Deguchi Takao

デグチタカオ | Deguchi Takao

Affiliation and department：
Job title：診療部長

Research field (1)： Fetal medicine/Pediatrics

Research keywords (2)： Pediatric hematology-oncology , Pediatrics

Research theme for competitive and other funds (5)：

2023 - 2026 小児から若年成人における進行期骨髄異形成症候群の多元的病態解析と予後因子の解明
2021 - 2023 Establishment of AI diagnostic technology for hematologic malignancy
2011 - 2013 Characteristics of leukemic stem cell activity in minimal residual disease of pediatric acute lymphoblastic leukemia
2004 - 2005 Regenerative therapy against pulmonary hypertension by using bone marrow-derived stem cells
2003 - 2004 造血幹細胞の未分化性維持と分化におけるインターロイキン3レセプター発現の意義

Papers (105)：

Motohiro Kato, Yasuhiro Okamoto, Toshihiko Imamura, Akiko Kada, Akiko M. Saito, Yuka Iijima-Yamashita, Takao Deguchi, Kentaro Ohki, Takashi Fukushima, Kenichi Anami, et al. JCCG ALL-B12: Evaluation of Intensified Therapies With Vincristine/Dexamethasone Pulses and Asparaginase and Augmented High-Dose Methotrexate for Pediatric B-ALL. Journal of Clinical Oncology. 2024
Junko Yamanaka, Chitose Ogawa, Ayumu Arakawa, Takao Deguchi, Toshinori Hori, Nobutaka Kiyokawa, Hideaki Ueki, Masanori Nishi, Shinji Mochizuki, Takuro Nishikawa, et al. Outcomes in children with first-relapsed acute lymphoblastic leukemia in Japan: Results from JCCG Study JPLSG-ALL-R08. Pediatric blood & cancer. 2024. e31319
Shota Kato, Shin-Ichi Tsujimoto, Jun Matsubayashi, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, et al. Adverse prognostic impact of <i>KIT</i> exon 17 mutations despite negative flow cytometric measurable residual disease in pediatric acute myeloid leukemia with <i>RUNX1::RUNX1T1</i>. Haematologica. 2024
Norihito Ikenobe, Kentaro Fujimori, Yoshihiro Gocho, Shota Myojin, Masaki Yamada, Kenichi Imadome, Mikiko Miyasaka, Osamu Miyazaki, Akihiro Yoneda, Shotaro Matsumoto, et al. Successful management with urgent haploidentical-peripheral blood stem cell transplantation for a patient with severe aplastic anaemia who developed disseminated fungal infection following immunosuppressive therapy. eJHaem. 2024
Shunsuke Kimura, Chun Shik Park, Lindsey E Montefiori, Ilaria Iacobucci, Petri Polonen, Qingsong Gao, Elizabeth D Arnold, Andishe Attarbaschi, Anthony Brown, Barbara Buldini, et al. Biologic and clinical analysis of childhood gamma delta T-ALL identifies LMO2/STAG2 rearrangements as extremely high-risk. Cancer discovery. 2024

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MISC (345)：

安江志保, 坂口大俊, 藤森健太郎, 内山徹, 八角高裕, 大野沙耶香, 金裕花, 樋口徹, 牛腸義宏, 井口晶裕, et al. A case of an infant with familial hemophagocytic lymphohistiocytosis type 2 treated with cord blood transplantation. 日本小児科学会雑誌. 2024. 128. 2. 238-238
坂口大俊, 蘇哲民, 小須賀基通, 牛腸義宏, 出口隆生, 井口晶裕, 富澤大輔, 松本公一. Hematopoietic Cell Transplantation and Intracerebroventricular Enzyme Replacement for Mucopolysaccharidosis type II. 日本小児科学会雑誌. 2024. 128. 2. 283-283
辻本信一, 加登翔太, 岩本彰太郎, 平松英文, 奥野友介, 神鳥達哉, 大木健太郎, 出口隆生, 清河信敬, 加藤元博, et al. KIT変異・FCM-MRDはRUNX1::RUNX1T1RUNX1陽性小児AMLにおける予後予測因子である. 日本血液学会学術集会. 2023. 85回. 142-142
横道萌, 清水大輔, 内村真介, 牧野理沙, 比良洸太, 出口隆生, 坂口公祥. 骨壊死合併再発ALLに対するステロイドを使用しない化学療法とCAR-T療法. 日本血液学会学術集会. 2023. 85回. 1267-1267
藤森健太郎, 坂口広俊, 牛腸義宏, 歌野智之, 山田悠司, 内山徹, 塩田曜子, 清谷知賀子, 寺島慶太, 井口晶裕, et al. 小児B細胞性急性リンパ性白血病に対するブリナツモマブの後方視的検討. 日本血液学会学術集会. 2023. 85回. 1363-1363

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Education (2)：

1992 - 1998 Mie University Graduate School of Medicine
1984 - 1990 Mie University Faculty of Medicine School of Medecine

Professional career (1)：

医学博士 (三重大学)

Work history (6)：

2018/04 - 現在 National Center for Child Health and Development Division of Immunodiagnostics, Children's Cancer Center Head of division
2010/04 - 2018/03 Mie University Hospital
2002/07 - 2010/03 Mie University Hospital
2000/02 - 2002/06 サウスカロライナ医科大学小児血液腫瘍学/実験血液学博士研究員
1999/01 - 2000/01 国立三重中央病院小児科・臨床研究部医長

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Association Membership(s) (8)：

日本小児リウマチ学会 , 日本免疫不全・自己炎症学会 , 日本造血・免疫細胞療法学会 , 国際小児がん学会 , 米国血液学会 , THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY , THE JAPANESE SOCIETY OF HEMATOLOGY , JAPAN PEDIATRIC SOCIETY

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