Rchr
J-GLOBAL ID：201801005721925803   Update date: Feb. 05, 2024

Sumiyo Morita

Sumiyo Morita
Research field  (1)： Genomics
Research theme for competitive and other funds  (8)：
  • 2022 - 2025 狙ったDNAが過剰メチル化された疾患モデル動物作製法の開発
  • 2020 - 2023 Histone methyltransferase KMT2 mutation-induced epigenomic abnormalities and endometrial cancer development and progression
  • 2019 - 2022 The role of imprinted genes in metabolic regulation and their evolutionary significance.
  • 2019 - 2022 Generation of parthenogenetic mice by epigenome editing
  • 2017 - 2020 A new therapeutic strategy for autoimmune diseases through epigenome editing
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Papers (53)：
  • Sumiyo Morita, Takuro Horii, Mika Kimura, Ryosuke Kobayashi, Hiroki Tanaka, Hidetaka Akita, Izuho Hatada. A Lipid Nanoparticle-Based Method for the Generation of Liver-Specific Knockout Mice. International Journal of Molecular Sciences. 2023. 24. 18. 14299-14299
  • Ryosuke Kobayashi, Reika Kawabata-Iwakawa, Jumpei Terakawa, Makoto Sugiyama, Sumiyo Morita, Takuro Horii, Izuho Hatada. Aberrant activation of estrogen receptor-α signaling in Mettl14-deficient uteri impairs embryo implantation. The FASEB Journal. 2023. 37. 8
  • Takuro Horii, Sumiyo Morita, Mika Kimura, Izuho Hatada. Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system. Epigenetics & chromatin. 2022. 15. 1. 40-40
  • Ryosuke Kobayashi, Reika Kawabata-Iwakawa, Makoto Sugiyama, Tetsunari Oyama, Masato Ohtsuka, Takuro Horii, Sumiyo Morita, Masahiko Nishiyama, Izuho Hatada. Multiplexed genome editing by in vivo electroporation of Cas9 ribonucleoproteins effectively induces endometrial carcinoma in mice. International journal of cancer. 2022. 152. 11. 2331-2337
  • Takuro Horii, Sumiyo Morita, Shinjiro Hino, Mika Kimura, Yuko Hino, Hiroshi Kogo, Mitsuyoshi Nakao, Izuho Hatada. Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome. Genome Biology. 2020. 21. 1
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MISC (89)：
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