Rchr
J-GLOBAL ID:201801005867388915   Update date: May. 28, 2024

LU YONGGANG

ル ヨンガン | LU YONGGANG
Affiliation and department:
Job title: Specially Appointed Associate Professor
Research field  (3): Molecular biology ,  Genetics ,  Developmental biology
Research keywords  (3): Genetic Biology ,  Molecular Biology ,  Developmental Biology
Research theme for competitive and other funds  (3):
  • 2024 - 2027 哺乳類の精子と卵子の融合の分子メカニズムの解明
  • 2022 - 2024 Deciphering the cellular and molecular mechanisms underlying mammalian sperm-egg fusion
  • 2018 - 2022 Discovery of genes essential for male fertility using CRISPR/Cas9-based genome editing technology
Papers (23):
  • Shunsuke Nishio, Chihiro Emori, Benjamin Wiseman, Dirk Fahrenkamp, Elisa Dioguardi, Sara Zamora-Caballero, Marcel Bokhove, Ling Han, Alena Stsiapanava, Blanca Algarra, et al. ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell. 2024. 187. 6. 1440-1459.e24
  • Yo Ogawa, Yonggang Lu, Daiji Kiyozumi, Hsin-Yi Chang, Masahito Ikawa. CRISPR/Cas9-mediated genome editing reveals seven testis-enriched transmembrane glycoproteins dispensable for male fertility in mice. Andrology. 2023
  • Shunsuke Nishio, Chihiro Emori, Benjamin Wiseman, Dirk Fahrenkamp, Elisa Dioguardi, Sara Zamora-Caballero, Marcel Bokhove, Ling Han, Alena Stsiapanava, Yonggang Lu, et al. Architecture of the vertebrate egg coat and structural basis of the ZP2 block to polyspermy. 2023
  • Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa. 1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 8. e2207263120
  • Yonggang Lu, Ippei Nagamori, Hisato Kobayashi, Kanako Kojima-Kita, Kenjiro Shirane, Hsin-Yi Chang, Toru Nishimura, Takayuki Koyano, Zhifeng Yu, Julio M. Castañeda, et al. ADAD2 functions in spermiogenesis and piRNA biogenesis in mice. Andrology. 2023. 11. 4. 698-709
more...
Education (3):
  • 2013 - 2016 The University of Newcastle, Australia Priority Research Centre for Reproductive Science Doctor of Philosophy (Biological Sciences)
  • 2012 - 2012 The University of Newcastle, Australia Priority Research Centre for Reproductive Science Bachelor of Biotechnology (Honours)
  • 2010 - 2011 The Univeristy of Newcastle, Australia School of Environmental and Life Sciences Bachelor of Biotechnology
Professional career (1):
  • PhD (Biological Sciences)
Work history (5):
  • 2023/06 - 現在 Osaka University Research Institute for Microbial Diseases Specially Appointed Associate Professor (co-current)
  • 2023/06 - 現在 Osaka University Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe) Specially Appointed Associate Professor (full-time)
  • 2021/08 - 2023/06 Osaka University Immunology Frontier Research Center (WPI-IFReC) Specially Appointed Assistant Professor (full-time)
  • 2020/04 - 2021/08 Osaka University Research Institute for Microbial Diseases Specially Appointed Assistant Professor (full-time)
  • 2017/10 - 2020/03 Osaka University Research Institute for Microbial Diseases Specially Appointed Researcher (full-time)
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