Yukawa Masashi

ユカワマサシ | Yukawa Masashi

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Applied biochemistry

Research theme for competitive and other funds (8)：

2023 - 2025 酵母を利用した抗がん活性を有する天然物由来新規キネシン阻害剤の探索
2019 - 2022 Elucidation of molecular mechanisms regulating bipolar spindle assembly and its application for next-generation drug discovery
2016 - 2021 Exploring spatiotemporal regulatory mechanisms of proper mitotic spindle assembly mediated by novel evolutionarily conserved pathways
2016 - 2019 Single-molecule visualisation of kinetochore-microtubule interface using the in vitro reconstitution system
2016 - 2018 Molecular mechanisms of bipolar spindle assembly in the absence of Kinesin-5/Cut7

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Papers (40)：

Toda, Takashi, Kitamura, Kenji, Kume, Kazunori, Yukawa, Masashi, Koyano, Takayuki, Ueno, Masaru. The joy of the 11th International Fission Yeast Meeting in Hiroshima (POMBE2023 Hiroshima) after a long wait due to the COVID-19 pandemic. GENES TO CELLS. 2023. 28. 9. 646-652
Woosang Hwang, Takashi Toda and Masashi Yukawa. Complementation of fission yeast kinesin-5/Cut7 with human Eg5 provides a versatile platform for screening of anticancer compounds. Bioscience, Biotechnology, and Biochemistry. 2022. 86. 2. 254-259
Masashi Yukawa, Mitsuki Ohishi, Yusuke Yamada and Takashi Toda. The putative RNA-binding protein Dri1 promotes the loading of kinesin-14/Klp2 to the mitotic spindle and is sequestered into heat-induced protein aggregates in fission yeast. International Journal of Molecular Sciences. 2021. 22. 9. 4795
Shintaro Akabane 1 2 , Naohide Oue 1 , Yohei Sekino 3 , Ryuichi Asai 4 , Pham Quoc Thang 1 , Daiki Taniyama 1 , Kazuhiro Sentani 1 , Masashi Yukawa 5 , Takashi Toda 5 , Ken-Ichi Kimura 6 , Hiroyuki Egi 2 , Wataru Shimizu 2 , Hideki Ohdan 2 , Wataru Yasui 1. KIFC1 regulates ZWINT to promote tumor progression and spheroid formation in colorectal cancer. Pathology International. 2021. 71. 7. 441-452
Masashi Yukawa, Yasuhiro Teratani and Takashi Toda. Escape from mitotic catastrophe by actin-dependent nuclear displacement in fission yeast. iScience. 2021. 24. 1. 102031

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Books (7)：

A novel pathway involved in mitotic nuclear positioning in fission yeast
Journal of Japanese Biochemical Society 2023
もう一つの広島サミット〜第11回分裂酵母国際学会
羊土社 2023 ISBN:9784758125710
熱ショックシャペロンによるMAPキナーゼ経路の二面的制御
羊土社 2021 ISBN:9784758125413
タンパク質脱リン酸化酵素の“えこ贔屓”:2A型フォスファターゼPP2A-B55はセリンよりスレオニンがお好き
2018 ISBN:9784758125048
今日の話題ヒストン脱アセチル化酵素を介した転写タイミングの調節--細胞増殖・発生・分化の過程での遺伝子発現制御の一端が明らかに
2007

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Lectures and oral presentations (74)：

分裂酵母の生育に必須な微小管結合因子Peg1/CLASP の紡錘体形成における役割
(日本農芸化学会2024年度大会 2024)
アクチン繊維による分裂期特異的細胞核移動の分子制御機構
(第40回イーストワークショップ 2023)
A fission yeast-based platform for screening potent human kinesin-5/Eg5 inhibitors
(2023)
Exploring the molecular mechanism of actin-dependent mitotic nuclear positioning
(The 2023 Cold Spring Harbor Asia conference on Yeast and Life Sciences 2023)
アクチン繊維による核移動を介した細胞分裂死回避機構
(第23回真核微生物交流会 2023)

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Association Membership(s) (3)：

Yeast Genetics Society of Japan , The Molecular Biology Society of Japan (MBSJ) , Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA)

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