2019 - 2022 Cooperative regulation of cytoskeleton and membrane dynamics by novel mechanism of dynamin
2019 - 2022 Elucidation of the function of novel actin-binding factors in neutrophil phagocytosis and extracellular trap formation
2018 - 2020 Genome-wide expression of P. falciparum membrane proteins
2017 - 2020 Analysis of membrane deforming proteins in Malaria parasite
2016 - 2019 Development of the anti-invasive drug for treatment of malignant glioma by drug-repositioning of anti-depressant.
2014 - 2017 Development of antimalarial drugs targeting the membrane trafficking
2014 - 2016 The role of endocytosis in oateoarhthritis
2011 - 2014 Multi-functionality of dynamin family and mechanism of integrated control
2011 - 2013 Development of antimalarial drug targeting plasmodium falciparum dynamin
2010 - 2012 Elucidation of Biological Adaptation and Remodeling Mechanisms to Mechanical Stress Based on the Development of Novel Micro-Electro-Mechanical Systems (MEMS) technology
2010 - 2012 The role of dynamin in actin dynamics: Development of anticancer drugs inhibiting dynamin function
2010 - 2012 The relationship between actin bundling by dynamin/cortactin complex and stretch-activated cation channel on actin cytoskeleton
2005 - 2007 Molecular mechanism of endocytosis that regulates membrane dynamics
2003 - 2007 エンドサイトーシスの分子機構:分子構造から細胞機能まで
2003 - 2005 Molecular mechanism of L-glutamate and GABA-mediated regulation of secretion of glucagon and insulin in islets of Langerhans
2003 - 2005 エンドサイト-シス小胞形成のリアルタイム観察
2002 - 2004 シナプスにおけるエンドサイトーシス機能タンパク-膜リン脂質相互作用の解析
2002 - 2004 A Study on Regulatory Mechanisms of Endocytosis
2002 - 2004 膵島におけるグルタミン酸によるインスリン分泌制御機構の解析
2001 - 2002 神経シナプスにおけるエンドサイトーシスの変化を指標とした神経変性疾患の解析
2001 - 2001 AMPA型グルタミン酸受容体のエンドサイトーシスの分子機構
2000 - 2001 A Study on Molecular Mechanisms of Endocytosis
Yamada, H, Osaka, H, Tatsumi, N, Araki, M, Abe, T, Kaihara, K, Takahashi, K, Takashima, E, Uchihashi, T, Naruse, K, et al. Direct Binding of Synaptopodin 2-Like Protein to Alpha-Actinin Contributes to Actin Bundle Formation in Cardiomyocytes. Cells. 2024. 13. 1373
Chia-Jung Chang, Zacharie Taoufiq, Hiroshi Yamada, Kohji Takei, Takami Tomiyama, Tomohiro Umeda, Tetsuya Hori, Tomoyuki Takahashi. The microtubule-dynamin binding inhibitor peptide PHDP5 rescues spatial learning and memory deficits in Alzheimer’s disease model mice. Brain Research. 2024. 148987-148987
Hiromichi Okuma, Yumiko Saijo-Hamano, Hiroshi Yamada, Aalaa Alrahman Sherif, Emi Hashizaki, Naoki Sakai, Takaaki Kato, Tsuyoshi Imasaki, Satoshi Kikkawa, Eriko Nitta, et al. Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I. Genes to Cells. 2023. 29. 1. 17-38
Haymar Win, Jianzhen Li, Tadashi Abe, Hiroshi Yamada, Takumi Higaki, Yasutomo Nasu, Masami Watanabe, Kohji Takei, Tetsuya Takeda. Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells. Journal of Cell Science. 2023. jcs.260827
Hiroshi Yamada, Tadashi Abe, Hikaru Nagaoka, Eizo Takashima, Ryo Nitta, Masahiro Yamamoto, Kohji Takei. Recruitment of Irgb6 to the membrane is a direct trigger for membrane deformation. Frontiers in Cellular and Infection Microbiology. 2022. 12. 992198-992198
