Rchr
J-GLOBAL ID：201801005688186048
Update date: Oct. 07, 2024
Yashiro Takuya
ヤシロ タクヤ | Yashiro Takuya
Affiliation and department：
Job title：
Associate Professor
Research field (2)：
Immunology
, Food sciences
Research keywords (2)：
Immunology
, Food function
Research theme for competitive and other funds (4)：
- 2022 - 2025 Effect of psychological stress on group2 innate lymphoid cell-dependent allergic diseases
- 2020 - 2023 Molecular mechanisms and physiological significance of short chain fatty acid- and polyunsaturated fatty acid-mediated regulation of mast cell function
- 2019 - 2022 Immunosuppressive function of unsaturated fatty acid produced by lactic acid bacteria.
- 2017 - 2019 Effects of polyphenol intake on RALDH2 expression and intestinal immunity
Papers (42)：
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Miki Ando, Kazuki Nagata, Ryuki Takeshita, Naoto Ito, Sakura Noguchi, Natsuki Minamikawa, Naoki Kodama, Asuka Yamamoto, Takuya Yashiro, Masakazu Hachisu, et al. The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling. Frontiers in Immunology. 2024. 15
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Kazuki Nagata, Daisuke Ando, Tsubasa Ashikari, Kandai Ito, Ryosuke Miura, Izumi Fujigaki, Yuki Goto, Miki Ando, Naoto Ito, Hibiki Kawazoe, et al. Butyrate, Valerate, and Niacin Ameliorate Anaphylaxis by Suppressing IgE-Dependent Mast Cell Activation: Roles of GPR109A, PGE2, and Epigenetic Regulation. The Journal of Immunology. 2024. 212. 5. 771-784
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Seidai Takasawa, Kosuke Kimura, Masato Miyanaga, Takuya Uemura, Masakazu Hachisu, Shinichi Miyagawa, Abdelaziz Ramadan, Satoru Sukegawa, Masaki Kobayashi, Seisuke Kimura, et al. The powerful potential of amino acid menthyl esters for anti-inflammatory and anti-obesity therapies. Immunology. 2024. 173. 1. 76-92
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Takuya Yashiro, Kazuyo Moro. Crossing the valley of death: Toward translational research regarding ILC2. Allergology International. 2023. 72. 2. 187-193
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Kazuki Nagata, Sanae Araumi, Daisuke Ando, Naoto Ito, Miki Ando, Yuki Ikeda, Miki Takahashi, Sakura Noguchi, Yayoi Yasuda, Nobuhiro Nakano, et al. Kaempferol Suppresses the Activation of Mast Cells by Modulating the Expression of FcεRI and SHIP1. International journal of molecular sciences. 2023. 24. 6
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MISC (13)：
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安藤実希, 長田和樹, 兒玉直輝, 八代拓也, 伊藤直人, 八須匡和, 市原学, 山本雅之, 岸野重信, 小川順, et al. The effect of the gut microbial metabolite of γ-linolenic acid, 10-oxo-cis-6, trans-11-octadecadienoic acid, relieves the symptoms of colitis via the NRF2 pathway in dendritic cells. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
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高沢青大, 木村恒介, 八須匡和, 小林正樹, 木村成介, 松井健二, 西山千春, 八代拓也, 樋上賀一, 宮川信一, et al. Amino acid menthyl esters exhibit superior anti-inflammatory and anti-obesity therapies. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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安藤実希, 長田和樹, 兒玉直輝, 八代拓也, 伊藤直人, 八須匡和, 小川順, 西山千春. 多価不飽和脂肪酸の腸内乳酸菌代謝産物γKetoCの炎症性腸疾患改善作用におけるNRF2の寄与. 日本食品免疫学会学術大会要旨集. 2022. 18th
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兒玉直輝, 岡田光, 八代拓也, 長田和樹, 八須匡和, 市原学, 西山千春. Immunosuppressive effects of rose-derived compound damascone-β and the molecular mechanism. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
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伊藤直人, 坂田文弥, 八須匡和, 長田和樹, 伊藤朋香, 中野信浩, 八代拓也, 西山千春. The roles of PU.1/IRF4 in the gene expression of CCL17/TARC in mammal DCs, and the effects of PU.1 siRNA on asthma model mice. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
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Books (2)：
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免疫生物学
南江堂 2019 ISBN:9784524251155
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分子細胞免疫学
エルゼビア・ジャパン 2018 ISBN:9784860349172
Lectures and oral presentations (104)：
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レスベラトロールポリフェノールの免疫調節機構
(第22回日本抗加齢医学会 2022)
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分岐鎖型短鎖脂肪酸によるマスト細胞依存性アレルギー炎症の抑制
(日本農芸化学会2020年度大会 2020)
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シソ葉香気成分による免疫抑制効果
(日本農芸化学会2020年度大会 2020)
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サリチルアルデヒドによる免疫細胞の機能調節
(日本農芸化学会2020年度大会 2020)
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ケンフェロールはAhRアンタゴニスト活性を介して腸管樹状細胞のRALDH2発現を促進する
(日本農芸化学会2020年度大会 2020)
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Education (2)：
- - 2011 The University of Tokyo Graduate School, Division of Agricultural Science Department of Applied Biological Chemistry
- - 2006 Meiji University Faculty of Agriculture Department of Life Science
Professional career (1)：
- Ph. D. (The University of Tokyo)
Work history (1)：
- 2024/04 - 現在 Osaka University Graduate School of Medicine Associate Professor
Awards (3)：
- 2020/03/25 - Tadamitsu Kishimoto International Travel Award
- 2020/03/05 - 日本農芸化学会2020年度大会優秀発表賞
- 2020/02/05 - BioLegend/Tomy Digital Biology LEGEND Travel Award
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