Hiroto Kikuchi

Research field (6)： Biophysics , Biophysics , Computational science , Bio-, chemical, and soft-matter physics , Basic physical chemistry , Structural biochemistry

Research theme for competitive and other funds (6)：

2014 - 2017 基盤研究(C)[研究代表者]「ヒトには効くがバクテリアには効かない痛風薬 -酵素薬剤相互作用のダイナミクス-」
2011 - 2013 基盤研究(C)[研究代表者]「キサンチン酸化還元酵素における阻害剤の研究 -「鍵と鍵穴」のドグマを超えて-」
2010 - 2013 基盤研究(C)[研究分担者]「生体分子の量子ダイナミクス:その理論的解明と制御」
2004 - 2008 基盤研究(A) [研究分担者] 「モリブデン金属酵素の微細構造と水酸化反応機構・蛋白質揺らぎの解明」
1999 - 2001 萌芽的研究 [研究分担者] 「基準振動解析による蛋白質の構造の必然性の解明-光合成系を例にして」

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Papers (36)：

Hiroto Kikuchi. Redshifting and Blueshifting of β82 Chromophores in the Phycocyanin Hexamer of Porphyridium purpureum Phycobilisomes Due to Linker Proteins. Life. 2022. 12. 11. 1833-1833
Hiroto Kikuchi. Functional roles of the hexamer structure of C-phycocyanin revealed by calculation of absorption wavelength. FEBS Open Bio. 2020. 10. 11. 1-9
H.Kikuchi. A Method to Calculate Functions of the Product of G and F used in Wilson’s GF Matrix method. IJTSRD. 2018. 2. 4. 2516-2519
岡本研, 菊地浩人. キサンチン酸化還元酵素-物理学から臨床医学まで-. 日本医科大学基礎科学紀要. 2018. 46. 46. 37-69
Hiroshi Fujisaki, Kiyoshi Yagi, Hiroto Kikuchi, Toshiya Takami, Gerhard Stock. Vibrational energy transport in acetylbenzonitrile described by an ab initio-based quantum tier model. CHEMICAL PHYSICS. 2017. 482. 86-92

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MISC (77)：

菊地浩人, 藤崎弘士. 分子動力学を用いたアセチルベンゾニトリルからクロロフォルム溶媒へのエネルギー移動の計算. 日本物理学会講演概要集(CD-ROM). 2019. 74. 2
菊地浩人, 藤崎弘士. 溶媒中のアセチルベンゾニトリルにおけるエネルギー移動:非平衡MDによる計算. 日本物理学会講演概要集(CD-ROM). 2018. 73. 2
岡本研, 菊地浩人. Xanthine Oxidoreductase : from physics to clinical medicine. 日本医科大学基礎科学紀要 = The Bulletin of liberal arts & sciences, Nippon Medical School. 2017. 46. 37-69
岡本研, 菊地浩人, 藤崎弘士, 古田忠臣, 西野武士. キサンチン酸化還元酵素基質結合ポケットの動的解析. 日本痛風・核酸代謝学会総会プログラム・抄録集. 2016. 49th. 78
Kikuchi H, Fujisaki H, Furuta T, Okamoto K, Nishino T. The gout medicine which has strong effects on mammalian XOR but not on bacterial XOR: dynamics of the interaction between enzime XOR and its inhibitor BOF. Meeting Abstracts of the Physical Society of Japan. 2016. 71. 0. 3119-3119

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Books (5)：

Antenna systems and energy transfer in cyanophyta and rhodophyta. In: Light-harvesting Antennas in Photosynthesis edited by B. R. Green and W. W. Parson. Advanced in Photosynthesis and Respiration: Series Editor Govindjee
Springer, The Netherlands 2003 ISBN:9780792363354
Structure and Function of Phycobilisome. In: Concepts in Photobiology: Photosynthesis and Photomorphogenesis edited by G. S. Singhal, G. Renger, S.K. Sopory, K-D. Irrgang and Govindjee
Springer, The Netherlands 1999 ISBN:9789401148320
Circadian cellular spatiotemporal organization conducted by simple Ca2+ oscillation, Neuroscience Research, Vol. 31, Suppl. 1
ELSEVIER, The Netherlands 1998
Functional meaning of the symmetry structure in phycobiliprotein aggregates. In: Proceeding of XIth International Congress on Photosynthesis: Mechanisms and Effects
Springer, The Netherlands 1998
Rigid domain in static and dynamic structures of proteins, Progress in Biophysics and Molecular Biology, Vol. 65, Suppl. 1
ELSEVIER, The Netherlands 1996

Work history (5)：

2007/04 - 現在 Nippon Medical School Medical School
2004/04 - 2007/03 Nippon Medical School Medical School
1996/04 - 2004/03 Nippon Medical School Medical School
1991/04 - 1996/03 Nippon Medical School Medical School
1990/04 - 1991/03 Waseda University School of Science and Engineering

Committee career (2)：

1994/10 - 1996/10 日本物理学会日本物理学会誌編集委員会新著紹介小委員会委員
1992/05 - 1993/04 日本物理学会生体物理分科世話人

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