Sakoda Yukimi

サコダユキミ | Sakoda Yukimi

Research keywords (2)： cancer immuntherapy , CAR-T細胞療法

Research theme for competitive and other funds (10)：

2022 - 2025 Development of next-generation CAR-NK cell immunotherapy against solid tumors
2021 - 2025 Mechanistic analysis of novel CAR-T cell therapy against solid tumors
2019 - 2022 Next generation CAR-T cell therapy for malignant melanoma
2016 - 2020 Cancer immunology research to enhance therapeutic effects of immune checkpoint blockade
2016 - 2019 Engineering CAR T cells for improved function against solid tumors

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Papers (24)：

Keisuke Ohta, Yukimi Sakoda, Keishi Adachi, Taro Shinozaki, Masao Nakajima, Hiroyuki Yasuda, Hiroaki Nagano, Koji Tamada. Therapeutic Efficacy of IL7/CCL19-Expressing CAR-T Cells in Intractable Solid Tumor Models of Glioblastoma and Pancreatic Cancer. Cancer Research Communications. 2024. 4. 9. 2514-2524
Takahiro Sasaki, Yukimi Sakoda, Keishi Adachi, Yoshihiro Tokunaga, Koji Tamada. Therapeutic effects of anti-GM2 CAR-T cells expressing IL-7 and CCL19 for GM2-positive solid cancer in xenograft model. Cancer Medicine. 2023. 12. 11. 12569-12580
Yoshihiro Tokunaga, Takahiro Sasaki, Shunsuke Goto, Keishi Adachi, Yukimi Sakoda, Koji Tamada. Enhanced Antitumor Responses of Tumor Antigen-Specific TCR T Cells Genetically Engineered to Produce IL7 and CCL19. Molecular cancer therapeutics. 2022. 21. 1. 138-148
Shunsuke Goto, Yukimi Sakoda, Keishi Adachi, Yoshitaka Sekido, Seiji Yano, Masatoshi Eto, Koji Tamada. Enhanced anti-tumor efficacy of IL-7/CCL19-producing human CAR-T cells in orthotopic and patient-derived xenograft tumor models. Cancer Immunology, Immunotherapy. 2021. 70. 9. 2503-2515
Jun-Ich Mori, Keishi Adachi, Yukimi Sakoda, Takahiro Sasaki, Shunsuke Goto, Hiroaki Matsumoto, Yoji Nagashima, Hideyasu Matsuyama, Koji Tamada. Anti-tumor efficacy of human anti-c-met CAR-T cells against papillary renal cell carcinoma in an orthotopic model. Cancer science. 2021. 112. 4. 1417-1428

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MISC (28)：

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Books (1)：

Lectures and oral presentations (16)：

T-cell therapyの新展開ヒト悪性中皮腫同所移植および膵癌PDXマウスモデルを用いたIL-7/CCL19産生型ヒトCAR-T細胞による抗腫瘍効果の検討
(日本がん免疫学会総会プログラム・抄録集 2020)
The role of HVEM co-signal pathway in murine experimental autoimmune uveitis
(Japanese Society for Immunology 2013)
Redirecting gene-modified T cells toward various types of cancer using tagged antibodies
(Japan-Australia Hematology Consortium 2013)
Redirecting gene-modified T cells toward various cancer types using tagged antibody
(Keystone Symposia Cancer Immunology and Immunotherapy 2013)
標識抗原を認識する新規キメラ抗原受容体を利用したがん免疫療法
(がん免疫学会 2012)

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Association Membership(s) (1)：

がん免疫学会

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