Research field (1)：
Pharmaceuticals - health and biochemistry
Research keywords (2)：
Environmental Toxicology
, Lipid Biology
Research theme for competitive and other funds (3)：
2023 - 2027 雌性生殖を制御する膜リン脂質代謝酵素の機能解析
2009 - 2012 Studies on novel mechanisms of environmental chemicals-induced toxicity using arachidonate-metabolizing enzyme genetically modified mice
2009 - 2010 Analysis of membrane-associated calcium-independent phospholipase A_2 (iPLA_<2γ>) in vivo.
Papers (17)：
Satoko Nakayama, Emiko Yoda, Saki Yamashita, Yuka Takamatsu, Yasutomo Suzuki, Yukihiro Kondo, Shuntaro Hara. Knockdown of iPLA2γ enhances cisplatin-induced apoptosis by increasing ROS-dependent peroxidation of mitochondrial phospholipids in bladder cancer cells. Free radical biology & medicine. 2024
Hiroshi Kuwata, Eriko Nakatani, Yuki Tomitsuka, Tsubasa Ochiai, Yuka Sasaki, Emiko Yoda, Shuntaro Hara. Deficiency of long-chain acyl-CoA synthetase 4 leads to lipopolysaccharide-induced mortality in a mouse model of septic shock. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 12. e23330
Tetsuya Hirabayashi, Mai Kawaguchi, Sayaka Harada, Misa Mouri, Rina Takamiya, Yoshimi Miki, Hiroyasu Sato, Yoshitaka Taketomi, Kohei Yokoyama, Tetsuyuki Kobayashi, et al. Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups. Cell reports. 2023. 42. 2. 111940-111940
Hiroshi Kuwata, Yuki Tomitsuka, Emiko Yoda, Shuntaro Hara. Role of ACSL4 in the chemical-induced cell death in human proximal tubule epithelial HK-2 cells. Bioscience reports. 2022. 42. 2
