Rchr
J-GLOBAL ID：201801006124959116
Update date: Nov. 12, 2024
Shimizu Masahiro
シミズ マサヒロ | Shimizu Masahiro
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Molecular biology
Research theme for competitive and other funds (3)：
- 2019 - 2021 炎症性ケモカインIL-8依存的に制御される癌幹細胞の同定と制御機構の解析
- 2017 - 2020 Generation and maintenance mechanism of cancer stem cells in tumor microenvironment, involved in lung cancer development and reocurrence.
- がん幹細胞の発生・機能維持機構の解析
Papers (6)：
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Masahiro Shimizu, Hiroshi Shibuya. WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway. Scientific reports. 2022. 12. 1. 15858-15858
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Masahiro Shimizu, Hiroshi Shibuya, Nobuyuki Tanaka. Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells. Scientific reports. 2022. 12. 1. 2910-2910
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Sato Atsushi, Shimizu Masahiro, Goto Toshiyasu, Masuno Hiroyuki, Kagechika Hiroyuki, Tanaka Nobuyuki, Shibuya Hiroshi. WNK regulates Wnt signalling and beta-Catenin levels by interfering with the interaction between beta-Catenin and GID. COMMUNICATIONS BIOLOGY. 2020. 3. 1
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Masahiro Shimizu, Nobuyuki Tanaka. IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells. Oncogene. 2019. 38. 9. 1520-1533
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Masahiro Shimizu, Toshiyasu Goto, Atsushi Sato, Hiroshi Shibuya. WNK4 is an essential effector of anterior formation in FGF signaling. Genes to cells : devoted to molecular & cellular mechanisms. 2013. 18. 6. 442-9
ｍore...
Lectures and oral presentations (3)：
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Mechanism of IL-8 dependent regulation of cancer stem cells
(The 43rd Annual Meeting of the Molecular Biology Society of Japan 2020)
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癌細胞の不均一性がもたらすIL-8依 存的な癌幹細胞の制御機構の解析
(第88 回 日本医科大学医学会総会 2020)
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ケモカインIL-8による糖代謝の制御機構とがん幹細胞への影響
(生命科学系学会合同年次大会 2017)
Work history (2)：
- 2019/09/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Life Science and Technology Life Science and Technology Molecular Cell Biology Assistant Professor
- 2019/09/01 - 現在 Tokyo Medical and Dental University Medical Research Institute Advanced Molecular Medicine Molecular Cell Biology Assistant Professor
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