Rchr
J-GLOBAL ID:201801006022927120   Update date: Apr. 12, 2024

Fukunaga Koya

フクナガ コウヤ | Fukunaga Koya
Affiliation and department:
Research field  (3): Medical biochemistry ,  Veterinary medicine ,  Genomics
Research keywords  (5): Dog ,  Cattle ,  Human genomic diversity ,  pharmacokinetics ,  pharmacogenomics
Research theme for competitive and other funds  (5):
  • 2022 - 2025 牛のMHC領域のシークエンシングによる乳房炎抵抗性遺伝子の探索と新規防除法の開発
  • 2023 - 2025 生殖細胞系列 PGx バイオマーカーによる薬剤の体内 曝露量を予測するための PGx 関連遺伝子バリアント の大規模アノテーションデータベースの構築
  • 2017 - 2020 Genome wide association study to identify the susceptibility of staphylococcus aureus-induced mastitis in Holstein cattle and to estimate the risk
  • 2014 - 2018 The Project for Integrative Application of Human and Pathogen Genomic Information for Tuberculosis Control.
  • 2010 - 2011 イヌの抗てんかん薬の薬効に個体差を引き起こすCYP3Aファミリーの分子機構解析
Papers (41):
  • Koya Fukunaga, Eri Tsukagoshi, Ryosuke Nakamura, Kayoko Matsunaga, Takeshi Ozeki, Hideaki Watanabe, Akito Hasegawa, Natsumi Hama, Maiko Kurata, Yoshiko Mizukawa, et al. Association of HLA-A∗11:01, HLA-B∗39:01, and HLA-B∗56:03 with salazosulfapyridine-induced cutaneous adverse drug reactions. The Journal of Allergy and Clinical Immunology: In Practice. 2024
  • Koya Fukunaga, Eri Tsukagoshi, Maiko Kurata, Yoshiko Mizukawa, Hiroyuki Niihara, Eishin Morita, Yuko Watanabe, Yukie Yamaguchi, Hideaki Watanabe, Saeko Nakajima, et al. Differential Effects of HLA-B∗15:11 and HLA-A∗31:01 on Carbamazepine-Induced Cutaneous Adverse Reactions. The Journal of investigative dermatology. 2024. 144. 4. 908-911
  • Daichi Shigemizu, Koya Fukunaga, Akiko Yamakawa, Mutsumi Suganuma, Kosuke Fujita, Tetsuaki Kimura, Ken Watanabe, Taisei Mushiroda, Takashi Sakurai, Shumpei Niida, et al. The HLA-DRB1*09:01-DQB1*03:03 haplotype is associated with the risk for late-onset Alzheimer's disease in APOE [Formula: see text]4-negative Japanese adults. npj aging. 2024. 10. 1. 3-3
  • Alec W R Langlois, Ahmed El-Boraie, Jennie G Pouget, Lisa Sanderson Cox, Jasjit S Ahluwalia, Koya Fukunaga, Taisei Mushiroda, Jo Knight, Meghan J Chenoweth, Rachel F Tyndale. Genotyping, characterization, and imputation of known and novel CYP2A6 structural variants using SNP array data. Journal of human genetics. 2023
  • Tomonori Iyoda, Kanako Shimizu, Masami Kawamura, Jun Shinga, Takashi Watanabe, Koya Fukunaga, Taisei Mushiroda, Hideo Saka, Chiyoe Kitagawa, Shin-ichiro Shimamatsu, et al. Augmenting Granzyme B-Expressing NK Cells by Invariant NKT Ligand-Loaded APCs in Patients with Postoperative Early Stage Non-Small Cell Lung Cancer: Results of a Randomized Phase II Study. ImmunoHorizons. 2023. 7. 1. 1-16
more...
MISC (7):
  • 莚田 泰誠, 福永 航也. 【小麦依存性運動誘発アナフィラキシーの最新知見】小麦依存性運動誘発アナフィラキシーの疾患感受性遺伝子. アレルギーの臨床. 2022. 42. 11. 845-848
  • 「注目論文:Our Focus on Genetics」PKseqパネルとロングリードシークエンシングを用いたCYP2D6の新規ハプロタイプの同定とその機能解析. 2022
  • 薬物動態関連遺伝子の次世代シークエンス解析アップデート:薬物代謝酵素及び薬物トランスポーター遺伝子のアンプリコン・シークエンシングプラットフォーム,PKseqの開発. 2021
  • Registration of novel BoLA sequence in IPD-MHC detabase. 2020
  • Registration of novel CYP2D6 haplotypes in PharmVar. 2020
more...
Patents (2):
  • 薬物動態関連遺伝子の網羅的配列解析法とそれに使用 されるプライマーセット
  • 薬物の副作用関連遺伝子の配列解析方法とそれに使用されるプライマーセット
Lectures and oral presentations  (31):
  • Establishment of the pharmacogene variation database in 967 Japanese individuals using corePGseq panel
    (Human Genetics Asia 2023)
  • 薬剤性間質性肺疾患の発症に関連する遺伝子多型の探索
    (医療薬学会 2023)
  • ウシおよびヒトのMHCゲノムの多様性と感染症・食物性/薬物性アレルギーとの関連
    (日本獣医学会学術集会 2023)
  • CYP2C9基質薬物の代謝におけるCYP2C9*3の影響の比較
    (日本臨床薬理学会学術総会 2023)
  • 血漿中ボリコナゾール濃度と副作用の個人差に関与する因子の解析
    (日本小児遺伝学会学術集会 2023)
more...
Education (2):
  • 2008 - 2011 Azabu University
  • 2002 - 2008 Azabu University School of Veterinary Medicine Department of Veterinary Medicine
Work history (6):
  • 2023/04 - 現在 RIKEN Laboratory for Pharmacogenomics Research Scientist
  • 2022/10 - 2023/03 National Institute of Health Sciences Division of Medical Safety Science
  • 2018/04 - 2022/09 RIKEN Center for Integrative Medical Sciences Laboratory for Pharmacogenomics Research Scientist
  • 2013/04 - 2018/03 RIKEN Center for Integrative Medical Sciences Laboratory for Pharmacogenomics Research Scientist
  • 2012/04 - 2013/03 RIKEN
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Awards (1):
  • 2021/09 - 日本組織適合性学会 大会長賞
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