Research field (5)：
Cell biology
, Gastroenterology
, Molecular biology
, Nutrition and health science
, Hygiene and public health (laboratory)
Research theme for competitive and other funds (15)：
2024 - 2027 Elucidation of the pathophysiological condition and inter-organ network in childhood obesity through single particle analysis of extracellular vesicles
2022 - 2025 胆汁酸を起点とした肝筋連関の解明と肝性サルコペニアの診断・治療
2022 - 2025 膵癌進展の病態伝播を担う細胞外小胞の機能解明~臨床応用を目指して~
2021 - 2024 小児肥満における細胞外小胞を介した代謝調節ネットワークの解明
2021 - 2024 Evaluation of roles of ubiquitin-specific proteases in NAFLD/NASH pathogenesis using cell-specific gene-engineered mouse models
2020 - 2023 疲労関連タンパク質を用いた任意型健康診断集団における疾病予測研究
2018 - 2021 Treatment of sepsis with exosomal thrombomodulin
2017 - 2021 Survey and Intervention Research on Prevention of Both Mental and Physical Diseases Using Fatigue and Extracellular Vesicle Markers
2017 - 2020 Investigation of arteriosclerosis associating with liver derived extracellular vesicles in alcohlic liver disease
2017 - 2020 Elucidation of new metabolism promotion mechanism through extracellular vesicles derived from skeletal muscle
2016 - 2020 The role of low entropy extracellular vesicles derived from steatotic liver cells on the generation of atherosclerosis
2016 - 2019 The peritoneum omentum exosomes in the septic immune paralysis
2016 - 2018 The hepatosomes released from damaged hepatocytes will contribute the progression of ALD
2016 - 2018 The ability of human extracellular vesicles to augment inflammatory host response in septic shock
2015 - 2017 Developmen of the novel diagnostic marker for chornic fatigue tarageting circulating particles
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Papers (120)：
Motoh Iwasa, Ryosuke Sugimoto, Akiko Eguchi, Yasuyuki Tamai, Ryuta Shigefuku, Naoto Fujiwara, Hideaki Tanaka, Yoshinao Kobayashi, Jiro Ikoma, Masahiko Kaito, et al. Effectiveness of 1-year pemafibrate treatment on steatotic liver disease: the influence of alcohol consumption. European journal of gastroenterology & hepatology. 2024. 36. 6. 793-801
