2020 - 2025 Novel strategy to treat intractable CNS disorders, utilizing the properties of BBB-composing cells
2021 - 2024 Mechanism of breakdown of blood-brain barrier/blood-nerve barrier in neuroimmunological disorder
2017 - 2022 血液脳関門/血液神経関門を操作する新規モノクローナル抗体の作製
2018 - 2021 Discovery of new drug target modifiying the function of blood-brain barrier and blood-nerve barrier
2012 - 2015 Investigation into the mechanism of the blood-nerve barrier disruption in chronic inflammatory demyelinating polyradiculoneuropathy and multifocal motor neuropathy
2010 - 2011 The effect of advanced glycation end-products on blood-nerve barrier
2007 - 2008 Analysis of the function of the endothelial cells forming blood-nerve barrier
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Papers (74):
Masaya Honda, Fumitaka Shimizu, Ryota Sato, Masayuki Nakamori. Contribution of Complement, Microangiopathy and Inflammation in Idiopathic Inflammatory Myopathies. Journal of neuromuscular diseases. 2023
Julien Cicero, Sarah Trouvilliez, Martine Palma, Gaetan Ternier, Laurine Decoster, Eloise Happernegg, Nicolas Barois, Alexandre Van Outryve, Lucie Dehouck, Roland P Bourette, et al. ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Experimental hematology & oncology. 2023. 12. 1. 104-104
Ryota Sato, Fumitaka Shimizu, Motoi Kuwahara, Yoichi Mizukami, Kenji Watanabe, Toshihiko Maeda, Yasuteru Sano, Yukio Takeshita, Michiaki Koga, Susumu Kusunoki, et al. Autocrine TNF-α Increases Penetration of Myelin-Associated Glycoprotein Antibodies Across the Blood-Nerve Barrier in Anti-MAG Neuropathy. Neurology(R) neuroimmunology & neuroinflammation. 2023. 10. 3
Joe Nemoto, Fumitaka Shimizu, Toshihiko Maeda, Hideaki Nishihara, Michiaki Koga, Takashi Kanda. [Clinical features of 8 patients with multifocal motor neuropathy in the long-term follow-up]. Rinsho shinkeigaku = Clinical neurology. 2023. 63. 4. 209-213