Rchr
J-GLOBAL ID：201801005132960410   Update date: Oct. 22, 2024

Kihara Takanori

キハラ タカノリ | Kihara Takanori
Affiliation and department：
The University of Kitakyushu Faculty of Environmental Engineering

About The University of Kitakyushu Faculty of Environmental Engineering


Homepage URL  (1)： https://takanori-kihara.jimdo.com/
Research field  (3)： Cell biology ,  Biomaterials ,  Biomedical engineering
Research keywords  (10)： コラーゲン ,  細胞接着 ,  Mesenchymal stem cell ,  Extracellular matrix ,  Nano Biotechnology ,  Deep Learning ,  Cell engineering ,  Atomic Force Microscopy ,  Smooth muscle cell ,  Biomineralization
Research theme for competitive and other funds  (11)：
  • 2024 - 2027 エクソソームによる骨組織形成制御と骨組織によるエクソソーム貯蔵
  • 2021 - 2024 ヒト筋線維芽細胞の平滑筋細胞形質転換にかかる分子機構の解析と形質転換要素の同定
  • 2016 - 2019 エクソソームを基軸とした石灰化形成機構の解明
  • 2015 - 2016 石灰化に対する各種細胞外基質分子の効果
  • 2011 - 2016 Development of a nanoprobe for measuring the molecular dynamics in living cells
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Papers (42)：
  • Do, T.L, Tachibana, K, Yamamoto, N, Ando, K, Isoda, T, Kihara, T. Interaction of SARS-CoV-2 Spike protein with ACE2 induces cortical actin modulation, including dephosphorylation of ERM proteins and reduction of cortical stiffness. 2025. 38. 3
  • Tachibana, K, Nakamura, Y, Do, T.L, Kihara, T, Kawada, H, Yamamoto, N, Ando, K. Mutations in the SARS-CoV-2 Spike proteins affected the ACE2-binding affinity during the development of Omicron pandemic variants. Biochem Biophys Res Commun. 2024. 719. 150120
  • Phan, T.K.T, Do, T.L, Tachibana, K, Kihara, T. Alpha-mangostin dephosphorylates ERM to induce adhesion and decrease surface stiffness in KG-1 cells. Human Cell. 2022. 35. 1. 189-198
  • Kihara, T, Matsumoto, T, Nakahashi, Y, Tachibana, K. Mechanical stiffness softening and cell adhesion are coordinately regulated by ERM dephosphorylation in KG-1 cells. 2021. 34. 6. 1709-1716
  • Thi Kieu Trang Phan, Fahimeh Shahbazzadeh, Takanori Kihara. Alpha-mangostin reduces mechanical stiffness of various cells. Human Cell. 2020. 33. 2. 347-355
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MISC (16)：
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Education (3)：
  • 2004 - 2006 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
  • 2000 - 2002 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
  • 1996 - 2000 The University of Tokyo College of Arts and Sciences Department of Life and Cognitive Sciences
Professional career (1)：
  • 博士(学術) (東京大学)
Work history (6)：
  • 2024/04 - 現在 The University of Kitakyushu Faculty of Environmental Engineering Professor
  • 2013/04 - 2024/03 The University of Kitakyushu Faculty of Environmental Engineering
  • 2009/09 - 2013/03 Osaka University Graduate School of Engineering Science
  • 2006/04 - 2009/08 The University of Tokyo The Graduate School of Engineering
  • 2005/04 - 2006/03 The University of Tokyo Graduate School of Arts and Sciences
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Awards (5)：
  • 2017 - 2017 Kyushu-Seibu/Pusan-Gyeongnam Joint Symposium on High Polymer (18th) and Fibers (16th) Poster Presentation Award Alpha-mangostin inhibits migration and invasion of cancer cells
  • 2016 - Interdisciplinary Medial, Dental and Soft-material Researches on the move -Showcase Review in Kitakyushu- Award for Best Poster Presentation How do osteogenic cells form calcified matrix?
  • 2015 - リバネス 第26回リバネス研究費富士フイルム賞 石灰化に対する各種細胞外基質分子の効果
  • 2012 - 22nd Anniversary World Congress on Biosensors Best Paper Award 2012 Winner Evaluation of the actin cytoskeleton state using an antibody-functionalized nanoneedle and AFM
  • 2008 - NanoBio Seoul 2008 Best Poster Award of NanoBio-Seoul 2008 Development of in situ molecular sensor by using nanoneedle technology
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