Rchr
J-GLOBAL ID:201801005646289700
Update date: Feb. 19, 2024
Hitoshi Watanabe
Hitoshi Watanabe
Affiliation and department:
Job title:
Associate Research Scientist
Research field (4):
Metabolism and endocrinology
, Food sciences
, Animal production science
, Zoological sciences
Research keywords (4):
生理学
, 栄養学
, 代謝学
, 肥満
Research theme for competitive and other funds (5):
- 2019 - 2020 GKRPアセチル化制御による肝糖取り込みメカニズムの解明
- 2016 - 2019 末梢性・中枢性セロトニンの糖脂質代謝調節作用とその有用性の解明
- 2016 - 2019 食事中タンパク質のNAFLD予防・治療作用とそのメカニズムの解明
- 2014 - 2016 ストレス応答性転写因子ATF3の肝臓糖代謝調節メカニズムの解明
- 2011 - 2013 セロトニンによる黒毛和種牛の遺伝子多型に対応した脂肪交雑制御機構の解明
Papers (35):
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Hitoshi Watanabe, Shun-Ichiro Asahara, Jinsook Son, Wendy M McKimpson, Rafael de Cabo, Domenico Accili. Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation. PloS one. 2024. 19. 2. e0297555
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Hitoshi Watanabe, Wen Du, Jinsook Son, Lina Sui, Shun-Ichiro Asahara, Irwin J Kurland, Taiyi Kuo, Takumi Kitamoto, Yasutaka Miyachi, Rafael de Cabo, et al. Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes. Science translational medicine. 2023. 15. 681. eabq4126
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Yuka Inaba, Emi Hashiuchi, Hitoshi Watanabe, Kumi Kimura, Yu Oshima, Kohsuke Tsuchiya, Shin Murai, Chiaki Takahashi, Michihiro Matsumoto, Shigetaka Kitajima, et al. The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice. Nature Communications. 2023. 14. 1
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Wen Du, Junqiang Wang, Taiyi Kuo, Liheng Wang, Wendy M. McKimpson, Jinsook Son, Hitoshi Watanabe, Takumi Kitamoto, Yun-Kyoung Lee, Remi J. Creusot, et al. Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals. Journal of Clinical Investigation. 2022
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Takumi Kitamoto, Yun-Kyoung Lee, Nishat Sultana, Hitoshi Watanabe, Wendy M. M, Kimpson, Wen Du, Jason Fan, Bryan Diaz, Hua V. Lin, et al. Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes. Molecular Metabolism. 2022. 101624-101624
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MISC (26):
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Watanabe H, Rose M, Kanayama Y, Shirakawa H, Aso H. Energy homeostasis by peripheral serotonin. Serotonin. 2017
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長澤裕哉, 盛田彰太郎, 日高湧介, 鈴木京, 渡邉一史, 渡邊康一, 大和田修一, 野地智法, 北澤春樹, 今村守一, et al. ウシ腸管M細胞における解糖系酵素アルドラーゼAの合成と分泌. 日本獣医学会学術集会講演要旨集. 2014. 157th. 321
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住吉敬介, 渡邉一史, 齋藤遼, 中野辰也, 長澤裕哉, 陳香凝, 岡田夏実, 渡邊康一, 野地智法, 麻生久. セロトニン腹腔内投与が高脂肪飼料摂取マウスの腸管セロトニン分泌細胞に与える影響. 日本畜産学会大会講演要旨. 2014. 118th. 148
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長澤裕哉, 盛田彰太郎, 日高湧介, 渡邉一史, 渡邊康一, 大和田修一, 北澤春樹, 今村守一, 横山隆, 堀内基広, et al. ウシパイエル板M細胞における解糖系酵素アルドラーゼAを介した異常型プリオン蛋白質取り込み機構. 日本畜産学会大会講演要旨. 2014. 118th. 108
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陳香凝, 長澤裕哉, 渡邉一史, 齋藤遼, 住吉敬介, 岡田夏美, 佐藤勝祥, 渡邊康一, 野地智法, 麻生久. マウス褐色脂肪細胞株の樹立. 日本畜産学会大会講演要旨. 2014. 118th. 155
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Education (2):
- 2008 - 2013 Tohoku University Graduate School of Agricultural Science
- 2004 - 2008 Tohoku University Faculty of Agriculture
Work history (6):
Awards (7):
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