Rchr
J-GLOBAL ID：201801005485633502
Update date: Jun. 14, 2024
Hirose Koichi
Hirose Koichi
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Affiliation and department：
International University of Health and Welfare School of Medicine
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Detailed information
Other affiliations (2)：
千葉大学
医学部
アレルギー・臨床免疫学
特任教授
Research field (1)：
Allergies and connective tissue disease
Research theme for competitive and other funds (21)：
2021 - 2024 肺樹状細胞サブセットの同定とアレルギー性気道炎症における役割の解明
2021 - 2024 気道上皮細胞恒常性維持機構による気管支喘息抑制機構の解明
2017 - 2020 The role of IL-33-ILCs axis in the development of autoimmune arthritis
2017 - 2020 Role of epithelial glycosylation in the development of allergic airway inflammation
2016 - 2019 The regulation of IkBNS in goblet cell differentiation in asthma
2016 - 2018 Induction of class-switching from IgE to IgA as a novel treatment for allergic diseases
2015 - 2018 Analyses of epithelial-immune barrier functions in the pathogenesis of asthma
2014 - 2017 The role of Foxp3+ CD3- innate cells in allergic airway inflammation
2014 - 2017 Roles of BCL-3 in the development of TFH cells and the pathogenesis of rheumatoid arthritis
2014 - 2017 Roles of C-type lectins in the development of allergic airway inflammation
2013 - 2016 Elucidation of mechanisms underlying IL-23 production from dendritic cells in refractory asthma
2012 - 2015 Roles of epithelial cells and dendritic cells in Th17 cell-mediated airway inflammation
2011 - 2013 Roles of Th9 cells in the development of allergic glanulomatous angitis and asthma
2010 - 2011 IL-21産生制御機構と自己免疫病態におけるIL-21産生細胞の役割の解明
2009 - 2011 Investigation of mechanisms by which BTLA inhibit autoimmunity and development of potential therapeutic applications
2009 - 2011 Analysis of helper T cell subset in severe asthma for the development of new immunotherapy
2008 - 2010 The roles of Dectin-1 in the development of severe asthma
2007 - 2008 Investigation of mechanisms by which BTLA inhibit autoimmunity and its application for the treatment of autoimmune diseases
2006 - 2007 Role of IL-23/Th17 axis in allergic airway inflammation
2006 - 2007 Comprehensive Analysis of Stat5a Target Genes in Th2 Cell Differentiation
2005 - 2006 The role of B and T Lymphocyte Attenuator (BTLA) in the pathogenesis of autoimmune diseases
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Papers (133)：
Tomoaki Ida, Shunsuke Furuta, Michio Fujiwara, Masaki Hiraguri, Koichi Hirose, Kei Ikeda, Taro Iwamoto, Shin-Ichiro Kagami, Yoshihisa Kobayashi, Kazuhiro Kurasawa, et al. Short-term and long-term outcomes of patients with anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis. Rheumatology (Oxford, England). 2024
Kensuke Suga, Akira Suto, Shigeru Tanaka, Yutaka Sugawara, Takahiro Kageyama, Junichi Ishikawa, Yoshie Sanayama, Kei Ikeda, Shunsuke Furuta, Shin-Ichiro Kagami, et al. TAp63, a methotrexate target in CD4+ T cells, suppresses Foxp3 expression and exacerbates autoimmune arthritis. JCI Insight. 2023. 8. 10
井田 友明, 古田 俊介, 岩本 太郎, 池田 啓, 鈴木 浩太郎, 海辺 剛志, 大矢 佳寛, 小林 芳久, 玉地 智宏, 中込 大樹, et al. 多発性筋炎・皮膚筋炎1:抗MDA5抗体陽性症例のアウトカム 抗MDA5抗体陽性皮膚筋炎患者の長期予後に関する検討. 日本リウマチ学会総会・学術集会プログラム・抄録集. 2023. 67回. 536-536
Norihiro Mimura, Taro Iwamoto, Shunsuke Furuta, Kei Ikeda, Yoshihisa Kobayashi, Takayuki Nakamura, Aiko Saku, Shin-Ichiro Kagami, Ayako Matsuki, Kentaro Takahashi, et al. Prevalence and risk factors of osteonecrosis of the femoral head in patients with ANCA-associated vasculitis: a multicentre cohort study. RMD open. 2023. 9. 1
Yusuke Yokoyama, Tomohiro Tamachi, Arifumi Iwata, Yuko Maezawa, Kazuyuki Meguro, Masaya Yokota, Hiroaki Takatori, Akira Suto, Kotaro Suzuki, Koichi Hirose, et al. A20 (Tnfaip3) expressed in CD4+ T cells suppresses Th2 cell-mediated allergic airway inflammation in mice. Biochemical and Biophysical Research Communications. 2022
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MISC (57)：
Roles of C-type lectin receptors in allergic airway inflammation. 2020. 73. 2. 168-174
伊藤崇, 廣瀬 晃一. IL-22によるアレルギー性気道炎症制御機構. 医学のあゆみ. 2019. 268. 3. 213-214
河野 健太, 廣瀬 晃一, 牧田 荘平, 影山 貴弘, 玉地 智宏, 須藤 明, 中島 裕史. 食物アレルギーにおけるIL-21の役割の検討. アレルギー. 2018. 67. 4-5. 573-573
TANAKA Shigeru, SUTO Akira, KAGEYAMA Takahiro, TAMACHI Tomohiro, SUZUKI Kotaro, HIROSE Koichi, NAKAJIMA Hiroshi. TCR-mediated Sox12 induction promotes peripherally induced Treg cell differentiation under inflammatory conditions. 日本免疫学会総会・学術集会記録(CD-ROM). 2018. 47
上原悠治, 玉地智宏, 策愛子, 影山貴弘, 岩田有史, 鈴木浩太郎, 廣瀬晃一, 中島裕史. コーヒー(green coffee bean(GCB))焙煎による1型アレルギーの1例. アレルギー. 2018. 67. 4/5
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Lectures and oral presentations (8)：
気道上皮フコシル化はチリダニ誘導性アレルギー性気道炎症を増悪させる
(第83回日本インターフェロン・サイトカイン学会学術集会 2018)
IL-22によるアレルギー性気道炎症抑制機構
(第67回日本アレルギー学会学術大会 2018)
コーヒー(green coffee bean GCB))焙煎によるI型アレルギーの1例
(第67回日本アレルギー学会学術大会 2018)
Fut2は気道上皮フコシル化を誘導しアレルギー性気道炎症を増悪させる
(第67会日本アレルギー学会学術大会 2018)
食物アレルギーにおけるIL-21の役割の検討
(第67会日本アレルギー学会学術大会 2018)
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Work history (4)：
2017/04 - 現在 International University of Health and Welfare School of Medicine
2012/04 - 2017/04 千葉大学学院医学研究院 アレルギー・臨床免疫学 准教授
2011/04 - 2012/03 Chiba University Hospital
2005/04 - 2011/03 Chiba University Hospital
Committee career (3)：
2016/12 - 現在 日本免疫学会 評議員
2015/06 - 現在 日本アレルギー学会 代議員
2008/08 - 2010/07 文部科学省 学術調査官
Awards (1)：
2002 - 日本血液学会 奨励賞
Association Membership(s) (4)：
THE JAPANESE SOCIETY FOR IMMUNOLOGY
, JAPAN COLLEGE OF RHEUMATOLOGY
, JAPANESE SOCIETY OF ALLERGOLOGY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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