Rchr
J-GLOBAL ID:201801006560051529   Update date: Sep. 08, 2024

Shinohara Mitsuru

Shinohara Mitsuru
Affiliation and department:
Research keywords  (3): 危険因子 ,  認知症 ,  アルツハイマー病
Research theme for competitive and other funds  (4):
  • 2021 - 2025 アルツハイマー病保護因子APOE2多型の作用機序の解明と治療薬開発への応用
  • 2021 - 2025 アルツハイマー病保護因子APOE2多型の作用機序の解明と治療薬開発への応用
  • 2018 - 2021 Study of two-step amyloid-beta accumulation in human brains
  • 2017 - 2019 アミロイドβの蓄積をもたらすシナプスの分子的実態の解明
Papers (52):
  • Mitsuru Shinohara, Ghupurjan Gheni, Junichi Hitomi, Guojun Bu, Naoyuki Sato. APOE genotypes modify the obesity paradox in dementia. Journal of Neurology, Neurosurgery and Psychiatry. 2023. 94. 9. 670-680
  • Yukiko Nishita, Giovanni Sala, Mitsuru Shinohara, Chikako Tange, Fujiko Ando, Hiroshi Shimokata, Naoyuki Sato, Rei Otsuka. Effects of APOEɛ4 genotype on age-associated change in cognitive functions among Japanese middle-aged and older adults: A 20-year follow-up study. Experimental Gerontology. 2023. 171. 112036-112036
  • Naoki Saji, Kenta Murotani, Naoyuki Sato, Tsuyoshi Tsuduki, Takayoshi Hisada, Mitsuru Shinohara, Taiki Sugimoto, Shumpei Niida, Kenji Toba, Takashi Sakurai. Relationship Between Plasma Neurofilament Light Chain, Gut Microbiota, and Dementia: A Cross-Sectional Study. Journal of Alzheimer's Disease. 2022. 86. 3. 1323-1335
  • Mitsuru Shinohara, Junko Hirokawa, Akemi Shimodaira, Yoshitaka Tashiro, Kaoru Suzuki, Ghupurjan Gheni, Akio Fukumori, Tomoyasu Matsubara, Maho Morishima, Yuko Saito, et al. ELISA Evaluation of Tau Accumulation in the Brains of Patients with Alzheimer Disease. Journal of neuropathology and experimental neurology. 2021. 80. 7. 652-662
  • Mitsuru Shinohara, Masataka Kikuchi, Miyuki Onishi-Takeya, Yoshitaka Tashiro, Kaoru Suzuki, Yasuhiro Noda, Shuko Takeda, Masahiro Mukouzono, Seiichi Nagano, Akio Fukumori, et al. Upregulated expression of a subset of genes in APP;ob/ob mice: Evidence of an interaction between diabetes-linked obesity and Alzheimer's disease. FASEB bioAdvances. 2021. 3. 5. 323-333
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MISC (48):
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Professional career (1):
  • Intermanl Medicine (Osaka University)
Work history (4):
  • 2021/04 - 現在 National Center for Geriatrics and Gerontrogy
  • 2017/02 - 2021/03 国立長寿医療研究センター 分子基盤研究部 室長
  • 2010/11 - 2017/01 Mayo Clinic
  • 2010/08 - 2010/08 Washington University School of Medicine 研究員
Awards (25):
  • 2021 - 武田科学振興財団 2021年度医学系研究助成(精神・神経・脳領域)
  • 2020 - 中京長寿医療研究推進財団 第9回医学研究助成金
  • 2020 - 小野医学研究財団 第29回研究奨励助成金
  • 2020 - 金原一郎記念医学医療振興財団 第35回基礎医学医療研究助成金
  • 2020 - 日本老年医学会 第2回日本老年医学会YIA
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