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J-GLOBAL ID：201801005831778415   Update date: Apr. 04, 2024

Usui Tatsuya

Usui Tatsuya | Usui Tatsuya
Affiliation and department：
Tokyo University of Agriculture and Technology Institute of Agriculture, Division of Animal Life Science

About Tokyo University of Agriculture and Technology Institute of Agriculture, Division of Animal Life Science


Job title： Senior Assistant Professor
Other affiliations (2)：
Research field  (1)： Veterinary medicine
Research keywords  (7)： Organoid ,  Nonalcoholic steatohepatitis ,  獣医薬理学 ,  獣医学 ,  分子生物学 ,  がん ,  三次元培養
Research theme for competitive and other funds  (12)：
  • 2022 - 2025 Establishment of cat multiorgan organoid-on-a-chip system
  • 2020 - 2025 Evaluation of selective autophagy in non-alcoholic steatosis-related hepatocarcinogenesis rat model
  • 2020 - 2024 Exploratory research on novel diagnostic and therapeutic markers for mesothelioma
  • 2020 - 2024 Multidisciplinary research using urine-derived organoids: To overcome canine bladder cancer
  • 2018 - 2021 Exploring novel therapeutic target genes for dog prostate cancer using urine-derived 3D culture
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Papers (69)：
  • Ameen A Salahudeen, Jose A Seoane, Kanako Yuki, Amanda T Mah, Amber R Smith, Kevin Kolahi, Sean M De la O, Daniel J Hart, Jie Ding, Zhicheng Ma, et al. Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis. Cell reports. 2023. 42. 11. 113355-113355
  • Sumire Shimada, Mohamed Aboubakr, Mohamed Elbadawy, Tatsuya Usui, Kazuaki Sasaki, Minoru Shimoda. Biliary excretion and pharmacokinetics of several fluoroquinolones after intravenous injection in rabbits. The Journal of veterinary medical science. 2023. 85. 10. 1099-1105
  • Yomogi Shiota Sato, Mohamed Elbadawy, Kazuhiko Suzuki, Ryouichi Tsunedomi, Hiroaki Nagano, Yusuke Ishihara, Haru Yamamoto, Daigo Azakami, Tsuyoshi Uchide, Ryuji Fukushima, et al. Derivation of a new model of lung adenocarcinoma using canine lung cancer organoids for translational research in pulmonary medicine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023. 165. 115079-115079
  • Yomogi Sato, Mohamed Elbadawy, Kazuhiko Suzuki, Ryouichi Tsunedomi, Hiroaki Nagano, Yusuke Ishihara, Haru Yamamoto, Daigo Azakami, Tsuyoshi Uchide, Rina Nabeta, et al. Establishment of an experimental model of canine malignant mesothelioma organoid culture using a three-dimensional culture method. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023. 162. 114651-114651
  • Mohamed Elbadawy, Kiwamu Tanabe, Haru Yamamoto, Yusuke Ishihara, Maria Mochizuki, Amira Abugomaa, Hideyuki Yamawaki, Masahiro Kaneda, Tatsuya Usui, Kazuaki Sasaki. Evaluation of the efficacy of mitochondrial fission inhibitor (Mdivi-1) using non-alcoholic steatohepatitis (NASH) liver organoids. Frontiers in pharmacology. 2023. 14. 1243258-1243258
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MISC (28)：
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Patents (8)：
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Books (2)：
  • 肺がんオルガノイド・血管内皮細胞共培養システムを用いた細胞間相互作用メカニズムの解明
    北隆館 2018
  • 三次元マウス肺がんモデルの確立とがん・血管内皮連関機構の解明
    北隆館 2018
Lectures and oral presentations  (12)：
  • Exploring for new biomarkers using liver organoids derived from nonalcoholic steatohepatitis (NASH) model mice
    (2020)
  • Establishment of 2.5D bladder cancer organoid culture method
    (2020)
  • Establishment of the method of three-dimensional organoid culture derived from liver tissues of non-alcoholic steatohepatitis (NASH) model mice
    (2020)
  • イヌ膀胱がんオルガノイドを用いた新規分子標的薬の探索
    (第93回日本薬理学会年会 2020)
  • Growth inhibitory effect of dietary polyphenol antioxidant in human colorectal stem cells
    (2020)
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Education (2)：
  • 2010 - 2013 北里大学 獣医畜産学研究科 獣医学専攻
  • 2004 - 2010 北里大学 獣医畜産学部 獣医学科
Professional career (1)：
  • 獣医学博士 (北里大学)
Work history (4)：
  • 2013/11/01 - 2017/08/31 山口大学 共同獣医学部・獣医毒性学 助教
  • 2015/04/01 - 2015/09/30 スタンフォード大学 医学部 客員教員
  • 2013/04/01 - 2013/10/31 日本学術振興会 特別研究員(PD・農学)
  • 2011/04/01 - 2013/03/31 日本学術振興会 特別研究員(DC1・農学)
Awards (4)：
  • 2018/07 - 日本毒性学会 第8回日本毒性学会技術賞 新規三次元培養法,エアリキッドインターフェイス(ALI)オルガノイド培養法の確立と毒性試験への応用
  • 2016/06 - 第31回 二宮善基記念賞
  • 2012/03 - 平成24年度 獣医学奨励賞 血管炎症性障害を介して高血圧症進展を制御する新規カルモジュリン関連蛋白質の探索と機能解析
  • 2009/09 - 第2回 日本比較薬理学・毒性学会 奨励賞
Association Membership(s) (5)：
THE JAPANESE SOCIETY OF TOXICOLOGY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE SOCIETY OF VETERINARY SCIENCE
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