TORITSUKA Michihiro

トリツカミチヒロ | TORITSUKA Michihiro

Affiliation and department：
Other affiliations (1)：

Nara Medical University Department of Psychiatry

Research field (1)： Psychiatry

Research theme for competitive and other funds (9)：

2022 - 2025 免疫系細胞とヒトiPSニューロン共培養系によるASDの病態解析
2021 - 2023 自閉スペクトラム症におけるM2マクロファージ機能不全に着目した病態解明
2020 - 2023 小児期栄養環境が形づくる髄鞘構造とその精神症状への効果の検討
2019 - 2022 Pathophysiological analysis of schizophrenia and ASD by using the co-culture system of macrophages and hiPSC-derived neurons.
2018 - 2022 Identification of the psychobiotics in young patients with anorexia nervosa by multidimensional analysis: Toward the discovery of therapeutic agents

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Papers (55)：

Yasunari Yamaguchi, Kazuya Okamura, Kazuhiko Yamamuro, Kazuki Okumura, Takashi Komori, Michihiro Toritsuka, Ryohei Takada, Yosuke Nishihata, Daisuke Ikawa, Takahira Yamauchi, et al. NARP-related alterations in the excitatory and inhibitory circuitry of socially isolated mice: developmental insights and implications for autism spectrum disorder. Frontiers in Psychiatry. 2024. 15
Ryohei Takada, Michihiro Toritsuka, Takahira Yamauchi, Rio Ishida, Yoshinori Kayashima, Yuki Nishi, Mitsuru Ishikawa, Kazuhiko Yamamuro, Minobu Ikehara, Takashi Komori, et al. Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines. Molecular autism. 2024. 15. 1. 10-10
Takashi Komori, Kazuya Okamura, Minobu Ikehara, Kazuhiko Yamamuro, Nozomi Endo, Kazuki Okumura, Takahira Yamauchi, Daisuke Ikawa, Noriko Ouji-Sageshima, Michihiro Toritsuka, et al. Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior. Molecular psychiatry. 2024
Yasunari Yamaguchi, Kazuya Okamura, Kazuhiko Yamamuro, Kazuki Okumura, Takashi Komori, Michihiro Toritsuka, Ryohei Takada, Yosuke Nishihata, Daisuke Ikawa, Takahira Yamauchi, et al. NARP-related alterations in the excitatory and inhibitory circuitry of socially isolated mice: developmental insights and implications for autism spectrum disorder. Frontiers in psychiatry. 2024. 15. 1403476-1403476
Noriyoshi Usui, Miyuki Doi, Stefano Berto, Kiwamu Matsuoka, Rio Ishida, Koichiro Irie, Nanako Nakama, Hana Miyauchi, Yuuki Fujiwara, Takahira Yamauchi, et al. Copper-deficiency is associated with impairments in social behavior and oligodendrocyte development via mTOR signaling pathway. 2023

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MISC (66)：

西佑記, 高田涼平, 鳥塚通弘, 石田理緒, 萱島善徳, 神川浩平, 竹田奨, 石川充, 山内崇平, 岡野栄之, et al. Evaluation of phagocytosis in macrophages from patients with autism spectrum disorder. 日本生物学的精神医学会(Web). 2023. 45th
小森崇史, 池原実伸, 盛本翼, 本多将人, 南明宏, 生野兼広, 山室和彦, 鳥塚通弘, 牧之段学. 高度救命救急センターから転棟となる自殺企図事例の動向と自殺再企図予防への取り組み. 日本精神科救急学会学術総会プログラム・抄録集. 2023. 31st
高田涼平, 鳥塚通弘, 山内崇平, 萱島善徳, 石田理緒, 西佑記, 石川充, 岡野栄之, 牧之段学. Pathophysiological analysis of autism spectrum disorder using the co-culture system of human iPS cell-derived neurons and macrophages. 日本生物学的精神医学会(Web). 2022. 44th
小森崇史, 岡村和哉, 池原実伸, 井川大輔, 山室和彦, 山内崇平, 鳥塚通弘, 高田涼平, 森祐貴, 萱島善徳, et al. マイクログリア由来BDNFの過剰発現は発達期の社会脳形成を妨げる. 日本神経化学会大会抄録集(Web). 2022. 65th
山内崇平, 萱嶋善徳, 今井一彰, 神川浩平, 高田涼平, 小森崇史, 石田理緒, 岸本直子, 鳥塚通弘, 牧之段学. ASD血漿中のTNF-α発現とASD諸症状との相関解析. 日本神経化学会大会抄録集(Web). 2022. 65th

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