrafish. Journal of biochemistry. 2022
  • Kosuke Tomimatsu, Dóra Bihary, Ioana Olan, Aled J. Parry, Stefan Schoenfelder, Adelyne S. L. Chan, Guy St. C. Slater, Yoko Ito, Peter J. Rugg-Gunn, Kristina Kirschner, et al. Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. Nature Aging. 2022
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Books (7):
  • 生化学96巻3号 ことばのページ 転写ハブ
    日本生化学会 2024
  • 月刊 Precision Medicine 病理/組織画像評価法の潮流
    北隆館 2023
  • 生体の科学[特集]クロマチンによる転写制御機構の最前線
    公益財団法人金原一郎記念医学医療振興財団/医学書院 2023
  • エピゲノムで新たな解明が進む「先天性疾患」
    株式会社 メディカルドゥ 2021
  • ダイレクトリプログラミング 再生医療の新展開
    (株)エヌ・ティー・エス 2020
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Lectures and oral presentations  (21):
  • 1細胞空間オミクス技術開発で細胞状態変化を高解像に捉える
    (国立循環器病研究センターセミナー 2024)
  • Highly multiplexed imaging to analyze senescence dynamics
    (JP-UK Joint Symposium for Senescence Research 2024)
  • Precise immunofluorescence canceling for highly multiplexed imaging reveals specific cell states
    (2024)
  • Precise immunofluorescence canceling enables highly multiplexed imaging to analyze senescence dynamics
    (FASEB Science Research conferences, Transcription, Chromatin, and Epigenetics in Aging, Melbourne Florida, USA 2024)
  • Development of spatial multi-omics methods to measure cell states in cancer tissues
    (2024)
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Work history (10):
  • 2021/10 - 現在 Medical Institute of Bioregulation, Kyushu University Assistant Professor
  • 2020/04 - 2021/09 Kyushu University Medical Institute of Bioregulation
  • 2018/03 - 2020/03 Shiga University of Medical Science
  • 2015/04 - 2018/03 Cancer Research UK, Cambridge Institute, University of Cambridge Research Associate
  • 2013/03 - 2015/03 Cancer Research UK, Cambridge Institute, University of Cambridge Visiting Scientist
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Association Membership(s) (1):
日本エピジェネティクス研究会
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