Research field (2):
Biomaterials
, Biomedical engineering
Research theme for competitive and other funds (14):
2022 - 2024 A patterned scaffold that can form pancreatic islet-like tissues for diabetes treatment
2021 - 2024 Preparation of novel photodynamic therapy using locally injected tissue-adhesive porphyrins
2021 - 2024 Composite scaffolds for programmed control of stem cell proliferation and differentiation
2019 - 2022 Development of multifunctional hybrid porous scaffolds for cancer therapy and tissue engineering
2018 - 2020 Development of a three dimensional scaffold with micropatterned structure for vascularized large bone regeneration
2018 - 2020 大きな骨再生と血管新生を促進する三次元マイクロパターン化足場材料の創出
2015 - 2018 Development of Matrix Materials Mimicking Simultaneous Osteogenesis and Adipogenesis
2014 - 2017 Elucidation of the oral biofilm prevention mechanism by photocatalytic devices and their practical application
2013 - 2015 Development of porous scaffolds with micropatterned bioactive molecules
2012 - 2015 Development of autologous scaffolds
2001 - 2002 光捕集機能性ペプチド骨格デンドリマーの合成と機能解析
1999 - 2001 Construction of cell culture system by combining cell design using transfection of genes and material design using immobilization of biological molecules
1999 - 2000 物質輸送を精密に制御できる高分子ブラシ自己集積化多孔性膜の設計と合成
1999 - 1999 糖鎖の密度傾斜固定化による細胞機能制御
Show all
Papers (224):
Rui Sun, Man Wang, Tianjiao Zeng, Huajian Chen, Toru Yoshitomi, Masaki Takeguchi, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Scaffolds functionalized with matrix metalloproteinase-responsive release of miRNA for synergistic magnetic hyperthermia and sensitizing chemotherapy of drug-tolerant breast cancer. Bioactive Materials. 2025. 44. 205-219
Rui Sun, Huajian Chen, Man Wang, Toru Yoshitomi, Masaki Takeguchi, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Smart composite scaffold to synchronize magnetic hyperthermia and chemotherapy for efficient breast cancer therapy. Biomaterials. 2024. 307. 122511-122511
Tianjiao Zeng, Huajian Chen, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Effect of Hydrogel Stiffness on Chemoresistance of Breast Cancer Cells in 3D Culture. Gels (Basel, Switzerland). 2024. 10. 3
Saori Fujiwara, Toru Yoshitomi, Aoi Hoshi, Van Thi Hong Doan, Yoshiki Komatsu, Huajian Chen, Naoki Kawazoe, Guoping Chen, Azusa Terasaki, Hiroko Bando, et al. Locally Administered Photothermal Therapy for Breast Cancer using Endolysosome-Targeted Indocyanine Green Conjugated with Polycation. Journal of Surgery and Research. 2024. 07. 01. 122-133
2018/09 - Romanian Society for Biomaterials SRB Excellence Award Cellular nanomechanics of stem cells and cancer cells confined to micropatterned surfaces
2014/09 - Organizing Committee of TERMIS-AP 2014 SYIS Oral Presentation Award Stemness variation of human mesenchymal stem cells on micropatterned structures
2008/11 - The Asian-Pacific Chapter of Tissue Engineering & Regenerative Medicine International Society Best Travel Award Adipogenic Differentiation of Mesenchymal stem cells on Micropatterned Polymer Surfaces
Association Membership(s) (3):
THE SOCIETY OF POLYMER SCIENCE, JAPAN
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
, THE JAPANESE SOCIETY FOR BIOMATERIALS