Kazuhisa Murai

ムライカズヒサ | Kazuhisa Murai

Affiliation and department：

Research field (6)： Immunology , Tumor biology , Virology , Molecular biology , Cell biology , Gastroenterology

Research theme for competitive and other funds (7)：

2024 - 2027 B型肝炎ウイルスRNAを制御する宿主因子の機能解析
2023 - 2026 がん細胞代謝の理解に基づく肝がん免疫抑制機構の本態解明
2023 - 2026 新規モニタリング法の確立によるB型肝炎ウイルスを完全駆除する薬物の探索と同定
2022 - 2024 シングルセルマルチオミックス解析による肝がん微小環境の解明
2020 - 2024 Investigation on Molecular Mechanisms of Liver Diseases Caused by Hepatitis B and D Viruses Coinfection

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Papers (24)：

Mika Yoshita, Masaya Funaki, Tetsuro Shimakami, Masaki Kakuya, Kazuhisa Murai, Saiho Sugimoto, Shotaro Kawase, Koji Matsumori, Taro Kawane, Tomoki Nishikawa, et al. High-Throughput Screening of Antiviral Compounds Using a Recombinant Hepatitis B Virus and Identification of a Possible Infection Inhibitor, Skimmianine. Viruses. 2024. 16. 8. 1346-1346
Ying-Yi Li, Kazuhisa Murai, Junyan Lyu, Masao Honda. Roles Played by DOCK11, a Guanine Nucleotide Exchange Factor, in HBV Entry and Persistence in Hepatocytes. Viruses. 2024. 16. 5
Junyan Lyu, Hikari Okada, Hajime Sunagozaka, Kazunori Kawaguchi, Tetsuro Shimakami, Kouki Nio, Kazuhisa Murai, Takayoshi Shirasaki, Mika Yoshida, Kuniaki Arai, et al. Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction-associated steatohepatitis. Hepatology communications. 2024. 8. 5
Mayuko Ide, Noriko Tabata, Yuko Yonemura, Kazuhisa Murai, Ying Wang, Atsuya Ishida, Masao Honda, Shuichi Kaneko, Satoru Ito, Hiroshi Yanagawa. Hepatitis B virus evades the immune system by suppressing the NF-κB signaling pathway with DENND2A. Microbiology spectrum. 2024. 12. 3. e0378523
Ryogo Shimizu, Kazuhisa Murai, Kensuke Tanaka, Yuga Sato, Naho Takeda, Saki Nakasyo, Takayoshi Shirasaki, Kazunori Kawaguchi, Tetsuro Shimakami, Kouki Nio, et al. Nucleos(t)ide analogs for hepatitis B virus infection differentially regulate the growth factor signaling in hepatocytes. Hepatology Communications. 2024. 8. 1

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MISC (36)：

Tetsuhiro Shimode, Kazunori Kawaguchi, Noriaki Orita, Kouki Nio, Hikari Okada, Kazuhisa Murai, Tetsuro Shimakami, Kuniaki Arai, Taro Yamashita, Yoshio Sakai, et al. LIVER SINUSOIDAL ENDOTHELIAL CELLS AFFECT HEPATITIS B VIRUS REPLICATION IN VIRUS-INFECTED HEPATOCYTES VIA THE AKT-mTOR PATHWAY. HEPATOLOGY. 2022. 76. S269-S270
Kazuhisa Murai, Masao Honda, Takayoshi Shirasaki, Shuichi Kaneko. IDENTIFICATION OF A HOST FACTOR FOR THE IMPROVEMENT OF IMMUNE CHECKPOINT BLOCKADE THERAPY FOR HEPATOCELLULAR CARCINOMA. HEPATOLOGY. 2019. 70. 808A-809A
Kazuhisa Murai, Masao Honda, Tetsuro Shimakami, Takayoshi Shirasaki, Hirofumi Misu, Toshinari Takamura, Shuichi Kaneko. INDUCTION OF SELENOPROTEIN P mRNA DURING HEPATITIS C VIRUS INFECTION INHIBITS RIG-I-MEDIATED ANTIVIRAL IMMUNITY. HEPATOLOGY. 2019. 70. 79A-79A
Souma Yamanaka, Masao Honda, Takayoshi Shirasaki, Tetsuro Shimakami, Ryosuke Shimizu, Kazuhisa Murai, Miwako Narita, Hirofumi Misu, Toshinari Takamura, Taro Yamashita, et al. A LIVER-DERIVED SECRETORY PROTEIN, LECT2, RESTORES THE IMPAIRED PLASMACYTOIDDENDRITIC CELLS FUNCTION BY HBV AND PROTECTS HEPATOCYTES AGAINST HBV INFECTION. HEPATOLOGY. 2019. 70. 616A-617A
Takayoshi Shirasaki, Masao Honda, Kazuhisa Murai, Tetsuro Shimakami, Hirofumi Misu, Toshinari Takamura, Shuichi Kaneko. A Liver-Derived Secretory Protein, LECT2, Enhances the Innate Immune Response and Suppresses RIG-I Mediated Virus Infection. HEPATOLOGY. 2018. 68. 588A-589A

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Patents (5)：

Books (1)：

Education (1)：

Professional career (1)：

Awards (12)：

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Association Membership(s) (1)：

THE JAPAN SOCIETY OF HEPATOLOGY

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