Rchr
J-GLOBAL ID：201801006042294990
Update date: May. 23, 2024
Tomohiro Fukaya
フカヤ トモヒロ | Tomohiro Fukaya
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Immunology
Research theme for competitive and other funds (5)：
- 2023 - 2026 形質細胞様樹状細胞の機能制御分子を標的とした新規免疫チェックポイント阻害剤の開発
- 2017 - 2020 IL-22結合タンパクによる皮膚炎症慢性化に対する制御機構の解明
- 2014 - 2017 CD4陽性通常型樹状細胞による自己免疫疾患の制御機構の解明
- 2010 - CD205陽性樹状細胞による免疫反応制御の解明
- 2007 - 経口免疫寛容における樹状細胞の役割の解明
Papers (28)：
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Uto T, Fukaya T, Mitoma S, Nishikawa Y, Tominaga M, Choijookhuu N, Hishikawa Y, Sato K. Clec4A4 Acts As A Negative Immune Checkpoint Regulator to Suppress Antitumor Immunity. Cancer immunology research. 2023. 11. 9. 1266-1279
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Fukaya T, Uto T, Mitoma S, Takagi H, Nishikawa Y, Tominaga M, Choijookhuu N, Hishikawa Y, Sato K. Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells. Cell Reports. 2023. 42. 5. 112431
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Yano K, Choijookhuu N, Ikenoue M, Fidya, Fukaya T, Sato K, Lee D, Taniguchi N, Chosa E, Nanashima A, et al. Spatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration. Scientific Reports. 2022. 12. 1. 11962
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Yotaro Nishikawa, Tomohiro Fukaya, Takehito Fukui, Tomofumi Uto, Hideaki Takagi, Junta Nasu, Noriaki Miyanaga, Dieter Riethmacher, Narantsog Choijookhuu, Yoshitaka Hishikawa, et al. Congenital Deficiency of Conventional Dendritic Cells Promotes the Development of Atopic Dermatitis-Like Inflammation. Frontiers in Immunology. 2021. 12. 712676
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Noriaki Miyanaga, Hideaki Takagi, Tomofumi Uto, Tomohiro Fukaya, Junta Nasu, Takehito Fukui, Yotaro Nishikawa, Tim Sparwasser, Narantsog Choijookhuu, Yoshitaka Hishikawa, et al. Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy. Communications biology. 2020. 3. 1. 742-742
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MISC (14)：
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深谷知宏, 宇都倫史, 三苫修也, 佐藤克明. 樹状細胞のはたらき5幼若期での抗生剤服用による消化管細菌叢異常に基づく経口免疫寛容の破綻における通常型樹状細胞の役割. Veterinary Immunology for Practitioners. 2024. 34. 15-21
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深谷知宏, 宇都倫史, 三苫修也, 佐藤克明. 樹状細胞のはたらき4経口免疫寛容の誘導における形質細胞様樹状細胞の役割. Veterinary Immunology for Practitioners. 2024. 33. 15-19
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深谷知宏, 宇都倫史, 三苫修也, 佐藤克明. 樹状細胞のはたらき3樹状細胞による制御性T細胞の制御. Veterinary Immunology for Practitioners. 2023. 32. 2-7
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宇都倫史, 深谷知宏, 三苫修也, 佐藤克明. 樹状細胞のはたらき2pDCsによる免疫応答制御. Veterinary Immunology for Practitioners. 2023. 31. 26-31
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宇都倫史, 深谷知宏, 三苫修也, 佐藤克明. 樹状細胞のはたらき1樹状細胞亜集団と免疫応答制御. Veterinary Immunology for Practitioners. 2023. 30. 32-38
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Books (2)：
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Current Topics in Microbiology and Immunology
Springer Publishing 2017
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Methods in Molecular Biology
Springer Publishing 2016
Lectures and oral presentations (46)：
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Crucial role of conventional dendritic cells in the generation of anti-tumor T-cell responses and immunogenic tumor microenvironment to suppress tumor development
(第52回日本免疫学会総会 2024)
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Clec4A4 serves as a negative immune checkpoint regulator expressed on conventional dendritic cells to impair antitumor immunity
(第52回日本免疫学会総会 2024)
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Gut dysbiosis abrogates the establishment of oral tolerance mediated through dysfunction of mucosal dendritic cells
(第52回日本免疫学会総会 2024)
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Selective cell stimulation with bovine interleukin-2 mutein and the distribution of bovine CD122 on the peripheral lymphocytes
(第52回日本免疫学会総会 2024)
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DCIR2 is an immune regulatory molecule expressed on conventional dendritic cells to suppress tumor immunity
(JSICR/MMCB 2023 Joint Symposium 2023)
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Professional career (1)：
Awards (1)：
- 2022/12 - 日本免疫学会 第51回日本免疫学会学術集会 ベストポスター賞 Gut dysbiosis abrogates the establishment of oral tolerance through the dysregulation of the crosstalk between CD103 + conventional dendritic cells and innate lymphoid cells in mesenteric lymph nodes
Association Membership(s) (1)：
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