Rchr
J-GLOBAL ID：201801005666935519
Update date: Jun. 23, 2024
Masuno Hiroyuki
マスノ ヒロユキ | Masuno Hiroyuki
Affiliation and department：
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (3)：
- 2015 - 2018 Structure activity relationship study of bile acid derivatives to development of novel vitamin D receptor ligand
- 2006 - 2008 Medicinal chemistry based peptides against intractable disease including AIDS. Cancer and rheumatoid arthritis
- 2006 - 2007 胆汁酸誘導体のビタミンD受容体アゴニスト活性の構造生物学的解析
Papers (33)：
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Ryosuke Ishida, Nagomi Kurebayashi, Hiroto Iinuma, Xi Zeng, Shuichi Mori, Masami Kodama, Takashi Murayama, Hiroyuki Masuno, Fumi Takeda, Masatoshi Kawahata, et al. A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European Journal of Medicinal Chemistry. 2023. 262. 115910-115910
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Shigeru Yamada, Hiroyuki Masuno, Hiroyuki Kagechika, Aya Tanatani, Yasunari Kanda. A Novel Lithocholic Acid Derivative Upregulates Detoxification-Related Genes in Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2022. 45. 11. 1720-1724
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Tsuyoshi Oikawa, Shinya Fujii, Shuichi Mori, Hiroyuki Masuno, Emiko Kawachi, Hiroyuki Kagechika. Structural Development of Silicon-Containing Retinoids: Structure-Activity Relationship Study of the Hydrophobic Pharmacophore of Retinobenzoic Acids Using Silyl Functionalities. CHEMMEDCHEM. 2022. 17. 12
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Ayana Yoshihara, Haru Kawasaki, Hiroyuki Masuno, Koki Takada, Nobutaka Numoto, Nobutoshi Ito, Naoya Hirata, Yasunari Kanda, Michiyasu Ishizawa, Makoto Makishima, et al. Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists. BIOMOLECULES. 2022. 12. 1
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Shinya Fujii, Eriko Kikuchi, Honoka Suzuyama, Yuko Watanabe, Mari Ishigami-Yuasa, Hiroyuki Masuno, Takayasu Mori, Kiyoshi Isobe, Shinichi Uchida, Hiroyuki Kagechika. Structural Development of Salicylanilide-Based SPAK Inhibitors as Candidate Antihypertensive Agents. CHEMMEDCHEM. 2021. 16. 18. 2817-2822
ｍore...
MISC (1)：
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K Yamamoto, H Masuno, S Yamada. Three-dimensional structure-activity relationship of vitamin D based on computational and synthetic chemistries. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN. 2001. 59. 2. 131-141
Patents (5)：
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