Toshie Kai

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://www.fbs.osaka-u.ac.jp/labs/kai/ , http://www.fbs.osaka-u.ac.jp/labs/kai/en/

Research field (2)： Developmental biology , Molecular biology

Research theme for competitive and other funds (5)：

2021 - 2026 非ドメイン型タンパク質によるヌアージュ形成制御の遺伝学的解析
2021 - 2024 Tudorドメイン蛋白質群が関与するpiRNA生合成とヌアージュ形成機構の解明
2020 - 2022 生殖幹細胞の全能性を保障する多階層的な非ゲノム情報の複製機構の解明
2018 - 2021 Elucidation of piRNA biogenesis involving Tudor domain proteins
2014 - 2018 Molecular mechanism of germline maintenance and differentiation via long-noncoding RNAs

Papers (37)：

Toshie Kai, Jinglan Zheng, Taichiro Iki. Paralog-dependent Specialization of Paf1C subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila. 2024
Fengmei Xu, Ritsuko Suyama, Toshifumi Inada, Shinichi Kawaguchi, Toshie Kai. HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis. 2024
Ritsuko Suyama, Nicolas Cetraro, Joanne Y. Yew, Toshie Kai. Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways. Communications Biology. 2023
Yuxuan Lin, Ritsuko Suyama, Shinichi Kawaguchi, Taichiro Iki, Toshie Kai. Tejas functions as a core component in nuage assembly and precursor processing in Drosophila piRNA biogenesis. The Journal of cell biology. 2023. 222. 10
Taichiro Iki, Shinichi Kawaguchi, Toshie Kai. miRNA/siRNA-directed pathway to produce noncoding piRNAs from endogenous protein-coding regions ensures Drosophila spermatogenesis. Science advances. 2023. 9. 29. eadh0397

ｍore...

MISC (4)：

須山律子, 甲斐歳惠. Non-membranous RNP condensates control the fate of germline cells. 実験医学. 2021. 39. 10
Amit Anand, Teo Yee Wei, Katsutomo Okamura, Toshie Kai. HP1a functions to suppress the evolutionarily fixed and telomeric transposons via piRNAs. GENES & GENETIC SYSTEMS. 2016. 91. 6. 331-331
Amit Anand, Toshie Kai. Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin Response. EMBO JOURNAL. 2014. 33. 6. 540-541
Ai Khim Lim, Liheng Tao, Toshie Kai. Post-transcriptional retroelement surveillance is mediated by piRNAs in Drosophila germline. MECHANISMS OF DEVELOPMENT. 2009. 126. S51-S51

Lectures and oral presentations (18)：

キャリアパス委員会主催ランチタイムセミナー2023
(第46回分子生物学会年会 2023)
Structure and function of a non-membrane organelle, nuage, in germline cells
(33rd Forum in DOJIN)
Molecular basis of nuage organization by Tejas and coordination for piRNA biogenesis in Drosophila
(2022 EMBO Workshop on PIWI Proteins and piRNAs 2022)
piRNAs and PIWI proteins
(EMBO Workshop)
Tudor Domain Proteins and Small Interfering RNAs Protects Germline Cells
(The International Conference of the Genetics Society of Korea 2017 2017)

ｍore...

Education (1)：

Professional career (1)：

Work history (11)：

2023/04 - 現在日本分子生物学会キャリアパス委員会
2021/04 - 現在 Osaka University Center for Global Initiatives Director of Student Mobility Unit
2015/10 - 現在 Osaka University Graduate School of Frontier Biosciences Professor
2020 - 2022/12 The 45th MBSJ organization committee Program committee chair
2011/01 - 2015/09 The National University of Singapore Department of Biological Science Adjunct Associate Professor

Show all

Awards (1)：

Association Membership(s) (3)：

日本発生生物学会 , 日本分子生物学会 , 日本RNA学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page