Misa Oyama

オヤマミサ | Misa Oyama

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： http://www.pharm.kitasato-u.ac.jp/pharmacology/

Research field (2)： Pharmacology , Neuroscience - general

Research keywords (1)： electrophysiology, behavioral study, pain, itch

Research theme for competitive and other funds (3)：

2023 - 2025 The analysis of the analgesic effects of novel glycine receptor positive allosteric modulators (PAMs) and their synaptic mechanisms
2022 - 2025 Pharmacological analysis of antipruritic effects of gabapentinoid
2019 - 2022 The synaptic analgesic mechanisms of KCNQ (Kv7) K+ channel opener in the spinal dorsal horn.

Papers (7)：

Takashi Iwai, Rei Mishima, Shigeto Hirayama, Honoka Nakajima, Misa Oyama, Shun Watanabe, Hideaki Fujii, Mitsuo Tanabe. SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted Neurogenesis. Journal of Clinical Medicine. 2024. 13. 2. 608-608
Motoki Morita, Shun Watanabe, Natsumi Nomura, Kanako Takano-Matsuzaki, Misa Oyama, Takashi Iwai, Mitsuo Tanabe. Sulfatide-selectin signaling in the spinal cord induces mechanical allodynia. Journal of neurochemistry. 2022
Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Distinct synaptic mechanisms underlying the analgesic effects of γ-aminobutyric acid transporter subtypes 1 and 3 inhibitors in the spinal dorsal horn. Pain. 2022. 163. 2. 334-349
Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Mirogabalin activates the descending noradrenergic system by binding to the α2δ-1 subunit of voltage-gated Ca2+ channels to generate analgesic effects. Journal of pharmacological sciences. 2021. 146. 1. 33-39
Takashi Iwai, Akinori Kikuchi, Misa Oyama, Shun Watanabe, Mitsuo Tanabe. Mirogabalin prevents repeated restraint stress-induced dysfunction in mice. Behavioural brain research. 2020. 383. 112506-112506

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MISC (2)：

Misa Oyama. マークミスから始まった薬理学研究. 2020. 155. 3. 196-196
宿利美香, 大内彩子, 内藤康仁, 岩井孝志, 渡辺俊, 尾山実砂, 植松智, 審良静男, Jakobsson Per-Johan, 田辺光男, et al. mPGES-1阻害薬のマウス脳梗塞障害改善機序. 日本薬学会年会要旨集. 2018. 138年会. 3. 95-95

Lectures and oral presentations (82)：

Effects of KNT-127, a delta opioid receptor agonist, on non-REM sleep in mice.
(2022)
Mirogabalin and pregabalin, α2δ subunit ligands of voltage-gated Ca2+ channels, suppress acute and chronic itch.
(2022)
The involvements of sulfatide-selectin signaling in the spinal cord on inflammatory pain
(2022)
δオピオイド受容体作動薬KNT-127の睡眠に対する影響
(BPCNPNPPP4学会合同年会(第44回日本生物学的精神医学会年会/第32回日本臨床精神神経薬理学会年会/第52回日本神経精神薬理学会年会/第6回日本精神薬学会総会・学術集会) 2022)
皮膚炎におけるシアル酸分解酵素による鎮痛作用と表皮内神経線維への影響
(第41回糖質学会年会 2022)

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Education (2)：

2015 - 2017 Kitasato Univ. School of Pharmaceutical Sciences
2009 - 2015 Kitasato Univ. School of Pharmacy Pharmaceutical Scieces

Work history (2)：

2023/04 - 現在 University of Zurich Institute of Pharmacology and Toxicology Postdoctoral fellow
2017/04 - 現在 School pf Pharmacy, Kitasato University Laboratory of Pharmacology Assistant Professor

Awards (1)：

2022/03 - Young Investigator's Award (YIA) Behavioral and electrophysiological analysis of the analgesic and antipruritic effects of the KCNQ (Kv7) K+ channel opener retigabine.

Association Membership(s) (4)：

JAPANESE ASSOCIATION FOR THE STUDY OF PAIN , THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE PHARMACOLOGICAL SOCIETY , THE PHARMACEUTICAL SOCIETY OF JAPAN

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