Mukai Takeo

Affiliation and department：

Research field (1)： Fetal medicine/Pediatrics

Research theme for competitive and other funds (10)：

2023 - 2026 Research and development of treatment for radiation-induced organ injuries using umbilical cord-derived mesenchymal stromal cells
2023 - 2025 臍帯由来細胞の神経保護効果におけるcell-to-cell contactの必要性の検討
2022 - 2025 A large prospective registry study to explore new indications for therapeutic hypothermia for neonatal encephalopathy
2021 - 2023 3D共培養における臍帯由来細胞の傷害ニューロン・ミクログリアへの遊走と被覆保護
2020 - 2022 Elucidation of mitochondrial regulation and actin dynamics of umbilical cord-derived mesenchymal cells on microglia

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Papers (45)：

Yoshihiko Shitara, Ryo Konno, Masahito Yoshihara, Kohei Kashima, Atsushi Ito, Takeo Mukai, Goh Kimoto, Satsuki Kakiuchi, Masaki Ishikawa, Tomo Kakihara, et al. Host-derived protein profiles of human neonatal meconium across gestational ages. Nature communications. 2024. 15. 1. 5543-5543
Takeo Mukai, Shota Kato, Hiroyuki Tanaka, Yukiko Kuroda, Hiroki Kitaoka, Atsushi Ito, Yoshihiko Shitara, Kohei Kashima, Hirokazu Takami, Naoto Takahashi, et al. A case of inherited glycosylphosphatidylinositol deficiency caused by PGAP3 variant with uniparental isodisomy on chromosome 17. Molecular genetics & genomic medicine. 2024. 12. 7. e2452
藤代準, 松田理奈, 一瀬諒紀, 高澤慎也, 吉田真理子, 大島拓也, 向井丈雄, 伊藤淳, 設楽佳彦, 鹿嶋晃平, et al. 先天性横隔膜ヘルニア術後の患側肺血管床の変化. 日本周産期・新生児医学会雑誌. 2024. 60. Suppl.1. P412-P412
Akiko Hori, Atsuko Takahashi, Yuta Miharu, Satoru Yamaguchi, Masatoshi Sugita, Takeo Mukai, Fumitaka Nagamura, Tokiko Nagamura-Inoue. Superior migration ability of umbilical cord-derived mesenchymal stromal cells (MSCs) toward activated lymphocytes in comparison with those of bone marrow and adipose-derived MSCs. Frontiers in cell and developmental biology. 2024. 12. 1329218-1329218
Yoshihiko Shitara, Etsushi Toyofuku, Hideki Doi, Takeo Mukai, Kohei Kashima, Satsuki Kakiuchi, Motohiro Kato, Naoto Takahashi. Congenital cytomegalovirus infection in a preterm infant with 22q11.2 deletion syndrome and immunological abnormalities. Nagoya journal of medical science. 2024. 86. 1. 149-154

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MISC (140)：

向井丈雄, 加登翔太, 田中裕之, 黒田友紀子, 大石紗也乃, 石原彩夏, 北岡寛己, 池山志豪, 衣斐恭介, 片山有里子, et al. PGAP3バリアントに17番染色体片親性イソダイソミーを伴った先天性GPI欠損症の1例. 日本小児科学会雑誌. 2024. 128. 2. 230-230
北岡寛己, 井上毅信, 黒田友紀子, 黒田友紀子, 伊藤淳, 白神一博, 衣斐恭介, 高見澤幸一, 廣畑晃司, 大島拓也, et al. A neonatal case of 8p partial trisomy with total anomalous pulmonary venous connection and feeding intolerance. 日本小児科学会雑誌. 2024. 128. 2
向井丈雄. 治療法の再整理とアップデートのために専門家による私の治療新生児遷延性肺高血圧症. 日本医事新報. 2024. 5204. 40-41
衣斐恭介, 北岡寛己, 片山有里子, 廣畑晃司, 大島拓也, 武藤浩司, 向井丈雄, 伊藤淳, 設樂佳彦, 井上毅信, et al. 先天性一過性高インスリン血症に新生児胆汁うっ滞を合併した早産児例. 日本新生児成育医学会雑誌. 2023. 35. 3. 560-560
内藤梨帆, 稲勝玲, 天願愛, 橘舞, 下屋聡平, 松原里奈, 瀬戸菜月, 荒川清美, 柘植美恵, 廣畑晃司, et al. How we prevent skin damage of extremely preterm infants?: Optimal incubator conditions and skin observation. 木村看護教育振興財団看護研究集録. 2023. 30. 16-27

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Books (4)：

Cerebral Palsy: Perspective, and Clinical Relation to Perinatal Complications/Events in Japan '22
2022 ISBN:9789811922169
脳性麻痺と周産期合併症/イベントとの関連 : 最新の知見
メジカルビュー社 2021 ISBN:9784758321303
Cell Therapy for Perinatal Brain Injury(Chapter 6)
Springer International 2018
2015 CoSTRに基づいた新生児低体温療法実践マニュアル
東京医学社 2016

Lectures and oral presentations (30)：

早産児と先天性心疾患児の臍帯プロテオーム解析
(第60回日本周産期・新生児医学会学術集会 2024)
PGAP3バリアントに17番染色体片親性イソダイソミーを伴った先天性GPI欠損症の1例
(第127回日本小児科学会学術集会 2024)
New developments in mesenchymal stem cell therapy for pediatric nervous system diseases
(2024)
Current status of elucidating the mechanism of action of mesenchymal stem cell and hematopoietic stem cell transplantation treatments
(2024)
A case of uniparental isodisomy of chromosome 17 with Blake's pouch cyst
(2023)

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Education (2)：

2014 - 2018 The University of Tokyo Graduate School of Medicine
2001 - 2007 Kyoto University Medical faculty

Professional career (1)：

PhD (Medical Science)

Work history (9)：

2020/04 - 現在 The University of Tokyo Hospital Department of Pediatrics Assistant Professor
2020/04 - 現在 Institute of Medical Science, the University of Tokyo Umbilical cord blood & cord bank part-time teacher
2020/01 - 2020/03 Institute of Medical Science, the University of Tokyo Department of Cell processing and Transfusion post doc
2019/04 - 2019/12 Karolinska Institute Department of Women’s and Children’s Health Postdoc
2018/05 - 2019/03 Karolinska Institute Department of Women’s and Children’s Health Research Fellowship of Japan Society for the Promotion of Science (JSPS)

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Awards (5)：

2024 - 森永奉仕会研究奨励金特別賞太田敬三記念賞
2018 - The Japanese Society for Regenerative Medicine Research Encouragement Prize
2017 - The 8th Asian Cellular Therapy Organization Best Poster Award
2017 - The 17th Bio-UT, The University of Tokyo Excellent Poster Award
2016 - The 3rd Seminar of Graduate School of Medicine, The University of Tokyo Excellent Poster Award

Association Membership(s) (4)：

JAPAN PEDIATRIC SOCIETY , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , JAPAN SOCIETY FOR NEONATAL HEALTH AND DEVELOPMENT , JAPAN SOCIETY OF PERINATAL AND NEONATAL MEDICINE

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