Research theme for competitive and other funds (4)：
2022 - 2025 Study of intestinal dysbiosis in patients with Fontan Circulation
2022 - 2024 代謝物が繋ぐ肺・腸・肝連関に着目した肺高血圧症の新規病態形成機構の解明
2021 - 2024 Pulmonary artery ablation for medication refractory pulmonary hypertension (PARPH) study
2020 - 2022 Exploring the new mechanisms of pulmonary hypertension with Liver RNA sequencing
Papers (25)：
Tatsuya Nishii, Hiroki Horinouchi, Takara Namboku, Keitaro Sofue, Ryotaro Asano, Akiyuki Kotoku, Yasutoshi Ohta, Takeshi Ogo, Tetsuya Fukuda. Laterality of CT-measured hepatic extracellular volume fraction in patients with chronic thromboembolic pulmonary hypertension. The international journal of cardiovascular imaging. 2024
Yoshiki Yanagi, Masashi Amano, Yurie Tamai, Ayaka Mizumoto, Shoko Nakagawa, Kenji Moriuchi, Ryotaro Asano, Shinichi Kurashima, Yuki Irie, Takahiro Sakamoto, et al. Accuracy of Shunt Volume Measured by Three-Dimensional Echocardiography and Cardiac Magnetic Resonance in Patients with an Atrial Septal Defect and a Dilated Right Ventricle. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2024
Tomohiko Ishibashi, Tadakatsu Inagaki, Makoto Okazawa, Akiko Yamagishi, Keiko Ohta-Ogo, Ryotaro Asano, Takeshi Masaki, Yui Kotani, Xin Ding, Tomomi Chikaishi-Kirino, et al. IL-6/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 16. e2315123121
Yusuke Manabe, Tomohiko Ishibashi, Ryotaro Asano, Shuichi Tonomura, Yuichi Maeda, Daisuke Motooka, Jin Ueda, Masahiro Yanagawa, Yuko Edamoto-Taira, Tomomi Chikaishi-Kirino, et al. Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis. Arthritis Research and Therapy. 2023. 25. 1
Ai Yaku, Tadakatsu Inagaki, Ryotaro Asano, Makoto Okazawa, Hiroyoshi Mori, Ayuko Sato, Fabian Hia, Takeshi Masaki, Yusuke Manabe, Tomohiko Ishibashi, et al. Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages. Circulation. 2022. 101161CIRCULATIONAHA122059435
