1998 - 2000 Development of a novel controller for antimicrobial nisin production, using interaction of microorganisms
1998 - 2000 Isolation of a novel bacteriocin-producing lactic acid bacteria and its use in food preservation
1996 - 1998 Development of an on-line fault diagnosis and operation system for an optimal rice-alphaamylase production process of temperature-sensitive mutant of Saccharomyces cerevisiae by autoassociative neural network
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Papers (40):
Hideyuki Hara, Junji Chida, Keiji Uchiyama, Agriani Dini Pasiana, Etsuhisa Takahashi, Hiroshi Kido, Suehiro Sakaguchi. Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells. Scientific Reports. 2021. 11. 1
Ethanolamine Is a New Anti-Prion Compound. International Journal of Molecular Sciences. 2021. 22. 11742
Hideyuki Hara, Junji Chida, Agriani Dini Pasiana, Keiji Uchiyama, Yutaka Kikuchi, Tomoko Naito, Yuichi Takahashi, Junji Yamamura, Hisashi Kuromatsu, Suehiro Sakaguchi. Vaporized Hydrogen Peroxide and Ozone Gas Synergistically Reduce Prion Infectivity on Stainless Steel Wire. International Journal of Molecular Sciences. 2021. 22. 6. 3268-3268
Keiji Uchiyama, Hironori Miyata, Yoshitaka Yamaguchi, Morikazu Imamura, Mariya Okazaki, Agriani Dini Pasiana, Junji Chida, Hideyuki Hara, Ryuichiro Atarashi, Hitomi Watanabe, et al. Strain-Dependent Prion Infection in Mice Expressing Prion Protein with Deletion of Central Residues 91-106. International journal of molecular sciences. 2020. 21. 19
Junji Chida, Hideyuki Hara, Keiji Uchiyama, Etsuhisa Takahashi, Hironori Miyata, Hidetaka Kosako, Yukiko Tomioka, Toshihiro Ito, Hiroyuki Horiuchi, Haruo Matsuda, et al. Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice. PLoS pathogens. 2020. 16. 8. e1008823
Prions: Current Progress in Advanced Research (Second Edition)
Caister Academic Press 2019
Prions - Some Physiological and Pathophysiological Aspects
IntechOpen 2018
Prions: Current progress in advanced research
Caister Academic Press 2013
生物工学実験書
The Society for Biotechnology, Japan 2002
Microbiology of Composting
Springer-Verlag 2002
Lectures and oral presentations (55):
Analysis of intracellular secretion processes by Citrine fusion IgG aiming to establish high producer CHO cells.
(The 31st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2018 Tsukuba) 2018)
High susceptibility of Sortilin-deficient cells to prion infection.
(第65回日本ウイルス学会学術集会 2017)
Identification and investigation of a novel anti-prion compound.
(第65回日本ウイルス学会学術集会 2017)
高生産株の構築を目指した抗体生産CHO細胞内の分泌過程解
(第69回日本生物工学会大会 2017)
Prion propagation through sortilin degradation.
(第60回日本神経化学会大会 2017)
2003/10 - 2004/03 University of Cambridge Cambridge Institute for Medical Research Senior Research Associate
2000/03/18 - 2003/10/15 University of Cambridge Cambridge Institute for Medical Research Visiting Resercher
1997/04/01 - 2003/10/15 Osaka University Graduate School of Engineering
2000/03 - 2003/10 University of Cambridge Cambridge Institute for Medical Research Visiting Researcher
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Awards (3):
2016/11/12 - The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology Best Oral Presentation Awards Analysis of intracellular recombinant IgG secretion in engineered CHO cells
2015/09/05 - Asia Pacific Society of Prion Research (APSPR) Asia Pacific Prion Symposium 2015, The Best Poster Award Mechanism of Sortilin-Mediated PrP degradation
2014/01/28 - The Koraku Foundation 康楽賞 プリオン病における神経細胞死誘導機構の解明と治療への応用
Association Membership(s) (7):
日本癌学会
, 日本がん分子標的治療学会
, The Japanese Society for Virology
, Asian Pacific Society of Prion Research (APSPR)
, The Japanese Biochemical Society
, Japan Society for Cell Biology
, The Molecular Biology Society of Japan